Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Carl E. Wagner"'
Autor:
Ankedo Warda, Lech J. P. Staniszewski, Zhela Sabir, Sarah Livingston, Michael Sausedo, Sabeeha Reshi, Eyal Ron, Michael T. Applegate, Dena Haddad, Madleen Khamisi, Pamela A. Marshall, Carl E. Wagner, Peter W. Jurutka
Publikováno v:
Cells, Vol 12, Iss 21, p 2575 (2023)
Bexarotene, a drug approved for treatment of cutaneous T-cell lymphoma (CTCL), is classified as a rexinoid by its ability to act as a retinoid X receptor (RXR) agonist with high specificity. Rexinoids are capable of inducing RXR homodimerization lead
Externí odkaz:
https://doaj.org/article/dc5dc2def7ba449697a87663b640a316
Autor:
Lyndsey A. Reich, Jessica A. Moerland, Ana S. Leal, Di Zhang, Sarah Carapellucci, Beth Lockwood, Peter W. Jurutka, Pamela A. Marshall, Carl E. Wagner, Karen T. Liby
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Rexinoids are ligands which activate retinoid X receptors (RXRs), regulating transcription of genes involved in cancer-relevant processes. Rexinoids have anti-neoplastic activity in multiple preclinical studies. Bexarotene, used to treat cut
Externí odkaz:
https://doaj.org/article/f8d56ac022b34151adecde4d1fbfa621
Autor:
Kavita R. Manhas, Pamela A. Marshall, Carl E. Wagner, Peter W. Jurutka, Michelle V. Mancenido, Hannah Z. Debray, Joseph N. Blattman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Altering T cell trafficking to mucosal regions can enhance immune responses towards pathogenic infections and cancers at these sites, leading to better outcomes. All-trans-retinoic acid (ATRA) promotes T cell migration to mucosal surfaces by inducing
Externí odkaz:
https://doaj.org/article/c0466005fefd484c87693411bca25afd
Autor:
Jennifer Hackney Price, Bentley J. Hanish, Carl E. Wagner, Ichiro Kaneko, Peter W. Jurutka, Pamela A. Marshall
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 1797-1803 (2018)
This article presents the experimental data supporting analysis of differential gene expression of human cutaneous T cell lymphoma (CTCL) cell culture cells (Hut78) treated with bexarotene or a variety of rexinoids, in conjunction with “A Novel Gen
Externí odkaz:
https://doaj.org/article/06619402c8204ce89c52c75cb7fcd983
Autor:
Carl E. Wagner, Thomas L. Groy
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 9, Pp o2340-o2340 (2010)
In the crystal of the title compound, C9H7FO4, classical carboxylate inversion dimers are linked by pairs of O—H...O hydrogen bonds. The packing is consolidated by C—H...F and C—H...O interactions. The benzene ring and the methoxycarbonyl group
Externí odkaz:
https://doaj.org/article/86301fd92fd9490796697bc685d7af2e
Autor:
Karen T. Liby, Carl E. Wagner, Michael B. Sporn, Pamela A. Marshall, Peter W. Jurutka, San Raban, Samir Ibrahim, Jaskaran S. Bhogal, Pritika H. Shahani, Sarah Carapellucci, Ana S. Leal, Di Zhang
Supplemental Figures, Tables and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5315d20ff0355d83035d81d9809a3c
https://doi.org/10.1158/1940-6207.22532393
https://doi.org/10.1158/1940-6207.22532393
Autor:
Peter W. Jurutka, Orsola di Martino, Sabeeha Reshi, Sanchita Mallick, Michael A. Sausedo, Grant A. Moen, Isaac J. Lee, Dominic J. Ivan, Tyler D. Krall, Samuel J. Peoples, Anthony Perez, Lucas Tromba, Anh Le, Iraj Khadka, Ryan Petros, Brianna M. Savage, Eleine Salama, Jakline Salama, Joseph W. Ziller, Youngbin Noh, Ming-Yue Lee, Wei Liu, John S. Welch, Pamela A. Marshall, Carl E. Wagner
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16213
Bexarotene is an FDA-approved drug for the treatment of cutaneous T-cell lymphoma (CTCL); however, its use provokes or disrupts other retinoid-X-receptor (RXR)-dependent nuclear receptor pathways and thereby incites side effects including hypothyroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5d51ef14813e4d35e5fdf19ce65ccc
https://pubmed.ncbi.nlm.nih.gov/36555852
https://pubmed.ncbi.nlm.nih.gov/36555852
Autor:
Aleksandra Grozic, Zhela L. Sabir, Michael C. Heck, Ichiro Kaneko, Marya S. Sabir, Pamela A. Marshall, Sanchita Mallick, Carl E. Wagner, Christoper M. Dussik, Peter W. Jurutka
Publikováno v:
ACS Chemical Neuroscience. 12:857-871
There is considerable interest in identifying effective and safe drugs for neurodegenerative disorders. Cell culture and animal model work have demonstrated that modulating gene expression through RXR-mediated pathways may mitigate or reverse cogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d19d0b4aae7ea3236d25bdcc42e13d
https://doi.org/10.1021/acschemneuro.0c00707
https://doi.org/10.1021/acschemneuro.0c00707
Autor:
Peter W. Jurutka, Orsola di Martino, Sabeeha Reshi, Sanchita Mallick, Michael A. Sausedo, Grant A. Moen, Isaac J. Lee, Dominic J. Ivan, Tyler D. Krall, Samuel J. Peoples, Anthony Perez, Lucas Tromba, Anh Le, Iraj Khadka, Ryan Petros, Brianna M. Savage, Eleine Salama, Jakline Salama, Joseph W. Ziller, Youngbin Noh, Ming-Yue Lee, Wei Liu, John S. Welch, Pamela A. Marshall, Carl E. Wagner
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f11713570e9bcc322808d647a2a27eb4
https://doi.org/10.2139/ssrn.4234530
https://doi.org/10.2139/ssrn.4234530
Autor:
Sarah Carapellucci, Karen T. Liby, Carl E. Wagner, Peter W. Jurutka, Jessica A. Moerland, Pamela A. Marshall, Lyndsey A. Reich, Ana S. Leal, Di Zhang, Beth Lockwood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Scientific Reports
Scientific Reports
Rexinoids are ligands which activate retinoid X receptors (RXRs), regulating transcription of genes involved in cancer-relevant processes. Rexinoids have anti-neoplastic activity in multiple preclinical studies. Bexarotene, used to treat cutaneous T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f13d5dfb3d9cd226c60a7167b651af6
https://doi.org/10.21203/rs.3.rs-826798/v1
https://doi.org/10.21203/rs.3.rs-826798/v1