Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Carl, Petersson"'
Autor:
Christian Sommerauer, Carlos J Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinc Sezgin, Marion Korach-André, Carl Petersson, Hannes Hagström, Volker M Lauschke, Amena Archer, Cecilia Williams, Claudia Kutter
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 374-402 (2024)
Abstract Sex-based differences in obesity-related hepatic malignancies suggest the protective roles of estrogen. Using a preclinical model, we dissected estrogen receptor (ER) isoform-driven molecular responses in high-fat diet (HFD)-induced liver di
Externí odkaz:
https://doaj.org/article/ee239cfd60044f218b6abfe27eac0000
Autor:
Andreas Blum, Dieter Dorsch, Nina Linde, Susanne Brandstetter, Hans-Peter Buchstaller, Michael Busch, Nina Glaser, Ulrich Grädler, Aaron Ruff, Carl Petersson, Hanno Schieferstein, Eva Sherbetjian, Christina Esdar
Publikováno v:
Journal of Medicinal Chemistry. 66:2386-2395
Autor:
Johan Winges, Thomas Rylander, Carl Petersson, Christian Ekman, Lars-Åke Johansson, Tomas McKelvey
Publikováno v:
Transactions on Environment and Electrical Engineering, Vol 2, Iss 2, Pp 86-92 (2018)
We present a procedure for system identification and tuning of a wireless power transfer (WPT) system with four magnetically coupled resonators, where each resonator consists of a coil and a capacitor bank. The system-identification procedure involve
Externí odkaz:
https://doaj.org/article/fbef9eede9bb4f4a825e3af55fff4e21
Publikováno v:
Xenobiotica. 52:661-668
Prediction of rat, dog, monkey, and human volume of distribution (VD
Autor:
Ruoqi Liu, Katrin Georgi, David C. Thompson, Lena C. Preiss, Volker M. Lauschke, Carl Petersson, Lassina Badolo, Philip G. Hewitt
Publikováno v:
Drug Metabolism and Disposition. 49:668-678
Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and PXR/CAR knockout (KO) HepaRG cells, as well as a PXR reporter gene assay, were used to investigate the mechanism of CYP3A4 and CYP2B6 induction by prototypical substrates and a gr
Autor:
Carl Petersson, Xin Zhou, Joerg Berghausen, David Cebrian, Michael Davies, Kevin DeMent, Peter Eddershaw, Arian Emami Riedmaier, Alix F. Leblanc, Nenad Manveski, Punit Marathe, Panteleimon D. Mavroudis, Robin McDougall, Neil Parrott, Andreas Reichel, Charles Rotter, David Tess, Laurie P. Volak, Guangqing Xiao, Zheng Yang, James Baker
Publikováno v:
The AAPS journal. 24(5)
Accurate prediction of human clearance (CL) and volume of distribution at steady state (V
Publikováno v:
The AAPS journal. 24(2)
Accurate prediction of human pharmacokinetics using in vitro tools is an important task during drug development. Albeit, currently used in vitro systems for clearance extrapolation such as microsomes and primary human hepatocytes in suspension cultur
Autor:
Andrzej Gondela, Marcin Leś, Maciej Mikulski, Łukasz Włoszczak, Frank Becker, Kamila Olech, Shivapriya Ramaswamy, Marcin Król, Henryk Pawlik, Christian Herhaus, Jose Alvarez, Joanna Szczęśniak, Heike Schilke, Paulina Niedziejko, Lindsey Crowley, Roberta Ferretti, Mireille Krier, Pamela Wahra, Pia Böpple, Timo Heinrich, Justyna Martyka, Ewa Sitek, Karol Zuchowicz, Ada Sala-Hojman, Anna Bartosik, Stefano Minguzzi, Łukasz Dudek, Frank Czauderna, Mateusz Nowak, Ansgar Wegener, Michal Galezowski, Carl Petersson, Sven Jäckel
Publikováno v:
Journal of medicinal chemistry. 64(16)
Due to increased lactate production during glucose metabolism, tumor cells heavily rely on efficient lactate transport to avoid intracellular lactate accumulation and acidification. Monocarboxylate transporter 4 (MCT4/SLC16A3) is a lactate transporte
Autor:
Johan Winges, Tomas McKelvey, Lars-Ake Johansson, Thomas Rylander, Carl Petersson, Christian Ekman
Publikováno v:
Progress In Electromagnetics Research B. 83:25-42
© 2019 Progress In Electromagnetics Research B. We present an optimization procedure for wireless power transfer (WPT) applications and test it numerically for a WPT system design with four resonant circuits that are magnetically coupled by coaxial
Autor:
Dieter Dorsch, Nina Glaser, Eva Sherbetjian, Ulrich Graedler, Andreas Blum, Michael Busch, Nina Linde, Carl Petersson, Christina Esdar, Aaron Ruff
Publikováno v:
Cancer Research. 81:1482-1482
Oncogenic mutations in cKIT in exons 9 and 11 are the main driver of gastrointestinal stromal tumors (GIST). Imatinib is standard of care in 1L in unresectable metastatic or recurrent GIST, yet secondary resistance mutations in exons 13/14 and 17/18