Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Carl B Goodman"'
Autor:
Ramesh B Badisa, Sanjay S Kumar, Elizabeth Mazzio, Rasheda D Haughbrook, John R Allen, Michael W Davidson, Cheryl A Fitch-Pye, Carl B Goodman
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0114285 (2015)
Cocaine has a short half-life of only about an hour but its effects, predominantly on the central nervous system (CNS), are fairly long-lasting. Of all cells within the CNS, astrocytes may be the first to display cocaine toxicity owing to their relat
Externí odkaz:
https://doaj.org/article/1779d78db14c406dbb7059a0ebbdbd85
Autor:
Selina Darling-Reed, Karam F.A. Soliman, Kesa Randell, Lekan M. Latinwo, Chantel Wiley, Ramesh B. Badisa, Carl B. Goodman, Maryam Agharahimi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Methamphetamine (METH) is a powerfully addictive psychostimulant that has a pronounced effect on the central nervous system (CNS). The present study aimed to assess METH toxicity in differentiated C6 astroglia-like cells through biochemical and toxic
Publikováno v:
Biomedical Reports
Cocaine is a highly addictive drug that mediates its effect through altering dopamine metabolism in the central nervous system (CNS), resulting in a feeling of euphoria. Owing to its high lipophilicity, cocaine easily crosses the blood brain barrier
Autor:
Jens T. Rosenberg, Ramesh B. Badisa, Carl B. Goodman, Elizabeth Mazzio, Sungsool Wi, Samuel C. Grant, Lekan M. Latinwo, Yi Zhou, Zachary Jones
Publikováno v:
Cell Death Discovery, Vol 4, Iss 1, Pp 1-14 (2018)
Cell Death Discovery
Cell Death Discovery
Cocaine is a highly abused drug that causes psychiatric and neurological problems. Its entry into neurons could alter cell-biochemistry and contribute in the manifestation of early pathological symptoms. We have previously shown the acute cocaine eff
Autor:
Elizabeth Mazzio, Carl B. Goodman, Ramesh B. Badisa, Riccardo Jean, Kinfe K. Redda, Karam F.A. Soliman, Madhavi Gangapuram, Suresh Eyunni
Publikováno v:
Anticancer Research. 36:5043-5052
Triple-negative breast cancer (TNBC) occurs in greater frequency amongst African-Americans, and is characterized by the absence of estrogen receptor (ER), progesterone receptor (PR) and human epidermal receptor 2 (HER2). TNBC is often invasive and ty
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Cocaine is one of the powerful addictive drugs, widely abused in most Western countries. Because of high lipophilic nature, cocaine easily reaches various domains of the central nervous system (CNS) and triggers different levels of cellular toxicity.
Autor:
Karam F.A. Soliman, Equar Taka, Elizabeth Mazzio, R. Renee Reams, Natalie Redmon, Carl B. Goodman, Hernan Flores-Rozas, Selina Darling-Reed
Publikováno v:
Journal of Neuroimmunology. 286:5-12
Thymoquinone (TQ), the main pharmacological active ingredient within the black cumin seed (Nigella sativa) is believed to be responsible for therapeutic effects on chronic inflammatory conditions such as arthritis, asthma and neurodegeneration. In th
Autor:
Ramesh B. Badisa, Maryam Agharahimi, Cheryl A. Fitch-Pye, Carl B. Goodman, Donald E. Palm, Lekan M. Latinwo
Publikováno v:
Molecular Medicine Reports
Cocaine is a powerful addictive drug, widely abused in most Western countries. It easily reaches various domains within and outside of the central nervous system (CNS), and triggers varying levels of cellular toxicity. No pharmacological treatment is
Publikováno v:
International Journal of Molecular Medicine
Astroglial cells are one of the most abundant cell types in the mammalian brain functioning in neuronal survival and in maintenance of fundamental patterns of circuitry. To date, no study has been conducted regarding the short-term impact of cocaine
Publikováno v:
International Journal of Molecular Medicine
Morphine is an effective analgesic that acts by binding to the μ-opioid receptor (MOR) coded in the human by the OPRM1 gene. In the present study, we investigated the regulation of μ-opioid receptor (MOR-1) mRNA levels in all-trans-retinoic acid-di