Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Carl E. Ruby"'
Autor:
Marcus A. Weinman, Stephen A. Ramsey, Haley J. Leeper, Jacqueline V. Brady, Andrew Schlueter, Stanislau Stanisheuski, Claudia S. Maier, Tasha Miller, Carl E. Ruby, Shay Bracha
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Osteosarcoma patients often experience poor outcomes despite chemotherapy treatment, likely due in part to various mechanisms of tumor cell innate and/or acquired drug resistance. Exosomes, microvesicles secreted by cells, have be
Externí odkaz:
https://doaj.org/article/4bd9fc3bf6d244488348fd28d46067e2
Publikováno v:
Veterinary Sciences, Vol 10, Iss 5, p 336 (2023)
The emergence of immunotherapy for the treatment of human cancers has heralded a new era in oncology, one that is making its way into the veterinary clinic. As the immune system of many animal species commonly seen by veterinarians is similar to huma
Externí odkaz:
https://doaj.org/article/777241afbca3494790f2cd4e222efd2a
Autor:
Elise M. Van Fossen, Sonia Grutzius, Carl E. Ruby, Dan V. Mourich, Chris Cebra, Shay Bracha, P. Andrew Karplus, Richard B. Cooley, Ryan A. Mehl
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
A critical step in developing therapeutics for oxidative stress-related pathologies is the ability to determine which specific modified protein species are innocuous by-products of pathology and which are causative agents. To achieve this goal, techn
Externí odkaz:
https://doaj.org/article/e7ee875dac2c4ee68361d8663535c867
Autor:
Jacqueline V. Brady, Ryan M. Troyer, Stephen A. Ramsey, Haley Leeper, Liping Yang, Claudia S. Maier, Cheri P. Goodall, Carl E. Ruby, Hassan A.M. Albarqi, Oleh Taratula, Shay Bracha
Publikováno v:
Translational Oncology, Vol 11, Iss 5, Pp 1137-1146 (2018)
Circulating cancer exosomes are microvesicles which originate from malignant cells and other organs influenced by the disease and can be found in blood. The exosomal proteomic cargo can often be traced to the cells from which they originated, reflect
Externí odkaz:
https://doaj.org/article/c5f26369f77042a39fd77cd703925bd6
Autor:
Andrew D. Weinberg, Alexis Brown, Birat Dhungel, William L. Redmond, Carl E. Ruby, Michael J. Gough
Supplementary Figure 2 from OX40 Agonist Therapy Enhances CD8 Infiltration and Decreases Immune Suppression in the Tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22602b038f88f1f06cae0bfa66a246f3
https://doi.org/10.1158/0008-5472.22374986
https://doi.org/10.1158/0008-5472.22374986
Autor:
Andrew D. Weinberg, Alexis Brown, Birat Dhungel, William L. Redmond, Carl E. Ruby, Michael J. Gough
Acquisition of full T-cell effector function and memory differentiation requires appropriate costimulatory signals, including ligation of the costimulatory molecule OX40 (TNFRSF4, CD134). Tumors often grow despite the presence of tumor-specific T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9068f913fefbbf112166968c819db335
https://doi.org/10.1158/0008-5472.c.6497666
https://doi.org/10.1158/0008-5472.c.6497666
Publikováno v:
Veterinary and Comparative Oncology
Fasting has been shown to decrease chemotherapy‐associated adverse events (AEs), in part through insulin‐like growth factor (IGF‐1) reduction, and may induce a protective effect on normal cells during chemotherapy treatment in mice and people.
Autor:
Carl E. Ruby, Stanislau Stanisheuski, Shay Bracha, Haley Leeper, Tasha Miller, Stephen A. Ramsey, Claudia S. Maier, Jacqueline V. Brady, Andrew Schlueter, Marcus A. Weinman
Publikováno v:
Cancer Cell International
Cancer Cell International, Vol 21, Iss 1, Pp 1-13 (2021)
Cancer Cell International, Vol 21, Iss 1, Pp 1-13 (2021)
Background Osteosarcoma patients often experience poor outcomes despite chemotherapy treatment, likely due in part to various mechanisms of tumor cell innate and/or acquired drug resistance. Exosomes, microvesicles secreted by cells, have been shown
Autor:
Ryan M. Troyer, Carl E. Ruby, Oleh Taratula, Haley Leeper, Cheri P. Goodall, Hassan A. Albarqi, Claudia S. Maier, Jacqueline V. Brady, Stephen A. Ramsey, Shay Bracha, Liping Yang
Publikováno v:
Translational Oncology, Vol 11, Iss 5, Pp 1137-1146 (2018)
Translational Oncology
Translational Oncology
Circulating cancer exosomes are microvesicles which originate from malignant cells and other organs influenced by the disease and can be found in blood. The exosomal proteomic cargo can often be traced to the cells from which they originated, reflect
Autor:
Dan V. Mourich, Jacqueline V. Brady, Oleh Taratula, Liping Yang, Carl E. Ruby, Kallan Bathke, Ryan M. Troyer, Shay Bracha, Claudia S. Maier, Cheri P. Goodall, Hassan A. Albarqi
Publikováno v:
Experimental cell research. 358(2)
Background Canine osteosarcoma (OSA) is the most common cancer of the appendicular skeleton and is associated with high metastatic rate to the lungs and poor prognosis. Recent studies have shown the impact of malignant-derived exosomes on immune cell