Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Carl, Orr"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6384 (2023)
Psoriatic arthritis (PsA) is a systemic inflammatory condition characterised by multiple clinical manifestations. Over the last decade, significant progress has been made in understanding the pathobiology of the disease. An expanded set of targeted t
Externí odkaz:
https://doaj.org/article/40d4e12289404b5ea1864d614b63da12
Autor:
Aurélie Najm, Benoît Le Goff, Carl Orr, Rogier Thurlings, Juan D. Cañete, Frances Humby, Stefano Alivernini, Antonio Manzo, Søren Andreas Just, Vasco C. Romão, Veit Krenn, Ulf Müller-Ladner, Olga Addimanda, Sander W. Tas, Maria Stoenoiu, Laurent Meric de Bellefon, Patrick Durez, Vibeke Strand, Mihir D. Wechalekar, Joao E. Fonseca, Bernard Lauwerys, Ursula Fearon, Douglas J. Veale, on behalf of EULAR Synovitis Study Group and OMERACT Synovial Tissue Special Interest Group
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-7 (2018)
Abstract Background The aim of this global collaboration was to develop a consensual set of items for the analysis of synovial biopsies in clinical practice and translational research through the EULAR Synovitis Study Group (ESSG) and OMERACT Synovia
Externí odkaz:
https://doaj.org/article/15af29c76b704a1a978675fe89e9edff
Autor:
Clare C. Cunningham, Sarah Wade, Achilleas Floudas, Carl Orr, Trudy McGarry, Siobhan Wade, Sian Cregan, Ursula Fearon, Douglas J. Veale
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundMicroRNAs (miRNAs) are small non-coding RNAs which have been implicated as potential biomarkers or therapeutic targets in autoimmune diseases. This study examines circulatory miRNAs in RA patients and further investigates if a serum miRNA s
Externí odkaz:
https://doaj.org/article/97005a631c7646aa88935067eb0b04a6
Autor:
Emese Balogh, Douglas J. Veale, Trudy McGarry, Carl Orr, Zoltan Szekanecz, Chin-Teck Ng, Ursula Fearon, Monika Biniecka
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background In this study, we examined the effect of oxidative stress on cellular energy metabolism and pro-angiogenic/pro-inflammatory mechanisms of primary rheumatoid arthritis synovial fibroblast cells (RASFC) and human umbilical vein endo
Externí odkaz:
https://doaj.org/article/554844626c9b4bb1bbc275b2f6a94229
Autor:
Yanxia Guo, Alice M Walsh, Mary Canavan, Mihir D Wechalekar, Suzanne Cole, Xuefeng Yin, Brittney Scott, Mathew Loza, Carl Orr, Trudy McGarry, Michele Bombardieri, Frances Humby, Susanna M Proudman, Costantino Pitzalis, Malcolm D Smith, Joshua R Friedman, Ian Anderson, Loui Madakamutil, Douglas J Veale, Ursula Fearon, Sunil Nagpal
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192704 (2018)
Immune checkpoint blockade with therapeutic anti-cytotoxic T lymphocyte-associated antigen (CTLA)-4 (Ipilimumab) and anti-programmed death (PD)-1 (Nivolumab and Pembrolizumab) antibodies alone or in combination has shown remarkable efficacy in multip
Externí odkaz:
https://doaj.org/article/0245b0b04ea640cd937145e897e7feff
Autor:
Aurélie Najm, Benoît Le Goff, Carl Orr, Rogier Thurlings, Juan D. Cañete, Frances Humby, Stefano Alivernini, Antonio Manzo, Søren Andreas Just, Vasco C. Romão, Veit Krenn, Ulf Müller-Ladner, Olga Addimanda, Sander W. Tas, Maria Stoenoiu, Laurent Meric de Bellefon, Patrick Durez, Vibeke Strand, Mihir D. Wechalekar, Joao E. Fonseca, Bernard Lauwerys, Ursula Fearon, Douglas J. Veale, on behalf of EULAR Synovitis Study Group and OMERACT Synovial Tissue Special Interest Group
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-1 (2018)
Following publication of the original article [1], the authors reported an error in the spelling of the ninth author’s name.
Externí odkaz:
https://doaj.org/article/8226e2f3756e41bc81cfe2e17533b3df
Autor:
Matthew A Turk, Candice Low, Carl Orr, Richard Conway, Kieran Murray, Francis Young, Eamonn Molloy, Anne Barbara Mongey, Ursula Fearon, Douglas J. Veale
Background: To evaluate the clinical and laboratory factors associated with long-term responses to rituximab therapy in patients with RA. Methods: One hundred fourteen RA patients received intravenous Rituximab between 2003-2016. Prior to treatment,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3608f5a1f4d6707b0b252c02c92f94af
https://doi.org/10.21203/rs.3.rs-1275951/v2
https://doi.org/10.21203/rs.3.rs-1275951/v2
Autor:
Aurélie Najm, Félicie Costantino, Stefano Alivernini, Alessia Alunno, Elettra Bianchi, Jacqueline Bignall, Brendan Boyce, Juan D Cañete, Francesco Carubbi, Patrick Durez, João Eurico Fonseca, Søren Andreas Just, Raquel Largo, Antonio Manzo, Mark Maybury, Esperanza Naredo, Carl Orr, Costantino Pitzalis, Felice Rivellese, Vasco C Romão, Jef van Rompay, Sander W Tas, Douglas J Veale, Maria-Antonietta D'Agostino, Andrew Filer
Publikováno v:
Annals of the rheumatic diseases, Vol. 1, no.1, p. 1-7 (2022)
Annals of the rheumatic diseases, 81(12):221875, 1640-1646. BMJ Publishing Group
Annals of the rheumatic diseases, 81(12):221875, 1640-1646. BMJ Publishing Group
© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.
Background: Synovial tissue research has become widely developed in several rheumatology centres, however, large discrepancies exist in
Background: Synovial tissue research has become widely developed in several rheumatology centres, however, large discrepancies exist in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffffe9c41f2380a04618faaa28bf4efa
https://hdl.handle.net/10451/58072
https://hdl.handle.net/10451/58072
Autor:
Carl Orr, Michael G. Monaghan, Ursula Fearon, Ronan H Mullan, Mary Canavan, Douglas J. Veale, Conor Hurson, Nuno Neto, Achilleas Floudas, Phil Gallagher, Sunil Nagpar
Publikováno v:
Annals of the rheumatic diseases. 81(2)
ObjectivesThis study investigates pathogenic and protective polyfunctional T-cell responses in patient with rheumatoid arthritis (RA), individuals at risk (IAR) and healthy control (HC) synovial-tissue biopsies and identifies the presence of a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214b6c547cfd94f258f06b88c249be68
https://pubmed.ncbi.nlm.nih.gov/34598926
https://pubmed.ncbi.nlm.nih.gov/34598926
Autor:
Trudy McGarry, Douglas J. Veale, Carl Orr, Clare C. Cunningham, Achilleas Floudas, Sarah M. Wade, Ursula Fearon, Sian Cregan, S. Wade
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
BackgroundMicroRNAs (miRNAs) are small non-coding RNAs which have been implicated as potential biomarkers or therapeutic targets in autoimmune diseases. This study examines circulatory miRNAs in RA patients and further investigates if a serum miRNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3624f12896d4dc4b2f4bc9beb964ff7
https://pubmed.ncbi.nlm.nih.gov/33746971
https://pubmed.ncbi.nlm.nih.gov/33746971