Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Carl Murie"'
Autor:
Julian Rothen, Carl Murie, Jason Carnes, Atashi Anupama, Salim Abdulla, Mwajuma Chemba, Maxmillian Mpina, Marcel Tanner, B Kim Lee Sim, Stephen L Hoffman, Raphael Gottardo, Claudia Daubenberger, Ken Stuart
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199392 (2018)
Malaria continues to be one of mankind's most devastating diseases despite the many and varied efforts to combat it. Indispensable for malaria elimination and eventual eradication is the development of effective vaccines. Controlled human malaria inf
Externí odkaz:
https://doaj.org/article/8e8d2c41a2a54c209bbc05676e6efe80
Autor:
Raphael Gottardo, Jason Carnes, John J. Aponte, Chenjerai Jairoce, Lindsay N. Carpp, Hector Sanz, Joseph J. Campo, Maximillian Mpina, M. Juliana McElrath, Daniel E. Neafsey, Clarissa Valim, Selidji T Agnandji, William Chad Young, Carlota Dobaño, Phu T. Van, Paige Haas, Carl Murie, Sheetij Dutta, Stephen C. De Rosa, Nana Aba Williams, Claudia Daubenberger, Gemma Moncunill, Augusto Nhabomba, Núria Díez-Padrisa, Kenneth Stuart, Greg Finak, Benjamin Mordmüller
In a phase 3 trial in African infants/children, the RTS,S/AS01 (GSK) vaccine showed moderate efficacy against clinical malaria. We aimed to identify RTS,S/AS01-induced signatures associated with clinical malaria by analyzing antigen-stimulated periph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff8c9387749a4811a9213a6a0b178706
https://doi.org/10.1101/2021.05.19.21257227
https://doi.org/10.1101/2021.05.19.21257227
Autor:
Carl Murie, Christine H. Wendt, Ann Sofi Sandberg, Brian J Sandri, Timothy J. Griffin, Ola Larsson, Janne Lehtiö
Publikováno v:
Advances in Biological Regulation. 67:128-133
iTRAQ and TMT reagent-based mass spectrometry (MS) are commonly used technologies for quantitative proteomics in biological samples. Such studies are often performed over multiple MS runs, potentially resulting in introduction of MS run bias that cou
Autor:
Ping Yang, Ola Larsson, Charlotte Rolny, Carl Murie, Brian J Sandri, Margarita Bartish, Jonas Bergh, Timothy J. Griffin, Svetlana Avdulov, Todd W. Markowski, Mark Peterson, Chris H. Wendt, Laia Masvidal, Andrew H. Limper, Peter B. Bitterman, LeeAnn Higgins
Publikováno v:
Am J Respir Crit Care Med
Rationale: Chronic obstructive pulmonary disease is an independent risk factor for lung cancer, but the underlying molecular mechanisms are unknown. We hypothesized that lung stromal cells activate pathological gene expression programs that support o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1594537c99cdd8adcba466bccda5b6d7
https://europepmc.org/articles/PMC6680296/
https://europepmc.org/articles/PMC6680296/
Publikováno v:
Nucleic Acids Research
mRNA translation plays an evolutionarily conserved role in homeostasis and when dysregulated contributes to various disorders including metabolic and neurological diseases and cancer. Notwithstanding that optimal and universally applicable methods ar
Autor:
Carl Murie, Ivan Topisirovic, Luc Furic, Valentina Gandin, Laia Masvidal, Marie Cargnello, Ola Larsson, Julie Lorent, Christian Oertlin
mRNA translation plays an evolutionarily conserved role in homeostasis and when dysregulated results in various disorders. Optimal and universally applicable analytical methods to study transcriptome-wide changes in translational efficiency are there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c79e478ab786ada4c59b8517ab7314
https://doi.org/10.1101/106922
https://doi.org/10.1101/106922
Publikováno v:
Bioinformatics
Bioinformatics, 2013, 29 (23), pp.3067-3072. ⟨10.1093/bioinformatics/btt538⟩
Bioinformatics, Oxford University Press (OUP), 2013, 29 (23), pp.3067-3072. ⟨10.1093/bioinformatics/btt538⟩
Bioinformatics, 2013, 29 (23), pp.3067-3072. ⟨10.1093/bioinformatics/btt538⟩
Bioinformatics, Oxford University Press (OUP), 2013, 29 (23), pp.3067-3072. ⟨10.1093/bioinformatics/btt538⟩
Motivation: Advantages of statistical testing of high-throughput screens include P-values, which provide objective benchmarks of compound activity, and false discovery rate estimation. The cost of replication required for statistical testing, however
Autor:
Sanjana, Sood, Krzysztof J, Szkop, Asif, Nakhuda, Iain J, Gallagher, Carl, Murie, Robert J, Brogan, Jaakko, Kaprio, Heikki, Kainulainen, Philip J, Atherton, Urho M, Kujala, Thomas, Gustafsson, Ola, Larsson, James A, Timmons
Publikováno v:
Nucleic Acids Research
DNA microarrays and RNAseq are complementary methods for studying RNA molecules. Current computational methods to determine alternative exon usage (AEU) using such data require impractical visual inspection and still yield high false-positive rates.
Autor:
Salim Abdulla, Marcel Tanner, Julian Rothen, Kenneth Stuart, Raphael Gottardo, Atashi Anupama, B. Kim Lee Sim, Carl Murie, Stephen L. Hoffman, Claudia Daubenberger, Maxmillian Mpina, Mwajuma Chemba, Jason Carnes
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199392 (2018)
Malaria continues to be one of mankind's most devastating diseases despite the many and varied efforts to combat it. Indispensable for malaria elimination and eventual eradication is the development of effective vaccines. Controlled human malaria inf
Autor:
Carl Murie, Ping Yang, Ola Larsson, Chris H. Wendt, Timothy J. Griffin, LeeAnn Higgins, Peter B. Bitterman, Todd W. Markowski, Pratik D. Jagtap, Brian J Sandri, Svetlana Avdulov, Andrew H. Limper, Mark Peterson
Publikováno v:
11.1 Lung Cancer.
Introduction: Chronic Obstructive Pulmonary Disease (COPD), independent of smoking, is a risk factor for lung cancer. To pursue this link we use iTRAQ labeling with MS/MS to identify putative molecular pathways in the etiology of lung cancer associat