Zobrazeno 1 - 10 of 213 pro vyhledávání: '"Carl G. A. Persson"'
1
Airways exudation of plasma macromolecules: Innate defense, epithelial regeneration, and asthma
Autor: Carl G. A. Persson
Publikováno v: The Journal of Allergy and Clinical Immunology
This review discusses in vivo airway aspects of plasma exudation in relation to current views on epithelial permeability and epithelial regeneration in health and disease. Microvascular-epithelial exudation of bulk plasma proteins characteristically
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed57dcbeb7686fb840242f8a7687356
https://doi.org/10.1016/j.jaci.2018.07.037
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2
‘Bedside’ observations challenge aspects of the ‘epithelial barrier hypothesis’
Autor: Carl G. A. Persson
Publikováno v: Nature Reviews Immunology. 21:829-829
Correspondence regarding the Review ‘Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?'
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::194f7895417fa11a2132ed4c847a3a68
https://doi.org/10.1038/s41577-021-00650-8
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3
Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation
Autor: Leif Bjermer, Lena Uller, Hamid Akbarshahi, Carl G. A. Persson, Mandy Menzel, Ellen Tufvesson
Publikováno v: Oncotarget
// Mandy Menzel 1 , Hamid Akbarshahi 1 , Ellen Tufvesson 2 , Carl Persson 3 , Leif Bjermer 2 , Lena Uller 1 1 Respiratory Immunopharmacology, Department of Experimental Medical Science, Lund University, 22184 Lund, Sweden 2 Respiratory Medicine and A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e632034fe7023d96af98685bc85097e9
https://doi.org/10.18632/oncotarget.16364
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5
Viral induced overproduction of epithelial TSLP: Role in exacerbations of asthma and COPD?
Autor: Lena Uller, Carl G. A. Persson
Publikováno v: The Journal of Allergy and Clinical Immunology
Viral respiratory tract infections are associated with asthma inception in early life and asthma exacerbations in older children and adults. Although how viruses influence asthma inception is poorly understood, much research has focused on the host r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2414e25a6633e2e98d07f1d7c4bd7552
https://pubmed.ncbi.nlm.nih.gov/28987220
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6
Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy
Autor: Carl G. A. Persson
Publikováno v: European Respiratory Journal. 43:1208-1211
To the Editor: I read with interest the report by Davis et al. [1] on epithelial injury-shedding in vivo caused by tobacco smoke. Their model involves airways equipped with human-like subepithelial microvessels carrying systemic blood. By contrast, m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7200d66e3645f84775c01756d788619e
https://doi.org/10.1183/09031936.00099913
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8
In vivoobservations provide insight into roles of eosinophils and epithelial cells in asthma
Autor: Carl G. A. Persson
Publikováno v: European Respiratory Journal. 54:1900470
Observationsin vivoin patients, supported by guinea-pigin vivodata, take centre stage in this perspective. Its objective is to highlight dichotomies between asthma features observedin vivoand accepted views involving cell/molecular biology research p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcd40405036f6a7b0122038248ff9a50
https://doi.org/10.1183/13993003.00470-2019
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9
Selective inhibition by simvastatin of IRF3 phosphorylation and TSLP production in dsRNA-challenged bronchial epithelial cells from COPD donors
Autor: Leif Bjermer, Jenny Calvén, Angelica Brandelius, Morgan Andersson, Carl G. A. Persson, Irma Mahmutovic Persson, Lena Uller
Publikováno v: British Journal of Pharmacology. 168:363-374
Background and purpose: Statin treatment may ameliorate viral infection-induced exacerbations of chronic obstructive pulmonary disease (COPD), which exhibit Th2-type bronchial inflammation. Thymic stromal lymphopoietin (TSLP), a hub cytokine switchin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2daacf09cb2a6ff504178101a86eabf3
https://doi.org/10.1111/j.1476-5381.2012.02131.x
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10
Resolution of leucocyte-mediated mucosal diseases. A novel in vivo paradigm for drug development
Autor: Carl G. A. Persson, Lena Uller
Publikováno v: British Journal of Pharmacology. 165:2100-2109
Removal of disease-driving inflammatory leucocytes is central to resolution of inflammation. The current pharmacological dogma teaches leucocyte elimination through apoptosis followed by phagocytosis. However, actual resolving roles of apoptotic–ph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5dba5d3fde23e9a2cd4f30d04fa99e7b
https://doi.org/10.1111/j.1476-5381.2011.01772.x
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