Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Carl M. Blumenfeld"'
Autor:
Carl M. Blumenfeld, Michael D. Schulz, Mariam S. Aboian, Mark W. Wilson, Terilynn Moore, Steven W. Hetts, Robert H. Grubbs
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Chemotherapy agents are prone to producing severe side-effects, and their sequestration prior to their entering of the circulatory system is thus highly desirable. Here, the authors functionalize iron oxide nanoparticles with genomic DNA and achieve
Externí odkaz:
https://doaj.org/article/23ea153931824599ac2105f9ce1a046a
Autor:
Ashley P Wright, Emily A Wyatt, Robert J Lamm, Carl M Blumenfeld, Jodi D Bradley, Gayatri Shrikhande, Timothy Hagerty
Publikováno v:
Cancer Research. 82:P2-13
Background: Nanoparticles (NPs) have been developed to enhance the pharmacokinetic (PK) and biodistribution characteristics of molecules. Many early NPs, including liposomes, dendrimers, and polymeric micelles, were limited in their ability to access
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acf9af18f82bc89af7e85ae02b5a5852
https://doi.org/10.1158/1538-7445.sabcs21-p2-13-09
https://doi.org/10.1158/1538-7445.sabcs21-p2-13-09
Publikováno v:
Cancer Research. 82:P5-16
Background: Here we introduce a novel nanoparticle therapeutic, DAN-222, which offers a variety of potential clinical benefits in delivery of chemotherapy versus native drug, including a broader therapeutic index. DAN-222 is a polymeric nanoparticle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b65a03f23177d1c88a6cdc87a5fe91
https://doi.org/10.1158/1538-7445.sabcs21-p5-16-16
https://doi.org/10.1158/1538-7445.sabcs21-p5-16-16
Autor:
Robert H. Grubbs, Carl M. Blumenfeld, Brendon J. McNicholas, Harry B. Gray, Jay R. Winkler, Wesley W. Kramer
Publikováno v:
Russian Journal of Electrochemistry. 53:1189-1193
Voltammetry of [5,10,15-tris(pentafluorophenylcorrole)]Mn(III) was investigated in four different ionic liquids (ILs): 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (BMIm-TFSI); 1-ethyl-3-methylimidazolium ethylsulfate (EMIm-EtOSO_3);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77da894ebb3924a753e7e12b22c0947a
https://doi.org/10.1134/s1023193517100068
https://doi.org/10.1134/s1023193517100068
Autor:
Robert H. Grubbs, Steven W. Hetts, Carl M. Blumenfeld, Terilynn Moore, Michael D. Schulz, Mark W. Wilson, Mariam Aboian
Publikováno v:
Nature communications, vol 9, iss 1
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Chemotherapy agents are notorious for producing severe side-effects. One approach to mitigating this off-target damage is to deliver the chemotherapy directly to a tumor via transarterial infusion, or similar procedures, and then sequestering any che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3807fd6132b9e71c7f069e5b6c9dd1b5
https://escholarship.org/uc/item/38q0n61c
https://escholarship.org/uc/item/38q0n61c
Autor:
Lawrence M. Henling, Scott C. Virgil, Harry B. Gray, Robert H. Grubbs, Katherine J. Fisher, Carl M. Blumenfeld
Publikováno v:
European Journal of Organic Chemistry. 2015:3022-3025
The mechanistic features of oligomerization and oxidative cyclization steps in the synthesis of tris(pentafluorophenyl)corrole (1) have been thoroughly studied. Separation of the intermediates by preparative HPLC and analysis by NMR spectroscopy and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490a3d144a77befa0fe03ab74f3e8a10
https://doi.org/10.1002/ejoc.201500276
https://doi.org/10.1002/ejoc.201500276
Autor:
Harry B. Gray, Bryce Sadtler, Robert H. Grubbs, G. Esteban Fernandez, Felix Alonso-Valenteen, Nathan S. Lewis, Cathie Nguyen, Rex Moats, Lily Dara, Lali K. Medina-Kauwe, Karn Sorasaenee, Carl M. Blumenfeld
Publikováno v:
Journal of Inorganic Biochemistry. 140:39-44
We are investigating the biological and biomedical imaging roles and impacts of fluorescent metallocorrole–TiO_2 nanoconjugates as potential near-infrared optical contrast agents in vitro in cancer and normal cell lines. The TiO_2 nanoconjugate lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f793e044812d2c113e2af2402db7f0d
https://doi.org/10.1016/j.jinorgbio.2014.06.015
https://doi.org/10.1016/j.jinorgbio.2014.06.015
Publikováno v:
Chemphyschem : a European journal of chemical physics and physical chemistry. 18(9)
Globally scalable sunlight-driven devices that convert solar energy into storable fuels will require efficient light absorbers that are made of non-precious elements. Suitable photoanode materials are yet to be discovered. Here we utilised the timesa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cec1ee247fd2ee3b73b6c779dafe2b
https://pubmed.ncbi.nlm.nih.gov/28095594
https://pubmed.ncbi.nlm.nih.gov/28095594
Autor:
Brian M. Hoffman, Carl M. Blumenfeld, Todd Wielgos, Prasad Dande, Anthony G. M. Barrett, Sharon Pokropinski, Ton That Hai, Evan R. Trivedi
Publikováno v:
Tetrahedron Letters. 53:5475-5478
We report the synthesis of the near infrared (NIR) fluorescent porphyrazine (Pz) 285, with pendant hydroxyl groups, as a non-toxic platform for delivery of conjugated chemotherapeutic agents to tumor cells. Conjugation of Pz 285 to Doxorubicin via an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aa4f6b578fc7dd926566f78989f1f32
https://doi.org/10.1016/j.tetlet.2012.07.087
https://doi.org/10.1016/j.tetlet.2012.07.087
Autor:
Carl M. Blumenfeld, Evan R. Trivedi, Brian M. Hoffman, Anthony G. M. Barrett, Hong Zong, Sangwan Lee
Publikováno v:
The Journal of Organic Chemistry. 75:1799-1802
In an effort to develop effective new optical contrast agents, we report the synthesis of porphyrazines (pzs) of the form H(2)[pz(A(4-n);C(n))], n = 1, and 2 (trans-), where "A" represents peripheral heteroatom (S- and O-) R-groups and "C" is a fused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3357c3acdb653248e2b5cddb921382e
https://doi.org/10.1021/jo9026947
https://doi.org/10.1021/jo9026947