Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Carl O Olson"'
Autor:
Carl O. Olson, Shervin Pejhan, Daniel Kroft, Kimia Sheikholeslami, David Fuss, Marjorie Buist, Annan Ali Sher, Marc R. Del Bigio, Yehezkel Sztainberg, Victoria Mok Siu, Lee Cyn Ang, Marianne Sabourin-Felix, Tom Moss, Mojgan Rastegar
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Rett syndrome (RTT) is a severe and rare neurological disorder that is caused by mutations in the X-linked MECP2 (methyl CpG-binding protein 2) gene. MeCP2 protein is an important epigenetic factor in the brain and in neurons. In Mecp2-deficient neur
Externí odkaz:
https://doaj.org/article/d5ec5417e1f1402e90cc3f8fa5bb1e26
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 8, p 1845 (2019)
Methyl CpG binding protein-2 (MeCP2) isoforms (E1 and E2) are important epigenetic regulators in brain cells. Accordingly, MeCP2 loss- or gain-of-function mutation causes neurodevelopmental disorders, including Rett syndrome (RTT), MECP2 duplication
Externí odkaz:
https://doaj.org/article/d7f136ad28c64ac9b4d1fd967bf2d291
Autor:
Carl O. Olson, Robby M. Zachariah, Geoffrey G. Hicks, Wayne Xu, Romina D. Levy, Aaron MacAulay, James R. Davie, Kyle Curtis, Marjorie Buist, Shayan Amiri, Mojgan Rastegar, Vichithra R. B. Liyanage
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
We have previously reported the deregulatory impact of ethanol on global DNA methylation of brain-derived neural stem cells (NSC). Here, we conducted a genome-wide RNA-seq analysis in differentiating NSC exposed to different modes of ethanol exposure
Autor:
Carl O Olson, Robby M Zachariah, Chinelo D Ezeonwuka, Vichithra R B Liyanage, Mojgan Rastegar
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90645 (2014)
MeCP2 is a critical epigenetic regulator in brain and its abnormal expression or compromised function leads to a spectrum of neurological disorders including Rett Syndrome and autism. Altered expression of the two MeCP2 isoforms, MeCP2E1 and MeCP2E2
Externí odkaz:
https://doaj.org/article/047f4ba6b42345e188dbaa95e4f78880
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49763 (2012)
Rett Syndrome (RTT) is a severe neurological disorder in young females, and is caused by mutations in the X-linked MECP2 gene. MECP2/Mecp2 gene encodes for two protein isoforms; MeCP2E1 and MeCP2E2 that are identical except for the N-terminus region
Externí odkaz:
https://doaj.org/article/80e9475b280a4978b3e7791de294ed18
Autor:
Annan Ali Sher, Marjorie Buist, Marc R. Del Bigio, Victoria Mok Siu, Shervin Pejhan, Marianne Sabourin-Felix, Mojgan Rastegar, Tom Moss, Carl O. Olson, David Fuss, Lee Cyn Ang, Daniel Kroft, Kimia Sheikholeslami, Yehezkel Sztainberg
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics
Frontiers in Genetics
Rett syndrome (RTT) is a severe and rare neurological disorder that is caused by mutations in the X-linked MECP2 (methyl CpG-binding protein 2) gene. MeCP2 protein is an important epigenetic factor in the brain and in neurons. In Mecp2-deficient neur
Autor:
Carl O. Olson, Hossein Amini-Khoei, Shayan Amiri, Sakineh Alijanpour, Ali Razmi, Ali Mohammadi-Asl, Mehdi Mehdizadeh, Mojgan Rastegar, Maryam Rahimi-Balaei, Arya Haj-Mirzaian, Mohammad-Reza Zarrindast
Publikováno v:
Physiology & Behavior. 163:107-114
Mother-infant interactions are known to be associated with the psychological well-being of an individual in adulthood. It is well accepted that emotional stress in early life, such as maternal separation (MS), leads to alterations in the neurotransmi
Autor:
Arya Haj-Mirzaian, Armin Shirzadian, Mohammad-Reza Zarrindast, Maryam Rahimi-Balaei, Shayan Amiri, Arman Mohsenzadeh, Carl O. Olson, Ali Razmi, Hossein Amini-Khoei, Mojgan Rastegar, Mahmoud Ghazi-Khansari
Publikováno v:
European journal of pharmacology. 797
Adolescence is a pivotal period of brain development during lifespan, which is sensitive to stress exposure. Early social isolation stress (SIS) is known to provoke a variety of psychiatric comorbidities as well as seizure risk. Psychiatric comorbidi
Autor:
N. Kamasawa, James I. Nagy, Carl O. Olson, John E. Rash, Thomas Yasumura, Kimberly G. V. Davidson
Publikováno v:
Neuroscience. 147:938-956
Locus coeruleus neurons are strongly coupled during early postnatal development, and it has been proposed that these neurons are linked by extraordinarily abundant gap junctions consisting of connexin32 and connexin26, and that those same connexins a
Autor:
John E. Rash, F.E. Dudek, Carl O. Olson, Alberto E. Pereda, Kimberly G. V. Davidson, James I. Nagy, N. Kamasawa, Xinbo Li, C. S. Furman, Thomas Yasumura
Publikováno v:
Journal of Neurocytology. 33:131-151
Combined confocal microscopy and freeze-fracture replica immunogold labeling (FRIL) were used to examine the connexin identity at electrical synapses in goldfish brain and rat retina, and to test for "co-localization" vs. "close proximity" of connexi