Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Carl Co"'
Autor:
Allyson Kwiatkowski, Carl Co, Sei Kameoka, An Zhang, John Coughlin, Tom Cameron, Eric Chiao, Svetlana Bergelson, Cullen Schmid Mason
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
The terminal sugars of Fc glycans can influence the Fc-dependent biological activities of monoclonal antibody therapeutics. Afucosylated N-glycans have been shown to significantly alter binding to FcγRIIIa and affect antibody-dependent cell-mediated
Externí odkaz:
https://doaj.org/article/de7297e0eace436aacfb3a8b6386340a
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 6, p e108 (2007)
Cell polarity is a general cellular process that can be seen in various cell types such as migrating neutrophils and Dictyostelium cells. The Rho small GTP(guanosine 5'-tri phosphate)ases have been shown to regulate cell polarity; however, its mechan
Externí odkaz:
https://doaj.org/article/d38687821a98475dab8fefeb1bf05b16
Autor:
Stephanie A. Houle, Catherine Baillie Abidi, Michelle Birch, Kathryn Reeves, William Younger, Carl Conradi, San Patten, Stéphanie Bélanger, J. Don Richardson, Anthony Nazarov, Samantha Wells
Publikováno v:
European Journal of Psychotraumatology, Vol 15, Iss 1 (2024)
Background: As armed conflict grows increasingly complex, the involvement of children in armed violence across diverse roles is rising. Consequently, military personnel are more likely to encounter children during deployment. However, little is known
Externí odkaz:
https://doaj.org/article/0cfcea31346a440caae2f46c86b08235
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Plaque assays are used to measure the infectious titer of viral samples. These assays are multi-day and low-throughput and may be subject to analyst variability from biased or subjective manual plaque counting. Typically, on day 1, cells are adhered
Publikováno v:
Cell and Gene Therapy Insights. 5:455-463
Autor:
John Coughlin, Allyson Kwiatkowski, Carl Co, Svetlana Bergelson, An Zhang, Cullen Schmid Mason, Eric Chiao, Sei Kameoka, Thomas Cameron
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The terminal sugars of Fc glycans can influence the Fc-dependent biological activities of monoclonal antibody therapeutics. Afucosylated N-glycans have been shown to significantly alter binding to FcγRIIIa and affect antibody-dependent cell-mediated
Autor:
Adriana Bajardi-Taccioli, Tim Brantley, Marina Feschenko, Christine Bond, Allyson Masci, Chongfeng Xu, Svetlana Bergelson, Carl Co
Publikováno v:
Analytical biochemistry. 611
FcγRIIa receptor binding is part of the mechanism of action for many therapeutic antibodies. AlphaScreen® technology and Biolayer Interferometry (BLI) are often used to assess protein-protein interactions. Recently we demonstrated that the presence
Autor:
Heather Jewell, Akinola Olumide Emmanuel, Albert Ruzo, Boris Gorovits, Caspian Harding, Bindu Varghese, Yonatan Lipsitz, Vidur Patel, Justine Cunningham, Sundeep Chandra, Victoria Duback, Hemant Chavan, Joohwan Kim, Michelle Nguyen-McCarty, Shannon Joyce, Aaron E. Foster, Carmela Passaro, Sergey Lyubinetsky, Lauren Pepper, Jason Rodriguez, Trevor McGill, Kelan Hlavaty, Misha Shamashkin, Paige Baldwin, Terry J. Fry, Shirisha Amatya, Carl Co, Salvatore Iovino, Jagesh V Shah, Hanane Ennajdaoui, Jess Elman, Allyse Mazzarelli, Donna Dambach, Kutlu G. Elpek, Carrie Rocca, Vasily Vagin, James Kaczmarek, Pattie Cruite, Michael Laska
Publikováno v:
Blood. 138:2769-2769
Introduction: Ex vivo manufactured chimeric antigen receptor (CAR) T cell therapies are highly effective for treating B cell malignancies. However, the complexity, cost and time required to manufacture CAR T cells limits access. To overcome conventio
Publikováno v:
JMIR Public Health and Surveillance, Vol 10, p e48738 (2024)
BackgroundPopulation size, prevalence, and incidence are essential metrics that influence public health programming and policy. However, stakeholders are frequently tasked with setting performance targets, reporting global indicators, and designing p
Externí odkaz:
https://doaj.org/article/311e7e4af7f9440480efa0cf5825b0c3
Autor:
Christine Roder, Carl Cosgrave, Kathryn Mackie, Bridgette McNamara, Joseph S. Doyle, Amanda J. Wade
Publikováno v:
Viruses, Vol 16, Iss 6, p 979 (2024)
Increasing testing is key to achieving hepatitis C elimination. This retrospective study aimed to assess the testing cascade of patients at a regional hospital in Victoria, Australia, who inject drugs or are living with hepatitis C, to identify misse
Externí odkaz:
https://doaj.org/article/04589bc2fb634603bd8499bb52fe3a16