Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Carl B. Watt"'
Autor:
Bryan William Jones, Rebecca Lynne Pfeiffer, William Drew Ferrell, Carl B Watt, James eTucker, Robert E Marc
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
Age-related macular degeneration (AMD) is a progressive retinal degeneration resulting in central visual field loss, ultimately causing debilitating blindness. AMD affects 18% of Americans from 65 to 74, 30% older than 74 years of age and is the lead
Externí odkaz:
https://doaj.org/article/b104b5731266484791c2de0097665d11
Autor:
Kevin Rapp, Alexis R. Houser, James R. Anderson, Crystal Sigulinsky, Hope Morrison, Jessica C. Garcia, Carl B. Watt, Jia-Hui Yang, Daniel Emrich, Rebecca L. Pfeiffer, Jeebika Dahal, Robert E. Marc, Bryan W. Jones
Connectomics has demonstrated that synaptic networks and their topologies are precise and directly correlate with physiology and behavior. The next extension of connectomics is pathoconnectomics: to map neural network synaptology and circuit topologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4062bac463abd557b20395ca1ae03430
Autor:
James R Anderson, Bryan W Jones, Jia-Hui Yang, Marguerite V Shaw, Carl B Watt, Pavel Koshevoy, Joel Spaltenstein, Elizabeth Jurrus, Kannan U V, Ross T Whitaker, David Mastronarde, Tolga Tasdizen, Robert E Marc
Publikováno v:
PLoS Biology, Vol 7, Iss 3, p e1000074 (2009)
Circuitry mapping of metazoan neural systems is difficult because canonical neural regions (regions containing one or more copies of all components) are large, regional borders are uncertain, neuronal diversity is high, and potential network topologi
Externí odkaz:
https://doaj.org/article/110bcb5e76134dd490902ad6459178b1
Autor:
Daniel Emrich, Jessica C. Garcia, Jia-Hui Yang, Hope Morrison, Robert E. Marc, Mineo Kondo, James R. Anderson, Crystal Sigulinsky, Carl B. Watt, Hiroko Terasaki, Jeebika Dahal, Bryan W. Jones, Kevin Rapp, Rebecca L. Pfeiffer
Publikováno v:
Retinal Degenerative Diseases ISBN: 9783030273774
Glia play important roles in neural function, including but not limited to amino acid recycling, ion homeostasis, glucose metabolism, and waste removal. During retinal degeneration and subsequent retinal remodeling, Müller cells (MCs) are the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127a6046d2d4bcfe231f554219e44abf
https://doi.org/10.1007/978-3-030-27378-1_60
https://doi.org/10.1007/978-3-030-27378-1_60
Autor:
Carl B. Watt, Michael F. Marmor, William D. Ferrell, Bryan W. Jones, Rebecca L. Pfeiffer, Robert E. Marc
Publikováno v:
Experimental Eye Research. 150:149-165
Retinitis Pigmentosa (RP) in the human is a progressive, currently irreversible neural degenerative disease usually caused by gene defects that disrupt the function or architecture of the photoreceptors. While RP can initially be a disease of photore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e09a56406d4cb52631960841253c6d5
Autor:
Jessica C. Garcia, Robert E. Marc, Crystal Sigulinsky, Daniel Emrich, Bryan W. Jones, Jeebika Dahal, Kevin Rapp, Rebecca L. Pfeiffer, Alexis R. Houser, James R. Anderson, Carl B. Watt, Jia-Hui Yang, Hope Ab Johnstun
Publikováno v:
Exp Eye Res
Connectomics has demonstrated that synaptic networks and their topologies are precise and directly correlate with physiology and behavior. The next extension of connectomics is pathoconnectomics: to map neural network synaptology and circuit topologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec61c1e8e89984c8b7f529c8821ac143
https://doi.org/10.1016/j.exer.2020.108196
https://doi.org/10.1016/j.exer.2020.108196
Autor:
Edward N. Pugh, Emily Dennis, Tao Zhang, Alex Jones, Carl B. Watt, Yingbin Fu, S. Wang, Nduka Enemchukwu
Publikováno v:
Human Molecular Genetics. 24:1755-1763
Mutations in RPE65 or lecithin-retinol acyltransferase (LRAT) disrupt 11-cis-retinal synthesis and cause Leber congenital amaurosis (LCA), a severe hereditary blindness occurring in early childhood. The pathology is attributed to a combination of 11-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0cb09276d364dc4f415a4151b6164e
https://doi.org/10.1093/hmg/ddu588
https://doi.org/10.1093/hmg/ddu588
Autor:
Crystal Sigulinsky, Carl B. Watt, Robert E. Marc, James R. Anderson, Scott Lauritzen, Bryan W. Jones
Publikováno v:
Progress in Retinal and Eye Research. 37:141-162
Connectomics is a strategy for mapping complex neural networks based on high-speed automated electron optical imaging, computational assembly of neural data volumes, web-based navigational tools to explore 10 12 –10 15 byte (terabyte to petabyte) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3daf33cc89d70a02d129e27b61d208fc
https://doi.org/10.1016/j.preteyeres.2013.08.002
https://doi.org/10.1016/j.preteyeres.2013.08.002
Autor:
John Hoang, Carl B. Watt, James R. Anderson, J. Scott Lauritzen, Shoeb Mohammed, Bryan W. Jones, Robert E. Marc
Publikováno v:
Journal of Comparative Neurology. 521:977-1000
Analysis of the rabbit retinal connectome RC1 reveals that the division between the ON and the OFF inner plexiform layer (IPL) is not structurally absolute. ON cone bipolar cells make noncanonical axonal synapses onto specific targets and receive ama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ab63e928fbe2f85163f96890b0c555
https://doi.org/10.1002/cne.23244
https://doi.org/10.1002/cne.23244
Autor:
Robert E. Marc, Carl B. Watt, James Tucker, William D. Ferrell, Bryan W. Jones, Rebecca L Pfeiffer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Age-related macular degeneration (AMD) is a progressive retinal degeneration resulting in central visual field loss, ultimately causing debilitating blindness. AMD affects 18% of Americans from 65 to 74, 30% older than 74 years of age and is the lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8c6a71ae29648bc9e76a19dc6d3161