Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Carl Bernofsky"'
Publikováno v:
Molecular and Cellular Biochemistry. 148:155-164
Incubation of MC-1010 cells with the spin-trapping agent 5,5-dimethyl-1-pyrroline 1-oxide (DMPO) followed by brief treatment with the solid oxidant lead dioxide (PbO2) yielded, after filtration, a cell-free solution that contained two nitroxyl adduct
Publikováno v:
The Journal of Organic Chemistry. 59:1642-1654
Mixtures of ammonium ion (NH 4 + ) or ammonia (NH 3 ), hypochlorous acid (HOCl), and 5,5-dimethyl-1-pyrroline 1-oxide (DMPO) gave the radical 2-(N-chloroimino)-5,5-dimethylpyrrolidine-1-oxyl (1). The first step in the formation of 1 was the reaction
Publikováno v:
ChemInform. 23
Publikováno v:
The Journal of Organic Chemistry. 57:2652-2657
A novel nitroxyl radical was observed by electron paramagnetic resonance spectroscopy (EPR) of reaction mixtures containing ammonium ion, hypochlorous acid (HOCl), and 5,5-dimethyl-1-pyrroline 1-oxide (DMPO). The structure of this radical was establi
Autor:
Carl Bernofsky
Publikováno v:
The FASEB Journal. 5:295-300
Hypochlorite is a reactive oxidant formed as an end product of the respiratory burst in activated neutrophils. It is responsible for killing bacteria and has been implicated in neutrophil-mediated tissue injury associated with the inflammatory proces
Publikováno v:
Nucleosides and Nucleotides. 9:189-195
2′-O-Tosyladenosine (1) was obtained in 50% yield from the reaction of adenosine and sodium p-toluenesulfinate in the presence of sodium hypochlorite. The sequential intermediacy of N6−monochloroadenosine (2) and p-toluenesulfonyl chloride during
Publikováno v:
Free Radical Research Communications. 9:303-315
Adenosine and its nucleotides react with hypochlorite to form unstable products that have been identified as the N6 chloramine derivatives. These chloramines spontaneously oligomerize, form stable adducts with proteins and nucleic acids, and are conv
Publikováno v:
Free radical biologymedicine. 8(3)
The reaction of hypochlorous acid with the spin trap, 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) was found to yield 5,5-dimethyl-2-pyrrolidone-N-oxyl (DMPOX). In addition to DMPOX, 5,5-dimethyl-2-hydroxypyrrolidine-N-oxyl (DMPO-OH) and an unidentified c
Autor:
William J. Gallagher, Carl Bernofsky
Publikováno v:
Analytical Biochemistry. 67:611-624
A single-column technique is described for separating the naturally occurring nicotinic acid- and nicotinamide-containing nucleosides and nucleotides. A unique feature of the system is the use of conductivity measurements as a reproducible means of p
Autor:
Carl Bernofsky, William J. Gallagher
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Enzymology. 659:1-6
Mixtures of NADH and NADP+ or NADPH and NAD+ were incubated and periodically assayed for hydrogen transfer by measuring the formation of NADPH and NADH with glutathione reductase (NAD(P)H: oxidized-glutathione oxidoreductase, EC 1.6.4.2) and lactate