Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Carl N. Martin"'
Autor:
Gregor Liegl, Felix H. Fischer, Carl N. Martin, Maria Rönnefarth, Annelie Blumrich, Michael Ahmadi, Leif-Hendrik Boldt, Kai-Uwe Eckardt, Matthias Endres, Frank Edelmann, Holger Gerhardt, Ulrike Grittner, Arash Haghikia, Norbert Hübner, Ulf Landmesser, David Leistner, Knut Mai, Jil Kollmus-Heege, Dominik N. Müller, Christian H. Nolte, Sophie K. Piper, Kai M. Schmidt-Ott, Tobias Pischon, Simrit Rattan, Ira Rohrpasser-Napierkowski, Katharina Schönrath, Jeanette Schulz-Menger, Oliver Schweizerhof, Joachim Spranger, Joachim E. Weber, Martin Witzenrath, Sein Schmidt, Matthias Rose
Publikováno v:
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Health-related quality of life (HRQL) has become an important outcome parameter in cardiology. The MOS 36-ltem Short-Form Health Survey (SF-36) and the PROMIS-29 are two widely used generic measures providing composite HRQL scores
Externí odkaz:
https://doaj.org/article/e16e431aec684125985e3087cdefce6b
Autor:
Carl N. Martin, Susan F. Ekers
Publikováno v:
Carcinogenesis. 1(1)
3H Benzidine, injected i.p. into male Wistar rats, was shown to bind to liver macromolecules including DNA. Binding to DNA was persistent, significant amounts of radioactivity being detected four weeks after injection. Enzymic digestion of the DNA re
Autor:
Carl N. Martin, David W. Birch
Publikováno v:
Animal Cell Culture Techniques ISBN: 9783540630081
In 1973, genetic engineering was born following the pioneering work of Cohen and co-workers in California, who cloned a synthetic DNA molecule into a bacterium such that the constructed molecule was passed to daughter cells. Following these initial e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e8e09737833b4a0d947a6b5dadadcd
https://doi.org/10.1007/978-3-642-80412-0_27
https://doi.org/10.1007/978-3-642-80412-0_27
Autor:
Gary S. Jennings, Carl N. Martin
Publikováno v:
Nitroarenes ISBN: 9781461366942
1-Nitropyrene is an ubiquitous environmental pollutant which has been detected in the urban atmosphere in many areas of the world (1). It is generated primarily by incomplete combustion of fossil fuels and thus is present in relatively high concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5320d0db67878c6a6cae6fefa16f2cfe
https://doi.org/10.1007/978-1-4615-3800-4_14
https://doi.org/10.1007/978-1-4615-3800-4_14
Publikováno v:
Mutation Research/Genetic Toxicology. 137:39-45
The conventional Ames assay metabolising system was confirmed to be deficient in its ability to N -acetylate. This may render the test less sensitive to compounds which normally have an acetylation step during their in vivo activation to carcinogens.
Publikováno v:
Carcinogenesis. 3:1423-1427
Generally labelled [3H]6-nitrobenzo[a]pyrene (6NBP) when administered to male rats by i.p. injection was widely distributed throughout the body. After a single injection of 4.2 mg/kg the highest concentration was found in the liver (5% at 2 h) follow
Publikováno v:
Carcinogenesis. 8:1189-1192
The administration of [3H]BPDE-DNA, whether by i.p. or i.v. injection, to male Wistar rats resulted in the majority of the radioactivity being recovered in the faeces. Excretion was rapid: within 24 h post-injection, 45% of the applied dose was recov
Autor:
F. L. Chow, David H. Phillips, P.L. Grover, Carl N. Martin, Caroline A. Stanton, R. C. Garner
Publikováno v:
Carcinogenesis. 6:535-538
[3H]1-Nitropyrene was administered at a dose of 25 mg/kg by i.p. injection to female Wistar rats. Animals were killed 24 h later and DNA was isolated from kidney, liver and mammary gland, enzymically hydrolysed and analysed by reverse-phase h.p.l.c.
Autor:
Carl N. Martin
Publikováno v:
Toxicology. 18:233-237
Isolated rat hepatocytes are being used in a variety of ways to answer fundamental questions concerning the metabolism of chemical compounds. These cells retain a high capacity to metabolise xenobiotics when treated shortly after isolation, as either
Publikováno v:
Biochemical Pharmacology. 38:279-287
The binding of [ring-3H]4,4'-methylenebis(2-chloroaniline) (MOCA) to rat liver DNA following i.p. injection is demonstrated. Three discrete adducts were eluted on HPLC following enzymic hydrolysis to the nucleoside level. Three adducts, with the same