Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Carl Elkin"'
Autor:
Scott Geraedts, Erica Brand, Thomas R Dean, Sebastian Eastham, Carl Elkin, Zebediah Engberg, Ulrike Hager, Ian Langmore, Kevin McCloskey, Joe Yue-Hei Ng, John C Platt, Tharun Sankar, Aaron Sarna, Marc Shapiro, Nita Goyal
Publikováno v:
Environmental Research Communications, Vol 6, Iss 1, p 015008 (2024)
Persistent contrails make up a large fraction of aviation's contribution to global warming. We describe a scalable, automated detection and matching (ADM) system to determine from satellite data whether a flight has made a persistent contrail. The AD
Externí odkaz:
https://doaj.org/article/f15f3014a15545778fa5b935f0d4a391
Autor:
Kevin McCloskey, Sixing Chen, Vincent R. Meijer, Joe Yue-Hei Ng, Geoff Davis, Carl Elkin, Christopher Van Arsdale, Scott Geraedts
Publikováno v:
Remote Sensing of Environment. 285:113376
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c25e367262b1c19855a7b91371206bca
https://doi.org/10.1016/j.rse.2022.113376
https://doi.org/10.1016/j.rse.2022.113376
Publikováno v:
TARGETS. 1:196-205
In the pharmaceutical industry today, many of the potent compounds discovered using expensive technologies are eventually rejected because of poor physicochemical or absorption, distribution, metabolism, excretion and toxicology (ADME/Tox) properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a1a2f053272bc89cb413c4938e0b471
https://doi.org/10.1016/s1477-3627(02)02274-2
https://doi.org/10.1016/s1477-3627(02)02274-2
Autor:
Carl Elkin, James M. Hogle
Publikováno v:
Journal of Crystal Growth. 232:563-572
Determination of conditions suitable for crystallizing macromolecules often involves many iterative trials. The current standard procedure of manual design of experiments (including manual calculation of volumes of reagents) and recording observation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3975d252140f16554d9d3ed0ba127f47
https://doi.org/10.1016/s0022-0248(01)01085-5
https://doi.org/10.1016/s0022-0248(01)01085-5
Publikováno v:
Journal of Computer-Aided Molecular Design. 14:705-718
Hepatitis delta virus (HDV) encodes a single polypeptide called hepatitis delta antigen (DAg). Dimerization of DAg is required for viral replication. The structure of the dimerization region, residues 12 to 60, consists of an anti-parallel coiled coi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442281f0570a5b882277b3721ebe1b86
https://doi.org/10.1023/a:1008146015629
https://doi.org/10.1023/a:1008146015629
Autor:
John R. Engen, Noriyuki Somerville Kawahata, Thomas E. Wales, D. Allen Annis, Xiangguo Eric Shi, Carl Elkin
Peptide drugs have traditionally suffered from poor pharmacokinetic properties due to their conformational flexibility and the interaction of proteases with backbone amide bonds. “Stapled Peptides” are cyclized using an all-hydrocarbon cross-link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1876ffcfa3c141ee218f5c4eede9135b
https://europepmc.org/articles/PMC3883098/
https://europepmc.org/articles/PMC3883098/
Autor:
Krzysztof Darlak, Hongliang Cai, Eric Feyfant, Tomi K. Sawyer, Packman Kathryn E, Lyubomir T. Vassilev, Christian Tovar, Carl Elkin, Huw M. Nash, James Horstick, D. Allen Annis, Vincent Guerlavais, Anthony M. Manning, Nader Fotouhi, Aditi Mukherjee, Xiangguo E. Shi, Karen A. Olson, Kwong-Him To, Kamala Kesavan, Yong S. Chang, Pamela Berry, Theresa Baker, Zoran Filipovic, Bradford Graves, Farooq Qureshi, Pranoti Gangurde
Publikováno v:
Proceedings of the National Academy of Sciences. 110
Stapled α-helical peptides have emerged as a promising new modality for a wide range of therapeutic targets. Here, we report a potent and selective dual inhibitor of MDM2 and MDMX, ATSP-7041, which effectively activates the p53 pathway in tumors in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bf7583698e4f39a7bb9cea1d284dbf
https://doi.org/10.1073/pnas.1303002110
https://doi.org/10.1073/pnas.1303002110
Publikováno v:
ChemInform. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f5f6302bbf0da411a38a25b6efe628e
https://doi.org/10.1002/chin.200824205
https://doi.org/10.1002/chin.200824205
Publikováno v:
Journal of chemical information and modeling. 48(3)
In the preceding paper (Duca, J. S.; Madison, V. S.; Voigt, J. H. J. Chem. Inf. Model. 2008, 48, 659-668), the accuracy of docking and affinity predictions of the Gold and Glide programs were investigated using single protein conformations spanning 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791570520c1a57e1727fa5f115326146
https://pubmed.ncbi.nlm.nih.gov/18324800
https://pubmed.ncbi.nlm.nih.gov/18324800