Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Carl A Hubel"'
Autor:
Robin E Gandley, Andrew Althouse, Arundhathi Jeyabalan, Julia M Bregand-White, Stacy McGonigal, Ashley C Myerski, Marcia Gallaher, Robert W Powers, Carl A Hubel
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157608 (2016)
INTRODUCTION:Syndecan-1 (Sdc1; CD138) is a major transmembrane heparan sulfate proteoglycan expressed on the extracellular, luminal surface of epithelial cells and syncytiotrophoblast, thus comprising a major component of the glycocalyx of these cell
Externí odkaz:
https://doaj.org/article/255e48502dad40ac9355219583b5592d
Autor:
Lars Brodowski, Jennifer Burlakov, Ashley C Myerski, Constantin S von Kaisenberg, Magdalena Grundmann, Carl A Hubel, Frauke von Versen-Höynck
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98527 (2014)
Placenta-derived circulating factors contribute to the maternal endothelial dysfunction underlying preeclampsia. Endothelial colony forming cells (ECFC), a sub-population of endothelial progenitor cells (EPCs), are thought to be involved in vasculoge
Externí odkaz:
https://doaj.org/article/b4a543908e15424da543045d3c77dcbb
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98990 (2014)
Endothelial dysfunction is a primary feature of preeclampsia, a pregnancy complication associated with an increased future cardiovascular risk for mother and offspring. Endothelial colony forming cells (ECFC) are endothelial progenitor cells that par
Externí odkaz:
https://doaj.org/article/f4b57706e12a48acbe59e10aeec8fd83
Autor:
Shuwei Liu, Haoyi Fu, Mitali Ray, Lacey W. Heinsberg, Yvette P. Conley, Cindy M. Anderson, Carl A. Hubel, James M. Roberts, Arun Jeyabalan, Daniel E. Weeks, Mandy J. Schmella
Publikováno v:
Epigenetics Communications, Vol 3, Iss 1, Pp 1-16 (2023)
Abstract Background While preeclampsia (PE) is a leading cause of pregnancy-related morbidity/mortality, its underlying mechanisms are not fully understood. DNA methylation (DNAm) is a dynamic regulator of gene expression that may offer insight into
Externí odkaz:
https://doaj.org/article/c5c35e1db21045b7bdeac7182c030bde
Autor:
Mitali Ray, Lacey W. Heinsberg, Yvette P. Conley, James M. Roberts, Arun Jeyabalan, Carl A. Hubel, Daniel E. Weeks, Mandy J. Schmella
Publikováno v:
Hypertension in Pregnancy, Vol 40, Iss 4, Pp 312-321 (2021)
Objective: Examine white blood cell (WBC) proportions across preeclamptic (n = 28 cases) and normotensive (n = 28 controls) pregnancy in individuals with overweight/obesity. Methods: WBC proportions were inferred from genome-wide DNA methylation data
Externí odkaz:
https://doaj.org/article/447addb74d7e4940a3e0636e48815149
Autor:
Marie‐Pierre St‐Onge, Brooke Aggarwal, Matthew A. Allison, Jeffrey S. Berger, Sheila F. Castañeda, Janet Catov, Judith S. Hochman, Carl A. Hubel, Sanja Jelic, David A. Kass, Nour Makarem, Erin D. Michos, Lori Mosca, Pamela Ouyang, Chorong Park, Wendy S. Post, Robert W. Powers, Harmony R. Reynolds, Dorothy D. Sears, Sanjiv J. Shah, Kavita Sharma, Tanya Spruill, Gregory A. Talavera, Dhananjay Vaidya
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)
Abstract The Go Red for Women movement was initiated by the American Heart Association (AHA) in the early 2000s to raise awareness concerning cardiovascular disease (CVD) risk in women. In 2016, the AHA funded 5 research centers across the United Sta
Externí odkaz:
https://doaj.org/article/c6e5c9e6dfe445038398588030d2f790
Autor:
Baiyang Sun, Marnie Bertolet, Maria M. Brooks, Carl A. Hubel, Cora E. Lewis, Erica P. Gunderson, Janet M. Catov
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 15 (2020)
Background Women who deliver preterm infants (
Externí odkaz:
https://doaj.org/article/c28227f2d54e46fda59cc92500a4bdb9
Autor:
Lars Brodowski, Tristan Zindler, Sandra von Hardenberg, Bianca Schröder-Heurich, Constantin S. von Kaisenberg, Helge Frieling, Carl A. Hubel, Thilo Dörk, Frauke von Versen-Höynck
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
ObjectiveThe pregnancy complication preeclampsia represents an independent risk factor for cardiovascular disease. Our previous research shows a diminished function of fetal endothelial colony-forming cells (ECFC), a proliferative subgroup of endothe
Externí odkaz:
https://doaj.org/article/263ac4dc1e2f4da882f687b9f690cf0e
Autor:
Janet M. Catov, Matthew F. Muldoon, Robin E. Gandley, Judith Brands, Alisse Hauspurg, Carl A. Hubel, Marie Tuft, Mandy Schmella, Gong Tang, W. Tony Parks
Publikováno v:
Hypertension
Women with adverse pregnancy outcomes later experience excess hypertension and cardiovascular disease, but how the events are linked is unknown. Examination of the placenta may provide clues to vascular impairments after delivery. Maternal vascular m
Autor:
James M. Roberts, Carl A. Hubel, Yvette P. Conley, Lacey W. Heinsberg, Daniel E. Weeks, Arun Jeyabalan, Mandy J. Schmella, Mitali Ray
Publikováno v:
Reprod Sci
Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality. Chronological age and race are associated with preeclampsia, but the role of these factors is not entirely understood. We hypothesized that DNA methylation age, a measu