Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Carl G Simon"'
Autor:
Greta Babakhanova, Stephen M Zimmerman, Laura T Pierce, Sumona Sarkar, Nicholas J Schaub, Carl G Simon
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262119 (2022)
Cell viability, an essential measurement for cell therapy products, lacks traceability. One of the most common cell viability tests is trypan blue dye exclusion where blue-stained cells are counted via brightfield imaging. Typically, live and dead ce
Externí odkaz:
https://doaj.org/article/9bd83a9bf57743d184df5c9906476482
Autor:
Carl G. Simon, Erich H. Bozenhardt, Christina M. Celluzzi, David Dobnik, Melanie L. Grant, Uma Lakshmipathy, Thiana Nebel, Linda Peltier, Anthony Ratcliffe, James L. Sherley, Glyn N. Stacey, Rouzbeh R. Taghizadeh, Eddie H. P. Tan, Sandrine Vessillier
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract One of the most challenging aspects of developing advanced cell therapy products (CTPs) is defining the mechanism of action (MOA), potency and efficacy of the product. This perspective examines these concepts and presents helpful ways to thi
Externí odkaz:
https://doaj.org/article/1a4c1b7ac9dd4b808e25bb9e5b77ce01
Autor:
Nathan A Hotaling, Jun Jeon, Mary Beth Wade, Derek Luong, Xavier-Lewis Palmer, Kapil Bharti, Carl G Simon
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167664 (2016)
An estimated $7.1 billion dollars a year is spent due to irreproducibility in pre-clinical data from errors in data analysis and reporting. Therefore, developing tools to improve measurement comparability is paramount. Recently, an open source tool,
Externí odkaz:
https://doaj.org/article/ca5ef2d191d445639e66e0d22371134f
Autor:
Reut Shainer, Vardit Kram, Tina M. Kilts, Li Li, Andrew D. Doyle, Inbal Shainer, Daniel Martin, Carl G. Simon, Jinyang Zeng-Brouwers, Liliana Schaefer, Marian F. Young, Genomics and Computational Biology Core
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Endochondral bone development and regeneration relies on activation and proliferation of periosteum derived-cells (PDCs). Biglycan (Bgn), a small proteoglycan found in extracellular matrix, is known to be expressed in bone and cartilage, however litt
Externí odkaz:
https://doaj.org/article/c2bea9f8a1d244e5b70587745ea890de
Publikováno v:
Fibers, Vol 11, Iss 5, p 39 (2023)
Electrospinning is a versatile tool used to produce highly customizable nonwoven nanofiber mats of various fiber diameters, pore sizes, and alignment. It is possible to create electrospun mats from synthetic polymers, biobased polymers, and combinati
Externí odkaz:
https://doaj.org/article/5c42153d52de4f239f8e0a59a108f01a
Autor:
Stephanie J, Florczyk, Nathan A, Hotaling, Mylene, Simon, Joe, Chalfoun, Allison L, Horenberg, Nicholas J, Schaub, Dongbo, Wang, Piotr M, Szczypiński, Veronica L, DeFelice, Peter, Bajcsy, Carl G, Simon
Publikováno v:
Journal of Biomedical Materials Research Part A. 111:106-117
The properties and structure of the cellular microenvironment can influence cell behavior. Sites of cell adhesion to the extracellular matrix (ECM) initiate intracellular signaling that directs cell functions such as proliferation, differentiation, a
Autor:
Greta Babakhanova, Anant Agrawal, Deepika Arora, Allison Horenberg, Jagat B. Budhathoki, Joy P. Dunkers, Joe Chalfoun, Peter Bajcsy, Carl G. Simon
Publikováno v:
Journal of Biomedical Materials Research Part A.
Publikováno v:
Data in Brief, Vol 5, Iss C, Pp 13-22 (2015)
DiameterJ is an open source image analysis plugin for ImageJ. DiameterJ produces ten files for every image that it analyzes. These files include the images that were analyzed, the data to create histograms of fiber radius, pore size, fiber orientatio
Externí odkaz:
https://doaj.org/article/ded7eabaf54c4bed92a175bf036bf7a5
Autor:
Stephanie J. Florczyk, Nathan A. Hotaling, Mylene Simon, Joe Chalfoun, Allison L. Horenberg, Nicholas J. Schaub, Dongbo Wang, Piotr M. Szczypiński, Veronica L. DeFelice, Peter Bajcsy, Carl G. Simon
Publikováno v:
Journal of Biomedical Materials Research Part A. 111
Publikováno v:
ACS Biomaterials Science & Engineering. 6:5368-5376
A metrological perspective for thinking about the characterization of tissue engineered medical products (TEMPs) may help improve communication between researchers. During the development lifecycle of a TEMP, many product properties are measured over