Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Carl G, Simon"'
Autor:
Carl G. Simon, Erich H. Bozenhardt, Christina M. Celluzzi, David Dobnik, Melanie L. Grant, Uma Lakshmipathy, Thiana Nebel, Linda Peltier, Anthony Ratcliffe, James L. Sherley, Glyn N. Stacey, Rouzbeh R. Taghizadeh, Eddie H. P. Tan, Sandrine Vessillier
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract One of the most challenging aspects of developing advanced cell therapy products (CTPs) is defining the mechanism of action (MOA), potency and efficacy of the product. This perspective examines these concepts and presents helpful ways to thi
Externí odkaz:
https://doaj.org/article/1a4c1b7ac9dd4b808e25bb9e5b77ce01
Autor:
Reut Shainer, Vardit Kram, Tina M. Kilts, Li Li, Andrew D. Doyle, Inbal Shainer, Daniel Martin, Carl G. Simon, Jinyang Zeng-Brouwers, Liliana Schaefer, Marian F. Young, Genomics and Computational Biology Core
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Endochondral bone development and regeneration relies on activation and proliferation of periosteum derived-cells (PDCs). Biglycan (Bgn), a small proteoglycan found in extracellular matrix, is known to be expressed in bone and cartilage, however litt
Externí odkaz:
https://doaj.org/article/c2bea9f8a1d244e5b70587745ea890de
Publikováno v:
Fibers, Vol 11, Iss 5, p 39 (2023)
Electrospinning is a versatile tool used to produce highly customizable nonwoven nanofiber mats of various fiber diameters, pore sizes, and alignment. It is possible to create electrospun mats from synthetic polymers, biobased polymers, and combinati
Externí odkaz:
https://doaj.org/article/5c42153d52de4f239f8e0a59a108f01a
Autor:
Greta Babakhanova, Stephen M. Zimmerman, Laura T. Pierce, Sumona Sarkar, Nicholas J. Schaub, Carl G. Simon
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Cell viability, an essential measurement for cell therapy products, lacks traceability. One of the most common cell viability tests is trypan blue dye exclusion where blue-stained cells are counted via brightfield imaging. Typically, live and dead ce
Externí odkaz:
https://doaj.org/article/1d7a1ff11cb7479f845bde61e66d7647
Autor:
Stephanie J, Florczyk, Nathan A, Hotaling, Mylene, Simon, Joe, Chalfoun, Allison L, Horenberg, Nicholas J, Schaub, Dongbo, Wang, Piotr M, Szczypiński, Veronica L, DeFelice, Peter, Bajcsy, Carl G, Simon
Publikováno v:
Journal of Biomedical Materials Research Part A. 111:106-117
The properties and structure of the cellular microenvironment can influence cell behavior. Sites of cell adhesion to the extracellular matrix (ECM) initiate intracellular signaling that directs cell functions such as proliferation, differentiation, a
Autor:
Peter Bajcsy, Soweon Yoon, Stephen J. Florczyk, Nathan A. Hotaling, Mylene Simon, Piotr M. Szczypinski, Nicholas J. Schaub, Carl G. Simon, Mary Brady, Ram D. Sriram
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-23 (2017)
Abstract Background Cell-scaffold contact measurements are derived from pairs of co-registered volumetric fluorescent confocal laser scanning microscopy (CLSM) images (z-stacks) of stained cells and three types of scaffolds (i.e., spun coat, large mi
Externí odkaz:
https://doaj.org/article/ad192240447c4879b02b94b2cf098b2e
Autor:
Greta Babakhanova, Anant Agrawal, Deepika Arora, Allison Horenberg, Jagat B. Budhathoki, Joy P. Dunkers, Joe Chalfoun, Peter Bajcsy, Carl G. Simon
Publikováno v:
Journal of Biomedical Materials Research Part A.
Publikováno v:
Stem Cells Translational Medicine, Vol 5, Iss 6, Pp 705-708 (2016)
The cell therapy industry has identified the inability to reliably characterize cells as possibly its greatest challenge and has called for standards and reference materials to provide assurance for measurements of cell properties. The challenges in
Externí odkaz:
https://doaj.org/article/a5ae2bec2f1f48d685c7fab6c7442797
Publikováno v:
Data in Brief, Vol 5, Iss C, Pp 13-22 (2015)
DiameterJ is an open source image analysis plugin for ImageJ. DiameterJ produces ten files for every image that it analyzes. These files include the images that were analyzed, the data to create histograms of fiber radius, pore size, fiber orientatio
Externí odkaz:
https://doaj.org/article/ded7eabaf54c4bed92a175bf036bf7a5
Autor:
Stephanie J. Florczyk, Nathan A. Hotaling, Mylene Simon, Joe Chalfoun, Allison L. Horenberg, Nicholas J. Schaub, Dongbo Wang, Piotr M. Szczypiński, Veronica L. DeFelice, Peter Bajcsy, Carl G. Simon
Publikováno v:
Journal of Biomedical Materials Research Part A. 111