Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Carl K. Buckner"'
Autor:
Carl K. Buckner, Rand I. Fishleder, Frank M. Graziano, James A. Will, John K. Brendel, R. Conklin, J. Ro
Publikováno v:
Journal of Allergy and Clinical Immunology. 87:655-661
This study examined the possibility that there is cross-desensitization between immunologic and nonimmunologic stimuli that evoke contraction and histamine release (HR) in the isolated guinea pig trachea. Compound 48/80 and D-tubocurarine were found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb749a8e4a72ba04eca32bcf94f00b4
https://doi.org/10.1016/0091-6749(91)90384-z
https://doi.org/10.1016/0091-6749(91)90384-z
Publikováno v:
Inflammation. 18(1)
Guinea pig lung mast cells can be isolated and purified to high purity. This has given us the opportunity to study in greater detail mediator release from these cells. Both immunologic (ovalbumin sensitized) and nonimmunologic (calcium ionophore, CaI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00320dad47111be516d7d1563381ae18
https://pubmed.ncbi.nlm.nih.gov/7515858
https://pubmed.ncbi.nlm.nih.gov/7515858
Autor:
David Aharony, Edward J. Kusner, Kathleen L. Neilson, Carl K. Buckner, Laura A. Cronk, Karin Kirkland, Robert T. Jacobs, Frederick J. Brown
Publikováno v:
Journal of medicinal chemistry. 36(3)
Substituted indole-5-carboxamides and indole-6-carboxamides have been found to be potent and selective antagonists of the peptidoleukotrienes. Initial derivatives of these series (4-[[5-[(cyclopentylmethyl)carbamoyl]-1-methylindol-3-yl] methyl]-3-met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024e2ccf1193153bfc4a3a527139166b
https://pubmed.ncbi.nlm.nih.gov/8381184
https://pubmed.ncbi.nlm.nih.gov/8381184
Publikováno v:
The Journal of allergy and clinical immunology. 87(6)
We have previously reported differences in mediator release during equivalent levels of antigen (Ag)-induced smooth muscle contraction of guinea pig pulmonary tissues after passive sensitization with IgG1 versus IgE antibodies (Abs). In the present s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721e4609105f5d7445c1f9afce731356
https://pubmed.ncbi.nlm.nih.gov/1710633
https://pubmed.ncbi.nlm.nih.gov/1710633
Autor:
David W. Snyder, Barrie Hesp, Ralph E. Giles, R D Krell, Bernstein Peter Robert, Richard A. Keith, Victor Giulio Matassa, Carl K. Buckner, Edward J. Kusner, Fred J. Brown, David Aharony, Ying K. Yee
Publikováno v:
The American review of respiratory disease. 141(4 Pt 1)
ICI 204,219 (4-(5-cyclopentyloxycarbonylamino-1-methylindol-3-ylmethy l)-3- methoxy-N-o-tolylsulfonylbenzamide) was designed as a peptide leukotriene (LT) antagonist. The compound is a competitive antagonist of LTD4- and LTE4-induced contraction of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfa449e2f0389638f9bad52e39c8beb
https://pubmed.ncbi.nlm.nih.gov/2158259
https://pubmed.ncbi.nlm.nih.gov/2158259
Autor:
Frank M. Graziano, Elliot C. Dick, Thomas Mullins, Robin Tilton, David Segaloff, Carl K. Buckner, Thomas Hirth, William W. Busse
Publikováno v:
American Review of Respiratory Disease. 139:715-720
The guinea pig infected with parainfluenza 3 (P-3) has provided an animal model to study mechanisms of virus-induced asthma and airway hyperreactivity. Evidence to identify the mechanisms by which P-3 infection enhances airway hyperreactivity, howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de8af0d40eca83da50d091fc1ad293f
https://doi.org/10.1164/ajrccm/139.3.715
https://doi.org/10.1164/ajrccm/139.3.715
Autor:
Joseph Chang, R. P. Carlson, C. Tio, T. J. Forster, W. C. Daniel, Carl K. Buckner, S. F. Sisenwine, B. J. Undem, Alan J. Lewis, J. M. Hand
Publikováno v:
Agents and Actions. 18:306-312
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88545b8f1606831d97920e904954ab81
https://doi.org/10.1007/bf01964989
https://doi.org/10.1007/bf01964989
Publikováno v:
European Journal of Pharmacology. 76:439-442
Leukotrienes C4 (LTC) and D4 (LTD) produced contractions of the isolated guinea-pig pulmonary arteries, but were much less potent in these segments than in the isolated trachea and parenchymal strip from the same species. Among the arterial segments,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f7c8029d70c509e2b0c1498d4fe22e
https://doi.org/10.1016/0014-2999(81)90118-7
https://doi.org/10.1016/0014-2999(81)90118-7
Publikováno v:
Journal of Immunological Methods. 81:187-197
Pulmonary mast cells were obtained from guinea pig lung using a combination of enzymatic digestion of tissue, centrifugal elutriation, and density gradient centrifugation on Percoll. In the initial procedure, lung tissue was enzymatically digested wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68604fe3427460cf020ab82f5ddee67
https://doi.org/10.1016/0022-1759(85)90203-0
https://doi.org/10.1016/0022-1759(85)90203-0
Publikováno v:
European Journal of Pharmacology. 47:259-271
Increasing concentrations of the functional antagonist carbachol resulted in a shift to the right of the dose-response curves for (--)-isoproterenol-induced positive chronotropic and inotropic responses and a reduction of the maximum degree of respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8594f4522cfe492b32ccd02b1d2d72
https://doi.org/10.1016/0014-2999(78)90233-9
https://doi.org/10.1016/0014-2999(78)90233-9