Výsledky vyhledávání - "Carl C. Smith"

The effect of dietary ascorbic acid and α-tocopherol on fecal mutagenicity

Autor: Peter W. Dion, Carl C. Smith, W.R. Bruce, Elizabeth Bright-See

Publikováno v: Mutation Research/Genetic Toxicology. 102:27-37

The effect of supplemental ascorbic acid and alpha-tocopherol on fecal mutagenicity was examined in 2 studies involving 20 healthy human donors aged 22-55 years. The vitamins were given at a dose of 400 mg daily each. The mutagen was extracted from i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e437cbaeb5064fd1cd28d725730d49e3
https://doi.org/10.1016/0165-1218(82)90143-4

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Correlation of Human Hepatotoxicants with Hepatic Damage in Animals

Autor: A.WALLACE HAYES, TONI FEDOROWSKI, TIBOR BALAZS, WILLIAM W. CARLTON, BRUCE A. FOWLER, MARTIN R. GILMAN, IRWIN HEYMAN, BENJAMIN A. JACKSON, GERALD L. KENNEDY, RAYMOND E. SHAPIRO, CARL C. SMITH, ROBERT G. TARDIFF, CARROL S. WEIL

Publikováno v: Toxicological Sciences. 2:55-66

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::054dd0eeb45c466c320e237f44b0ef4a
https://doi.org/10.1093/toxsci/2.2.55-b

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Influence of cyclophosphamide and 4-ketocyclophosphamide on mouse limb development

Autor: Jeanne M. Manson, Carl C. Smith

Publikováno v: Teratology. 15:291-299

Many studies have been performed on the in vivo teratogenicity of cyclophosphamide, and there is uncertainty whether the parent compound or P-450 generated alkylating metabolite(s) is the proximal teratogen(s). We have examined the influence of cyclo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24beb84220cc410109660484491d4bc9
https://doi.org/10.1002/tera.1420150311

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Effects of cytosine arabinoside on in vivo and in vitro mouse limb development

Autor: Jeanne M. Manson, Carl C. Smith, Michael L. Dourson

Publikováno v: In Vitro. 13:434-442

When pregnant mice were exposed to 40 mg per kg of cytosine arabinoside (ara-C) on days 10 to 12 of gestation, adactylous limbs with large, distally located blisters were found when the fetuses were examined on day 18. Embryonic limbs exposed transpl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ed2f6223e1948026e1fe24601ec6ca
https://doi.org/10.1007/bf02615104

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Antimalarial Activity and Metabolism of Biguanides

Autor: Jean Ihrig, R. Menne, Carl C. Smith

Publikováno v: The American Journal of Tropical Medicine and Hygiene. 10:694-703

Summary The metabolism of chlorguanide (CG) and chlorguanide triazine (CGT) has been investigated following intramuscular and intravenous administration of CG and CGT to monkeys and oral administration of CG to monkeys and man. In confirmation of ear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7be3f0d1c9904246f18f56e48e5efbc2
https://doi.org/10.4269/ajtmh.1961.10.694

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Blood Pressure of the Normal Rhesus Monkey

Autor: Carl C. Smith, Allen Ansevin

Publikováno v: Experimental Biology and Medicine. 96:428-432

SummaryArterial blood pressures have been determined in unanesthetized monkeys by 2 indirect methods. Using a small “newborn” cuff (cloth cuff) on the upper arm and auscultation of the sounds in the brachial artery, mean blood pressure in 14 norm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0278e573657a4594095f8edec116c70
https://doi.org/10.3181/00379727-96-23499

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The Pharmacological Basis for the Prolonged Antimalarial Activity of Pyrimethamine 1

Autor: Jean Ihrig, Carl C. Smith

Publikováno v: The American Journal of Tropical Medicine and Hygiene. 6:50-57

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e9bf27adfc3b97db2d58dbd05746627
https://doi.org/10.4269/ajtmh.1957.6.50

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Experimental Hypertension in the Rhesus Monkey

Autor: Carl C. Smith, Allen Ansevin

Publikováno v: Experimental Biology and Medicine. 96:432-437

SummarySix methods useful in producing experimental hypertension in other laboratory animals were studied in rhesus monkeys. Two methods involving direct constriction of the renal arteries either by silk ligatures or small transparent plastic clamps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68b0f8f8e0a266a562c5bea2bd6a48d
https://doi.org/10.3181/00379727-96-23500

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Lecithin Feeding in the Syndrome of Psoriasis

Autor: Harry H. Fox, Carl C. Smith, Leon Goldman

Publikováno v: Journal of Investigative Dermatology. 5:321-330

In a previous communication one of us (L. G.) (1) has reported the feeding of soybean lecithin mixtures to be of value in some cases of psoriasis. Soybean lecithin was used because of the lipotropic character of the lecithin, and the fact that soybea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e351264c8a2f7463606c8f89191272
https://doi.org/10.1038/jid.1942.47

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A Hemorrhagic Syndrome Induced by Derivatives of 3-Hydroxy-1, 4-Naphthoquinone

Autor: Rochelle Fradkin, Carl C. Smith, Mary D. Lackey

Publikováno v: Experimental Biology and Medicine. 61:398-403

Summary1. A fatal hemorrhagic syndrome accompanied by marked hypoprothrombinemia was produced in rats by the administration of 3 2-substituted-3-hydroxy-1,4-naphthoquinones.2. These compounds produced only minimal pathologic changes in the liver, cau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09697d0268841b2d2b3f3ec27359a2bc
https://doi.org/10.3181/00379727-61-15332

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