Emergence of the B.1.214.2 SARS-CoV-2 lineage with an Omicron-like spike insertion and a unique upper airway immune signature

Autor: Andrew Holtz, Johan Van Weyenbergh, Samuel L. Hong, Lize Cuypers, Áine O’Toole, Gytis Dudas, Marco Gerdol, Barney I. Potter, Francine Ntoumi, Claujens Chastel Mfoutou Mapanguy, Bert Vanmechelen, Tony Wawina-Bokalanga, Bram Van Holm, Soraya Maria Menezes, Katja Soubotko, Gijs Van Pottelbergh, Elke Wollants, Pieter Vermeersch, Ann-Sophie Jacob, Brigitte Maes, Dagmar Obbels, Veerle Matheeussen, Geert Martens, Jérémie Gras, Bruno Verhasselt, Wim Laffut, Carl Vael, Truus Goegebuer, Rob van der Kant, Frederic Rousseau, Joost Schymkowitz, Luis Serrano, Javier Delgado, Tom Wenseleers, Vincent Bours, Emmanuel André, Marc A. Suchard, Andrew Rambaut, Simon Dellicour, Piet Maes, Keith Durkin, Guy Baele

Publikováno v: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-18 (2024)

Abstract We investigate the emergence, mutation profile, and dissemination of SARS-CoV-2 lineage B.1.214.2, first identified in Belgium in January 2021. This variant, featuring a 3-amino acid insertion in the spike protein similar to the Omicron vari

Externí odkaz: https://doaj.org/article/e0f6914f63ac463b94c41b5682afba1e

Nationwide Harmonization Effort for Semi-Quantitative Reporting of SARS-CoV-2 PCR Test Results in Belgium

Autor: Lize Cuypers, Jannes Bode, Kurt Beuselinck, Lies Laenen, Klaas Dewaele, Reile Janssen, Arnaud Capron, Yves Lafort, Henry Paridaens, Bertrand Bearzatto, Mathieu Cauchie, Aline Huwart, Jonathan Degosserie, Olivier Fagnart, Yarah Overmeire, Arlette Rouffiange, Ilse Vandecandelaere, Marine Deffontaine, Thomas Pilate, Nicolas Yin, Isabel Micalessi, Sandrine Roisin, Veronique Moons, Marijke Reynders, Sophia Steyaert, Coralie Henin, Elena Lazarova, Dagmar Obbels, François E. Dufrasne, Hendri Pirenne, Raf Schepers, Anaëlle Collin, Bruno Verhasselt, Laurent Gillet, Stijn Jonckheere, Philippe Van Lint, Bea Van den Poel, Yolien Van der Beken, Violeta Stojkovic, Maria-Grazia Garrino, Hannah Segers, Kevin Vos, Maaike Godefroid, Valerie Pede, Friedel Nollet, Vincent Claes, Inge Verschraegen, Pierre Bogaerts, Marjan Van Gysel, Judith Leurs, Veroniek Saegeman, Oriane Soetens, Merijn Vanhee, Gilberte Schiettekatte, Evelyne Huyghe, Steven Martens, Ann Lemmens, Heleen Nailis, Kim Laffineur, Deborah Steensels, Elke Vanlaere, Jérémie Gras, Gatien Roussel, Koenraad Gijbels, Michael Boudewijns, Catherine Sion, Wim Achtergael, Wim Maurissen, Luc Iliano, Marianne Chantrenne, Geert Vanheule, Reinoud Flies, Nicolas Hougardy, Mario Berth, Vanessa Verbeke, Robin Morent, Anne Vankeerberghen, Sébastien Bontems, Kaat Kehoe, Anneleen Schallier, Giang Ho, Kristof Bafort, Marijke Raymaekers, Yolande Pypen, Amelie Heinrichs, Wim Schuermans, Dominique Cuigniez, Salah Eddine Lali, Stefanie Drieghe, Dieter Ory, Marie Le Mercier, Kristel Van Laethem, Inge Thoelen, Sarah Vandamme, Iqbal Mansoor, Carl Vael, Maxime De Sloovere, Katrien Declerck, Elisabeth Dequeker, Stefanie Desmet, Piet Maes, Katrien Lagrou, Emmanuel André

Publikováno v: Viruses, Vol 14, Iss 6, p 1294 (2022)

From early 2020, a high demand for SARS-CoV-2 tests was driven by several testing indications, including asymptomatic cases, resulting in the massive roll-out of PCR assays to combat the pandemic. Considering the dynamic of viral shedding during the

Externí odkaz: https://doaj.org/article/9e84aba5685e427f95431c13c8f8b137

Proof of principle study replicating microbial clusters in connection to birth mode and diet in the early life intestine

Autor: Patrick Schimmel, Lennart Kleinjans, Carl Vael, Kristine Desager, Jan Knol, Clara Belzer

Publikováno v: PLoS ONE 17 (2022) 11
PLoS ONE, 17(11)

The human gut ecosystem starts developing at birth and is influenced by many factors during early life. In this study we make use of a Belgian cohort of 64 children, followed until the age of 6 years, to analyze different phases of microbiota develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5e98d2d574170db3c2cdf55d4132fc
https://research.wur.nl/en/publications/proof-of-principle-study-replicating-microbial-clusters-in-connec

Intrauterine Exposure to Environmental Pollutants and Body Mass Index during the First 3 Years of Life

Autor: Caroline Beunckens, Vera Nelen, Greet Schoeters, Carl Vael, Gudrun Koppen, Stijn Verhulst, Kristine Desager, Elly Den Hond

Publikováno v: Environmental Health Perspectives
Environmental health perspectives

Objective: We investigated the association between body mass index (BMI) standard deviation score (SDS) and prenatal exposure to hexachlorobenzene, dichlorodiphenyldichloroethylene (DDE) , dioxin-like compounds, and polychlorinated biphenyls (PCBs) .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25deff609288687aaa08f800386e1134
https://doi.org/10.1289/ehp.0800003

Differences in gut microbiota composition between obese and lean children : a cross-sectional study

Autor: Carl Vael, Kim Van Hoorenbeeck, Niel Hens, Liene Bervoets, Herman Goossens, Vanessa Vankerckhoven, Kristine Desager, Ineke Kortleven, Caroline Van Noten

Publikováno v: Gut pathogens
Gut Pathogens

Background: An altered gut microbiota composition has recently been linked to obesity. The principal aim of this study is to investigate and compare the gut microbiota composition in obese and lean children. Secondly, associations between analysed gu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b41aa5bc04bf2776a87fc192039d8e0
https://hdl.handle.net/10067/1078450151162165141