Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Carl Harrison"'
1
Akademický článek
True Molecular Scale Visualization of Variable Clustering Properties of Ryanodine Receptors
Autor: Isuru Jayasinghe, Alexander H. Clowsley, Ruisheng Lin, Tobias Lutz, Carl Harrison, Ellen Green, David Baddeley, Lorenzo Di Michele, Christian Soeller
Publikováno v: Cell Reports, Vol 22, Iss 2, Pp 557-567 (2018)
Summary: Signaling nanodomains rely on spatial organization of proteins to allow controlled intracellular signaling. Examples include calcium release sites of cardiomyocytes where ryanodine receptors (RyRs) are clustered with their molecular partners
Externí odkaz: https://doaj.org/article/16126721d7004c8086a4dbcafdb5274d
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2
Akademický článek
Cellular and Molecular Anatomy of the Human Neuromuscular Junction
Autor: Ross A. Jones, Carl Harrison, Samantha L. Eaton, Maica Llavero Hurtado, Laura C. Graham, Leena Alkhammash, Oladayo A. Oladiran, Andy Gale, Douglas J. Lamont, Hamish Simpson, Martin W. Simmen, Christian Soeller, Thomas M. Wishart, Thomas H. Gillingwater
Publikováno v: Cell Reports, Vol 21, Iss 9, Pp 2348-2356 (2017)
The neuromuscular junction (NMJ) plays a fundamental role in transferring information from lower motor neuron to skeletal muscle to generate movement. It is also an experimentally accessible model synapse routinely studied in animal models to explore
Externí odkaz: https://doaj.org/article/5086088e376444649f55ca61fbb71150
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3
Akademický článek
Direct Comparison of Rat- and Human-Derived Ganglionic Eminence Tissue Grafts on Motor Function
Autor: Mariah J. Lelos, Victoria H. Roberton, Ngoc-Nga Vinh, Carl Harrison, Peter Eriksen, Eduardo M. Torres, Susanne P. Clinch, Anne E. Rosser, Stephen B. Dunnett
Publikováno v: Cell Transplantation, Vol 25 (2016)
Huntington's disease (HD) is a debilitating, genetically inherited neurodegenerative disorder that results in early loss of medium spiny neurons from the striatum and subsequent degeneration of cortical and other subcortical brain regions. Behavioral
Externí odkaz: https://doaj.org/article/df23e504e51b433fba2083b61469edff
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5
Molecular mechanisms mediating asymmetric subcellular localisation of the core planar polarity pathway proteins
Autor: Hongyu Shao, Carl Harrison, Helen Strutt, David Strutt
Publikováno v: Biochemical Society Transactions
Planar polarity refers to cellular polarity in an orthogonal plane to apicobasal polarity, and is seen across scales from molecular distributions of proteins to tissue patterning. In many contexts it is regulated by the evolutionarily conserved ‘co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65dcbcfc048304ee0cb06738017c7936
https://doi.org/10.1042/bst20190404
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