Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Carl Monder"'
Publikováno v:
Steroids. 62:403-408
16-Methylene-17 alpha-hydroxy-19-norpregn-4-ene-3,20-dione 1 and its 17 alpha-acylated derivatives were synthesized. The length of the 17 alpha-side-chain ranges from C2-C6. As anticipated, compound 1 did not show any progestational activity or recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601ba7df84e25984f4062b1978700806
https://doi.org/10.1016/s0039-128x(97)00005-6
https://doi.org/10.1016/s0039-128x(97)00005-6
Publikováno v:
Endocrinology. 137:1714-1718
In vitro studies have shown that corticosterone (B) directly inhibits testosterone (T) production by purified Leydig cells but does so only at high concentrations. 11 beta-Hydroxysteroid dehydrogenase (11 beta-HSD) in Leydig cells oxidatively inactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62ca2e2f40e24a1d1f53d3b8c55e0b1
https://doi.org/10.1210/endo.137.5.8612506
https://doi.org/10.1210/endo.137.5.8612506
Autor:
F. Arcuri, Stefania Battistini, Carl Monder, Frederick Schatz, V. Hausknecht, Charles J. Lockwood
Publikováno v:
Annals of the New York Academy of Sciences. 784:433-438
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76ad1bcd9eee157863ea379556df039
https://doi.org/10.1111/j.1749-6632.1996.tb16258.x
https://doi.org/10.1111/j.1749-6632.1996.tb16258.x
Publikováno v:
Endocrinology. 137:595-600
This study evaluated the expression of the corticosteroid-metabolizing enzyme 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) during in vitro decidualization of human endometrial stromal cells. The cultured stromal cells displayed both NADP(+)-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7fb3fdcb4a119a7b697c1fc1c428d7
https://doi.org/10.1210/endo.137.2.8593807
https://doi.org/10.1210/endo.137.2.8593807
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1248:70-74
11 β-hydroxysteroid dehydrogenase (11-HSD) catalyzes the interconversion of corticosterone and 11-dehydrocorticosterone in rats, or cortisol and cortisone in humans. The ‘liver’ or ‘Type I’ isozyme is a widely distributed glycoprotein that u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e924c5d6c25beeafe2e76f1933d57ea
https://doi.org/10.1016/0167-4838(95)00005-f
https://doi.org/10.1016/0167-4838(95)00005-f
Publikováno v:
Journal of Biological Chemistry. 269:25959-25962
11 beta-Hydroxysteroid dehydrogenase (11-HSD) catalyzes the conversion of cortisol to cortisone and corticosterone to 11-dehydrocorticosterone. This activity may be required to confer normal ligand specificity upon the mineralocorticoid receptor. Alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993ad1fd39f27c1209d37e4a3d597f95
https://doi.org/10.1016/s0021-9258(18)47142-6
https://doi.org/10.1016/s0021-9258(18)47142-6
Publikováno v:
Journal of neuroendocrinology. 4(1)
The dehydrogenase form of 11 β-hydroxysteroid dehydrogenase (11-DH) which catalyzes the oxidation of the biologically active steroid, corticosterone, to its inactive metabolite, 11-dehydrocorticosterone, is found in rat brain. The distribution and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa573956494dc01f9bde7258d5693f0
https://pubmed.ncbi.nlm.nih.gov/21554583
https://pubmed.ncbi.nlm.nih.gov/21554583
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 46:209-213
Carbenoxolone (CX), the succinyl ester of glycyrrhetinic acid, causes hypokalemia and hypernatremia. Its pharmacological effects are believed to be due to its inhibition of 11 beta-hydroxysteroid dehydrogenase (11-HSD). There was a marked inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6a562e7cbce700fe5f0cfc160095fa
https://doi.org/10.1016/0960-0760(93)90296-9
https://doi.org/10.1016/0960-0760(93)90296-9
Autor:
Iren Vincze, Carl Monder
Publikováno v:
Contraception. 47:507-514
We describe the chemical synthesis of the 2 beta-propionate-17 beta- hemisuccinate and 2 beta-hemisuccinate-17 beta-propionate diesters of anordiol (2 alpha,17 alpha-diethynyl-A-nor-5 alpha-androstane-2 beta,17 beta-diol) and the method for coupling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d2b77a8cfb32e53cde655dd6115dbd
https://doi.org/10.1016/0010-7824(93)90103-e
https://doi.org/10.1016/0010-7824(93)90103-e
Autor:
Carl Monder
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 45:161-165
In this review, we consider the relationship between the structure and function of 11β-hydroxysteroid dehydrogenase (11-HSD) purified from rat liver. The rat liver enzyme is a single domain glycoprotein with a unique active site and belongs to the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa6b44f3395cd842906e032afec6eea
https://doi.org/10.1016/0960-0760(93)90136-k
https://doi.org/10.1016/0960-0760(93)90136-k