Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Carl Graham"'
Autor:
Jeffrey Seow, Zayed A. Shalim, Carl Graham, Simon Kimuda, Aswin Pillai, Thomas Lechmere, Ashwini Kurshan, Atika M. Khimji, Luke B. Snell, Gaia Nebbia, Christine Mant, Anele Waters, Julie Fox, Michael H. Malim, Katie J. Doores
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Despite the success of COVID-19 vaccines in preventing infection and/or severe disease, there has been an increase in SARS-CoV-2 infections in vaccinated individuals owing to the waning vaccine-derived immunity, and the emergence of new vari
Externí odkaz:
https://doaj.org/article/81c408cdde124becb570e71f189dd88d
Autor:
Nathan J Cheetham, Milla Kibble, Andrew Wong, Richard J Silverwood, Anika Knuppel, Dylan M Williams, Olivia KL Hamilton, Paul H Lee, Charis Bridger Staatz, Giorgio Di Gessa, Jingmin Zhu, Srinivasa Vittal Katikireddi, George B Ploubidis, Ellen J Thompson, Ruth CE Bowyer, Xinyuan Zhang, Golboo Abbasian, Maria Paz Garcia, Deborah Hart, Jeffrey Seow, Carl Graham, Neophytos Kouphou, Sam Acors, Michael H Malim, Ruth E Mitchell, Kate Northstone, Daniel Major-Smith, Sarah Matthews, Thomas Breeze, Michael Crawford, Lynn Molloy, Alex SF Kwong, Katie Doores, Nishi Chaturvedi, Emma L Duncan, Nicholas J Timpson, Claire J Steves
Publikováno v:
eLife, Vol 12 (2023)
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody levels can be used to assess humoral immune responses following SARS-CoV-2 infection or vaccination, and may predict risk of future infection. Higher levels of SARS-CoV
Externí odkaz:
https://doaj.org/article/3b470fcd4a024f3f9f98813d3730e991
Autor:
Carl Graham, Thomas Lechmere, Aisha Rehman, Jeffrey Seow, Ashwini Kurshan, Isabella Huettner, Thomas J A Maguire, Jerry C H Tam, Daniel Cox, Christopher Ward, Mariusz Racz, Anele Waters, Christine Mant, Michael H Malim, Julie Fox, Katie J Doores
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010882 (2022)
COVID-19 vaccines are playing a vital role in controlling the COVID-19 pandemic. As SARS-CoV-2 variants encoding mutations in the surface glycoprotein, Spike, continue to emerge, there is increased need to identify immunogens and vaccination regimens
Externí odkaz:
https://doaj.org/article/38e17544a9d446ba9acc595cb5f39fb8
Autor:
Jeffrey Seow, Carl Graham, Sadie R. Hallett, Thomas Lechmere, Thomas J.A. Maguire, Isabella Huettner, Daniel Cox, Hataf Khan, Suzanne Pickering, Rebekah Roberts, Anele Waters, Christopher C. Ward, Christine Mant, Michael J. Pitcher, Jo Spencer, Julie Fox, Michael H. Malim, Katie J. Doores
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110757- (2022)
Summary: Although the antibody response to COVID-19 vaccination has been studied extensively at the polyclonal level using immune sera, little has been reported on the antibody response at the monoclonal level. Here, we isolate a panel of 44 anti-SAR
Externí odkaz:
https://doaj.org/article/c8a108ba74b346e4ac6cb60515b0c6d2
Autor:
Ceri Alan Fielding, Pragati Sabberwal, James C Williamson, Edward JD Greenwood, Thomas WM Crozier, Wioleta Zelek, Jeffrey Seow, Carl Graham, Isabella Huettner, Jonathan D Edgeworth, David A Price, Paul B Morgan, Kristin Ladell, Matthias Eberl, Ian R Humphreys, Blair Merrick, Katie Doores, Sam J Wilson, Paul J Lehner, Eddie CY Wang, Richard J Stanton
Publikováno v:
eLife, Vol 11 (2022)
The outcome of infection is dependent on the ability of viruses to manipulate the infected cell to evade immunity, and the ability of the immune response to overcome this evasion. Understanding this process is key to understanding pathogenesis, genet
Externí odkaz:
https://doaj.org/article/dac3657f8bfc48e98d71a0036c060efa
Autor:
Thomas Lechmere, Luke B. Snell, Carl Graham, Jeffrey Seow, Zayed A. Shalim, Themoula Charalampous, Adela Alcolea-Medina, Rahul Batra, Gaia Nebbia, Jonathan D. Edgeworth, Michael H. Malim, Katie J. Doores
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Numerous studies have shown that a prior SARS-CoV-2 infection can greatly enhance the antibody response to COVID-19 vaccination, with this so called “hybrid immunity” leading to greater neutralization breadth against SARS-CoV-2 variants
Externí odkaz:
https://doaj.org/article/532af9eb26d2434498e1ed5b78f8f9bd
Autor:
Sultan Abdul-Jawad, Richard Beatson, Thomas Lechmere, Rosalind Graham, Thanussuyah Alaguthurai, Carl Graham, Jennifer Vidler, Austin Kulasekararaj, Piers E.M. Patten, Katie J. Doores, Sheeba Irshad
Publikováno v:
Haematologica, Vol 107, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/785d657b64254ba793a592c161d71b42
Autor:
Hataf Khan, Helena Winstone, Jose M Jimenez-Guardeño, Carl Graham, Katie J Doores, Caroline Goujon, David A Matthews, Andrew D Davidson, Suzannah J Rihn, Massimo Palmarini, Stuart J D Neil, Michael H Malim
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009820 (2021)
Interferons play a critical role in regulating host immune responses to SARS-CoV-2, but the interferon (IFN)-stimulated gene (ISG) effectors that inhibit SARS-CoV-2 are not well characterized. The IFN-inducible short isoform of human nuclear receptor
Externí odkaz:
https://doaj.org/article/cc928219677448eabb1717d19393c336
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 5, Pp 5120-5133 (2020)
We revisit the modeling of the diauxic growth of a pure microorganism on two distinct sugars which was first described by Monod. Most available models are deterministic and make the assumption that all cells of the microbial ecosystem behave homogene
Externí odkaz:
https://doaj.org/article/05ab98dd458e42ca9ced1a6759c24177
Autor:
Chloe Rees-Spear, Luke Muir, Sarah A. Griffith, Judith Heaney, Yoann Aldon, Jonne L. Snitselaar, Peter Thomas, Carl Graham, Jeffrey Seow, Nayung Lee, Annachiara Rosa, Chloe Roustan, Catherine F. Houlihan, Rogier W. Sanders, Ravindra K. Gupta, Peter Cherepanov, Hans J. Stauss, Eleni Nastouli, Katie J. Doores, Marit J. van Gils, Laura E. McCoy
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108890- (2021)
Summary: Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines show protective efficacy, which is most likely mediated by neutralizing antibodies recognizing the viral entry protein, spike. Because new SARS-CoV-2 variants are
Externí odkaz:
https://doaj.org/article/78e75387f25c4488ad981560e9ef8e93