Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Carl J, Heneghan"'
Autor:
Oghenekome A. Gbinigie, Anne-Marie Boylan, Christopher C. Butler, Carl J. Heneghan, Sarah Tonkin-Crine
Publikováno v:
BMC Primary Care, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Opportunistic recruitment in primary care is challenging due to the inherent unpredictability of incident conditions, and workload and time pressures. Many clinical trials do not recruit to target, leading to equivocal answers to
Externí odkaz:
https://doaj.org/article/d00d5b8fa11f4a2db5f435a47147aada
Autor:
Carl J. Heneghan, Igho J. Onakpoya, Tom Jefferson, David H. Evans, Annette Plüddemann, John M. Conly, Elizabeth A. Spencer, Jon Brassey
Publikováno v:
F1000Research, Vol 10 (2022)
Background: SARS-CoV-2 transmission has been reported to be associated with close contact with infected individuals. However, the mechanistic pathway for transmission in close contact settings is unclear. Our objective was to identify, appraise and s
Externí odkaz:
https://doaj.org/article/f5212812ca0841379ae999e1c4768d4d
Autor:
Carl J. Heneghan, Igho J. Onakpoya, Tom Jefferson, David H. Evans, Annette Plüddemann, John M. Conly, Elizabeth A. Spencer, Jon Brassey
Publikováno v:
F1000Research, Vol 10 (2022)
Background: SARS-CoV-2 transmission has been reported to be associated with close contact with infected individuals. However, the mechanistic pathway for transmission in close contact settings is unclear. Our objective was to identify, appraise and s
Externí odkaz:
https://doaj.org/article/3761fa8db8284dd9a14837febee7ba59
Autor:
Georgia C. Richards, Kamal R. Mahtani, Tonny B. Muthee, Nicholas J. DeVito, Constantinos Koshiaris, Jeffrey K. Aronson, Ben Goldacre, Carl J. Heneghan
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background The risks of harms from opioids increase substantially at high doses, and high-dose prescribing has increased in primary care. However, little is known about what leads to high-dose prescribing, and studies exploring this have not
Externí odkaz:
https://doaj.org/article/41f42a34a7c549e7b5c1aed0e6760059
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0266202 (2022)
BackgroundThe optimal time for initiation of dialysis and which modality to choose as the starting therapy is currently unclear. This systematic review aimed to assess the recommendations across high-quality clinical practice guidelines (CPGs) relate
Externí odkaz:
https://doaj.org/article/1401770932ff4ee8b9fc03526a9d0c70
Autor:
Tom Jefferson, John M. Conly, David H. Evans, Carl J. Heneghan, Igho J. Onakpoya, Annette Plüddemann, Jon Brassey, Elizabeth A. Spencer
Publikováno v:
F1000Research, Vol 10 (2021)
Background: Modes of transmission of SARS-CoV-2 are of key public health importance. SARS-CoV-2 has been detected in the feces of some COVID-19 patients, suggesting the possibility that the virus could, in addition to droplet and fomite transmission,
Externí odkaz:
https://doaj.org/article/70cf2cdb77f341b19cd3c207afe1811f
Autor:
Oghenekome A. Gbinigie, Igho J. Onakpoya, Georgia C. Richards, Elizabeth A. Spencer, Constantinos Koshiaris, Niklas Bobrovitz, Carl J. Heneghan
Publikováno v:
BMC Geriatrics, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background The value of biomarkers for diagnosing bacterial infections in older outpatients is uncertain and limited official guidance exists for clinicians in this area. The aim of this review is to critically appraise and evaluate biomarke
Externí odkaz:
https://doaj.org/article/b4a1446c156b4279a28251835b1fbee0
Autor:
Oghenekome A. Gbinigie, José M. Ordóñez-Mena, Thomas Fanshawe, Annette Plüddemann, Carl J. Heneghan
Publikováno v:
BMC Geriatrics, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Older adults with bacterial skin infections may present with atypical symptoms, making diagnosis difficult. There is limited authoritative guidance on how older adults in the community present with bacterial skin infections. To da
Externí odkaz:
https://doaj.org/article/51280e0796eb4a669c5aa62d4f3bf16c
Autor:
Igho J. Onakpoya, Carl J. Heneghan, Elizabeth A. Spencer, Jon Brassey, Annette Plüddemann, David H. Evans, John M. Conly, Tom Jefferson
Publikováno v:
F1000Research, Vol 10 (2021)
Background: SARS-CoV-2 RNA has been detected in fomites which suggests the virus could be transmitted via inanimate objects. However, there is uncertainty about the mechanistic pathway for such transmissions. Our objective was to identify, appraise a
Externí odkaz:
https://doaj.org/article/0f20d51571d14c9f9d6fa8bb9ebdafb0
Autor:
Igho J. Onakpoya, Carl J. Heneghan, Elizabeth A. Spencer, Jon Brassey, Annette Plüddemann, David H. Evans, John M. Conly, Tom Jefferson
Publikováno v:
F1000Research, Vol 10 (2021)
Background: SARS-CoV-2 RNA has been detected in fomites which suggests the virus could be transmitted via inanimate objects. However, there is uncertainty about the mechanistic pathway for such transmissions. Our objective was to identify, appraise a
Externí odkaz:
https://doaj.org/article/6b636eedd53446aea460264cbbf54f9f