Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Carl‐Fredrik Tiger"'
Autor:
Carl‐Fredrik Tiger, Falko Krause, Gunnar Cedersund, Robert Palmér, Edda Klipp, Stefan Hohmann, Hiroaki Kitano, Marcus Krantz
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-20 (2012)
Abstract Intracellular signalling systems are highly complex. This complexity makes handling, analysis and visualisation of available knowledge a major challenge in current signalling research. Here, we present a novel framework for mapping signal‐
Externí odkaz:
https://doaj.org/article/7469b0e7c62d4355ba289a0e218b9f33
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e14791 (2011)
In systems biology uncertainty about biological processes translates into alternative mathematical model candidates. Here, the goal is to generate, fit and discriminate several candidate models that represent different hypotheses for feedback mechani
Externí odkaz:
https://doaj.org/article/d2fc6688172449b78dcb94758fde5722
Autor:
Stefan Hohmann, Carl Fredrik Tiger, Joerg Schaber, Roja Babazadeh, Niek Welkenhuysen, Edda Klipp, Soheil Rastgou Talemi, Mikael Andersson
Publikováno v:
Scientific Reports
Adaptation is an important property of living organisms enabling them to cope with environmental stress and maintaining homeostasis. Adaptation is mediated by signaling pathways responding to different stimuli. Those signaling pathways might communic
Autor:
Henrik Hagberg, Changlian Zhu, Carl Fredrik Tiger, Åsa Rosen, Kristina Eriksson, Xiaoyang Wang, Carina Mallard, Maj Hedtjärn, Bo Jacobsson
Publikováno v:
The American Journal of Pathology. 169:967-976
Preterm birth is a major contributor of adverse perinatal outcome. Clinical data suggest that an inflammatory response is important in the process leading to preterm labor. By using a recently introduced mouse model of localized intrauterine lipopoly
Autor:
Fredrik Johansson, Josefin Brodd, Bengt Westermark, Charlotta Eklöf, Maria Ferletta, Lene Uhrbom, Göran Hesselager, Carl-Fredrik Tiger
Publikováno v:
Proceedings of the National Academy of Sciences. 101:11334-11337
Murine retroviruses may cause malignant tumors in mice by insertional mutagenesis of host genes. The use of retroviral tagging as a means of identifying cancer-causing genes has, however, almost entirely been restricted to hematopoietic tumors. The a
Publikováno v:
Experimental Cell Research. 248:627-633
Changes in basement membrane structure are known to accompany carcinoma formation. We analyzed laminin alpha1 and alpha5 chains in colon carcinoma cell lines. Variable levels of the Mr 380,000 alpha5 laminin protein and 11-kb alpha5 laminin mRNA were
Autor:
Carl-Fredrik Tiger, Donald Gullberg
Publikováno v:
Muscle & Nerve. 20:1515-1524
In Duchenne muscular dystrophy (DMD) and laminin alpha2 defective congenital muscular dystrophies (CMD) there are reports of an induction of laminin alpha1 chain in regenerating muscle fibers. These studies are based on immunohistochemistry data with
Autor:
Marie-France Champliaud, Fatima Pedrosa-Domellöf, Lars-Eric Thornell, Carl-Fredrik Tiger, Peter Ekblom, Donald Gullberg
Publikováno v:
Journal of Biological Chemistry. 272:28590-28595
There is currently a great interest in identifying laminin isoforms expressed in developing and regenerating skeletal muscle. Laminin alpha1 has been reported to localize to human fetal muscle and to be induced in muscular dystrophies based on immuno
Autor:
Gunnar Sjöberg, Carl-Fredrik Tiger, Katriina Salmivirta, Donald Gullberg, Teet Velling, Lars Edström, Thomas Sejersen, Barbara Gaggero
Publikováno v:
Karolinska Institutet
Tenascin-C (TN-C) is an extracellular matrix protein expressed during development in several tissues, but restricted to only a few areas in normal adult tissues. By immunizing mice with human fetal myoblasts we generated a monoclonal antibody to TN-C
Autor:
Stefan Hohmann, Edda Klipp, Marcus Krantz, Robert Palmér, Carl Fredrik Tiger, Falko Krause, Hiroaki Kitano, Gunnar Cedersund
Publikováno v:
Molecular Systems Biology
Molecular Systems Biology; Vol 8
Molecular Systems Biology; Vol 8
An intuitive formalism for reconstructing cellular networks from empirical data is presented, and used to build a comprehensive yeast MAP kinase network. The accompanying rxncon software tool can convert networks to a range of standard graphical form