Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Carl L. Roland"'
Autor:
Jane Loftus, Andrew Yaworsky, Carl L. Roland, Diane Turner-Bowker, Megan McLafferty, Sylvia Su, Roger E. Lamoureux
Publikováno v:
PLoS ONE, Vol 17, Iss 11 (2022)
Background Daily injections of recombinant human growth hormone are the standard of care to treat growth failure due to pediatric growth hormone deficiency (GHD). While effective, daily injections are burdensome and can compromise adherence. In recen
Externí odkaz:
https://doaj.org/article/92e324e772854a0c95d9448f97b50fa0
Autor:
Cheri L Deal, Joel Steelman, Elpis Vlachopapadopoulou, Renata Stawerska, Lawrence A Silverman, Moshe Phillip, Ho-Seong Kim, CheolWoo Ko, Oleg Malievskiy, Jose F Cara, Carl L Roland, Carrie Turich Taylor, Srinivas Rao Valluri, Michael P Wajnrajch, Aleksandra Pastrak, Bradley S Miller
Publikováno v:
The Journal of clinical endocrinology and metabolism. 107(7)
Context Somatrogon is a long-acting recombinant human growth hormone (rhGH) in development for once-weekly treatment of children with growth hormone deficiency (GHD). Objective We aimed to compare the efficacy and safety of once-weekly somatrogon wit
Autor:
Mario Mendoza, Michael Polson, Peter W. Park, Theodore J. Cicero, Sidney H. Schnoll, Lynn R. Webster, Carl L. Roland, Richard C. Dart, Jack Mardekian, Michael Cattaneo
Publikováno v:
Postgraduate Medicine. 131:225-229
Opioids with abuse-deterrent properties may reduce widespread abuse, misuse, and diversion of these products. This study aimed to quantify misuse, abuse, dependence, and health resource use of extended-release morphine sulfate with sequestered naltre
Publikováno v:
Journal of Managed Care & Specialty Pharmacy. 25:18-27
Reliance on prescription opioids to manage pain has been associated with increases in diversion, overdose, and addiction. Prevalence of misuse and abuse has been shown to be higher among government-insured populations than commercially insured popula
Autor:
Ho-Seong Kim, Oleg Malievskiy, Cheol Woo Ko, Bradley S. Miller, Elpis Vlachopapadopoulou, Cheri Deal, Joel Steelman, Carrie T. Taylor, John Choe, Michael Wajnrajch, Moshe Phillip, Carl L. Roland, Aleksandra Pastrak, Renata Stawerska, Lawrence A. Silverman, Srinivas Rao Valluri
Publikováno v:
Journal of the Endocrine Society. 5:A686-A687
Objectives: Somatrogon (hGH-CTP) is a long acting recombinant human growth hormone, consisting of the amino acid sequence of hGH and three copies of the carboxy-terminal peptide (CTP) of human chorionic gonadotropin (hCG) being developed as a once we
Autor:
Sherry Siegel, Jody M. Cleveland, James Brown, Carl L. Roland, Nathaniel P. Katz, Keung Lee, Linda Wase, Beatrice Setnik
Publikováno v:
Journal of Opioid Management. 7:467-483
Objectives: To evaluate potential for and incidence of aberrant drug-related behaviors among patients with chronic, moderate-to-severe pain in a primary care setting and to determine investigator compliance with universal precautions (UP) approach to
Autor:
Julia Quitmann, Srinivas Rao Valluri, Lawrence Reiter, Jane Loftus, Carl L. Roland, Aleksandra Pastrak
Publikováno v:
Journal of the Endocrine Society
Objective: Paediatric growth hormone deficiency (pGHD) affects 1/4,000 children. Treatment with daily sub-cutaneous injections of recombinant human growth hormone (r-hGH) increase height velocity and quality of life (QoL). A recent randomised control
Publikováno v:
Journal of Pain & Palliative Care Pharmacotherapy. 31:218-227
Prescription opioids are among the most effective analgesics to treat moderate to severe pain; however, little is known about the use of prescription opioids in children, particularly those receiving an extended-release formulation for the treatment
Publikováno v:
Postgraduate Medicine. 129:12-21
Objective: Prescription opioid misuse and abuse is a serious public health concern that can lead to overdose, addiction, and death. The development of opioid formulations designed to deter misuse and abuse is considered an important step towards addr
Autor:
Alan G. White, Zitong B Jia, Mario Mendoza, Mihran Ara Yenikomshian, Michael E Carson, Carl L. Roland
Publikováno v:
Journal of medical economics. 22(10)
Objectives: To extend a previously published manuscript on a model for estimating potential avoided medical events and cost savings in the US associated with the introduction of extended-release ab...