Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Carl Arneson"'
Autor:
Victor F. Tapson, Zhi-Cheng Jing, Kai-Feng Xu, Lei Pan, Jeremy Feldman, David G. Kiely, Eugene Kotlyar, C. Shane McSwain, Kevin Laliberte, Carl Arneson, Lewis J. Rubin
Publikováno v:
Chest. 144:952-958
Autor:
Shelley M. Shapiro, Victor F. Tapson, Kevin Laliberte, Roblee P Allen, Robert P. Frantz, Anne Keogh, Carl Arneson, Fernando Torres, Jeffrey Sigman, David B. Badesch, Adaani E. Frost, Fiona Kermeen, Nazzareno Galiè
Publikováno v:
Chest. 142:1383-1390
Background Treprostinil is a stable prostacyclin analog approved for the treatment of pulmonary arterial hypertension (PAH) as parenteral or inhaled therapy. Treprostinil diolamine, a sustained-release oral formulation of treprostinil, was studied to
Publikováno v:
The Journal of Heart and Lung Transplantation. 30:982-989
Because of the challenges associated with conducting large survival studies of patients with pulmonary arterial hypertension (PAH), we analyzed the surrogate markers predictive of long-term survival in a large cohort of patients treated with subcutan
Autor:
Carl Arneson, Somasundaram Shanmugasundaram, Leland Shapiro, Jagdish Hiremath, Cindy L. Vnencak-Jones, Gregory B. Pott, R. James White, Sudhakar Bangera, Keyur Parikh, Sadagopa Thanikachalam, Michael Wade
Publikováno v:
The Journal of Heart and Lung Transplantation. 29:137-149
Background Pulmonary arterial hypertension (PAH) remains a poorly understood and frequently lethal disease with few treatment options. Methods We conducted a placebo-controlled trial of intravenous treprostinil, a prostacyclin analog, in treatment-na
Autor:
Dianne L. Zwicke, Vallerie V. McLaughlin, C. Gregory Elliott, Carl Arneson, Ronald J. Oudiz, Shelley M. Shapiro, C. Shane McSwain, Robert Schilz, Michael Wade, Ray Benza, Nicholas S. Hill, James P. Staszewski, David Zaccardelli
Publikováno v:
The Journal of Clinical Pharmacology. 48:19-25
19 This study assessed the relationship between dose and plasma concentration following administration of treprostinil sodium infusion therapy in pulmonary arterial hypertension patients. This was a multicenter, open-label, multiple-cohort, steady-st
Autor:
Allen A. Lai, Thomas L. Hunt, F. Jo Baker, Michael Wade, Carl Arneson, Wayne DellaMaestra, Robert Roscigno
Publikováno v:
The Journal of Clinical Pharmacology. 44:503-509
The objective of this study was to assess the pharmacokinetics and safety of treprostinil sodium administered as a 28-day continuous subcutaneous infusion at escalating infusion rates of 2.5 to 15 ng/kg/min in normal subjects. Fourteen healthy adult
There are limited data on the management of pulmonary arterial hypertension (PAH) in the elderly; therefore, this analysis compared the safety and efficacy of tadalafil between patients ≥65 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d70675631df4a99ce686d954febe38f
https://europepmc.org/articles/PMC4070753/
https://europepmc.org/articles/PMC4070753/
Autor:
Carlos Jerjes-Sánchez, Kevin Laliberte, Tomás Pulido, Keyur Parikh, Lewis J. Rubin, Zhi-Cheng Jing, Adam Torbicki, Carl Arneson, R. James White, Roblee P Allen, Kai Feng Xu, David Yehle
Publikováno v:
Circulation. 127(5)
Background— Pulmonary arterial hypertension (PAH) is a progressive, fatal disease with no cure. Parenteral and inhaled prostacyclin analogue therapies are effective for the treatment of PAH, but complicated administration requirements can limit the
Autor:
Erika B. Rosenzweig, S. Karl Gotzkowsky, Hubert Chen, Carl Arneson, Robert C. Bourge, Andrew Nelsen
Publikováno v:
Health and Quality of Life Outcomes
Background Patient treatment satisfaction is likely to be a highly relevant outcome measure in pulmonary arterial hypertension (PAH), a condition for which the benefits of treatment must be weighed against frequent, undesirable side effects, inconven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e7fe6cfa550ee73500ace33511664b
Autor:
Victor F, Tapson, Fernando, Torres, Fiona, Kermeen, Anne M, Keogh, Roblee P, Allen, Robert P, Frantz, David B, Badesch, Adaani E, Frost, Shelley M, Shapiro, Kevin, Laliberte, Jeffrey, Sigman, Carl, Arneson, Nazzareno, Galiè
Publikováno v:
Chest. 142(6)
Infused and inhaled treprostinil are effective for treatment of pulmonary arterial hypertension (PAH), although their administration routes have limitations. This study assessed the efficacy and safety of bid oral sustained-release treprostinil in th