Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Carl Goodyear"'
Autor:
Iain B McInnes, Stefan Siebert, Paul Bowness, Laura C Coates, Anne Francis, Bruce W Kirkham, Alexander Ooms, Hussein Al-Mossawi, Louise Bennett, Nicole Yager, Duncan Richards, Mimi Bogale, Carl Goodyear, Sylvine Lalnunhlimi, Leonie S Taams, Aysin Tulunay Virlan
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Introduction Psoriatic arthritis (PsA) affects around 150 000 people in the UK of whom around 50% require treatment with biologics. The most used biologics for PsA target tumour necrosis factor (TNF) or interleukin-17A (IL-17A). About 50% of patients
Externí odkaz:
https://doaj.org/article/fec1e3e94bdb470b8bf658b6414ae65c
Autor:
Katerina Miari, Athanasia Papadopoulou, Leandro Martinez, Victoria Campbell, Carl Goodyear, Helen Wheadon, Monica Guzman, Mark Williams
Publikováno v:
HemaSphere, Vol 7, p e92103ee (2023)
Externí odkaz:
https://doaj.org/article/835e6afba0ab4b3881c7cacc21455986
Autor:
John J. Cole, Alison McColl, Robin Shaw, Mary-Ellen Lynall, Philip J. Cowen, Peter de Boer, Wayne C. Drevets, Neil Harrison, Carmine Pariante, Linda Pointon, NIMA consortium, Carl Goodyear, Edward Bullmore, Jonathan Cavanagh
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The increasingly compelling data supporting the involvement of immunobiological mechanisms in Major Depressive Disorder (MDD) might provide some explanation forthe variance in this heterogeneous condition. Peripheral blood measures of cytoki
Externí odkaz:
https://doaj.org/article/4f30ee2b03a34839b646dd4197288e34
Autor:
Robert Gurke, Annika Bendes, John Bowes, Michaela Koehm, Richard M. Twyman, Anne Barton, Dirk Elewaut, Carl Goodyear, Lisa Hahnefeld, Rainer Hillenbrand, Ewan Hunter, Mark Ibberson, Vassilios Ioannidis, Sabine Kugler, Rik J. Lories, Eduard Resch, Stefan Rüping, Klaus Scholich, Jochen M. Schwenk, James C. Waddington, Phil Whitfield, Gerd Geisslinger, Oliver FitzGerald, Frank Behrens, Stephen R. Pennington
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2387 (2022)
The definitive diagnosis and early treatment of many immune-mediated inflammatory diseases (IMIDs) is hindered by variable and overlapping clinical manifestations. Psoriatic arthritis (PsA), which develops in ~30% of people with psoriasis, is a key e
Externí odkaz:
https://doaj.org/article/8ed947e41a664f22a2b952f33211051f
Autor:
Graeme J. M. Cowan, Katherine Miles, Lorenzo Capitani, Sophie S. B. Giguere, Hanna Johnsson, Carl Goodyear, Iain B. McInnes, Steffen Breusch, David Gray, Mohini Gray
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
B cells are critical for promoting autoimmunity and the success of B cell depletion therapy in rheumatoid arthritis (RA) confirms their importance in driving chronic inflammation. Whilst disease specific autoantibodies are useful diagnostically, our
Externí odkaz:
https://doaj.org/article/0e48b0fffc664e8ba6b84de7f262ee22
Autor:
Sally A, Clayton, Kalbinder K, Daley, Lucy, MacDonald, Erika, Fernandez-Vizarra, Giovanni, Bottegoni, John D, O'Neil, Triin, Major, Daniel, Griffin, Qinqin, Zhuang, Adeolu B, Adewoye, Kieran, Woolcock, Simon W, Jones, Carl, Goodyear, Aziza, Elmesmari, Andrew, Filer, Daniel A, Tennant, Stefano, Alivernini, Christopher D, Buckley, Robert D S, Pitceathly, Mariola, Kurowska-Stolarska, Andrew R, Clark
Publikováno v:
Science Advances
Description
Exchange of mitochondrial subunits C15ORF48 and NDUFA4 occurs during macrophage activation in vitro and in inflammatory disease.
Dysregulated mitochondrial function is a hallmark of immune-mediated inflammatory diseases. Cytochr
Exchange of mitochondrial subunits C15ORF48 and NDUFA4 occurs during macrophage activation in vitro and in inflammatory disease.
Dysregulated mitochondrial function is a hallmark of immune-mediated inflammatory diseases. Cytochr
Autor:
Sam Murray, Stephanie Longet, Tom Tipton, Maria Carlota Londoño, Elisa Pose, Stephen Laidlaw, Dung Nguyen, Georgina Meacham, Zixiang Lim, Stavros Dimitriadis, Sophie Irwin, Jonathan Cook, Massimo Iavarone, Pietro Lampertico, Virginia Hernandez-Gea, Juan Carlos Garcia Pagan, Julian Schulze zur Wiesch, Martina Sterneck, Francesco Paolo Russo, Jack Satsangi, Susanna Dunachie, Paul Klenerman, Carl Goodyear, Iain B. McInnes, Pere Ginès, Miles Carroll, Thomas Marjot, Eleanor Barnes
Publikováno v:
Journal of Hepatology. 77:S57
Autor:
Verena, Kästele, Johannes, Mayer, Edward S, Lee, Natalie, Papazian, John J, Cole, Vuk, Cerovic, Gabrielle, Belz, Michio, Tomura, Gerard, Eberl, Carl, Goodyear, Rose A, Maciewicz, Daniel, Wall, Tom, Cupedo, David R, Withers, Simon, Milling
Publikováno v:
Mucosal immunology. 14(3)
Innate lymphoid cells (ILCs) are enriched in mucosae and have been described as tissue-resident. Interestingly, ILCs are also present within lymph nodes (LNs), in the interfollicular regions, the destination for lymph-migratory cells. We have previou
Publikováno v:
Advances in experimental medicine and biology. 1205
Rheumatoid arthritis (RA) affects around 1% of the population, which places a heavy burden on society and has severe consequences for the individuals affected. The early diagnosis and implementation of disease-modifying anti-rheumatic drugs significa
Autor:
Martijn van den Bosch, Irene DI Ceglie, Arjen Blom, Robab Davar, Colin Logie, Ehsan Habibi, Johannes Roth, Thomas Vogl, Carl Goodyear, Peter van der Kraan, Peter van Lent
Publikováno v:
Oral Presentations.