Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Carl, Alpert"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56906 (2013)
Using a gnotobiotic mouse model, we previously observed the upregulation of 2-deoxy-D-gluconate 3-dehydrogenase (KduD) in intestinal E. coli of mice fed a lactose-rich diet and the downregulation of this enzyme and of 5-keto 4-deoxyuronate isomerase
Externí odkaz:
https://doaj.org/article/de7fab5cd156436a9ea2785032c1db52
Autor:
André Bleich, Michael Blaut, Sara Schumann, Gunnar Loh, Wolfram Engst, Robert Klopfleisch, Carl Alpert
Publikováno v:
Environmental Microbiology. 16:2966-2979
Using interleukin 10-deficient (IL-10(-/-) ) and wild-type mice monoassociated with either the adherent-invasive Escherichia coli UNC or the probiotic E. coli Nissle, the effect of a mild intestinal inflammation on the bacterial proteome was studied.
Publikováno v:
Applied and Environmental Microbiology. 78:3580-3591
To study the impact of nutritional factors on protein expression of intestinal bacteria, gnotobiotic mice monoassociated with Escherichia coli K-12 were fed three different diets: a diet rich in starch, a diet rich in nondigestible lactose, and a die
Autor:
Klaus J. Petzke, C Bumke-Vogt, Martin A. Osterhoff, Matthias Möhlig, Angela Kohl, Özlem Gögebakan, Ayman M. Arafat, Peter Nowotny, Anne-Kathrin Illner, Christian von Loeffelholz, Martin O. Weickert, D Hoffmann, Frank Isken, Johannes Hierholzer, Jürgen Machann, Friederike Mueller, Silke Hornemann, Michael Roden, Andreas Pfeiffer, Michael Blaut, Michael Kruse, Thomas M. Barber, Carl Alpert
Publikováno v:
The American Journal of Clinical Nutrition. 94:459-471
Despite their beneficial effects on weight loss and blood lipids, high-protein (HP) diets have been shown to increase insulin resistance and diabetes risk, whereas high-cereal-fiber (HCF) diets have shown the opposite effects on these outcomes.We com
Adaptation of protein expression byEscherichia coliin the gastrointestinal tract of gnotobiotic mice
Publikováno v:
Environmental Microbiology. 11:751-761
Summary The gastrointestinal tract of mammals is inhabited by several hundred bacterial species. While the effects of the gut microbiota upon the host have been widely studied, the microbial response to host factors has only recently attracted attent
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56906 (2013)
PLoS ONE
PLoS ONE
Using a gnotobiotic mouse model, we previously observed the upregulation of 2-deoxy-D-gluconate 3-dehydrogenase (KduD) in intestinal E. coli of mice fed a lactose-rich diet and the downregulation of this enzyme and of 5-keto 4-deoxyuronate isomerase
Autor:
Paul K. Ziegler, Melek C. Arkan, Shawn W. Polson, Andreas Böck, Jessica Heringer, Gabriela Salinas-Riester, Manon D. Schulz, Michael Blaut, W Reindl, Julia Varga, Florian R. Greten, Carl Alpert, Claudia Pommerenke, Begüm Aydin, Sarah Schwitalla, Thomas Kirchner, Çiğdem Atay, Franziska K. Romrig, Sara C. Polson, Lydia Brandl
Publikováno v:
Nature. 514(7523)
Several features common to a Western lifestyle, including obesity and low levels of physical activity, are known risk factors for gastrointestinal cancers. There is substantial evidence suggesting that diet markedly affects the composition of the int
Publikováno v:
Applied and environmental microbiology. 78(5)
To identify Escherichia coli proteins involved in adaptation to intestinal inflammation, mice were monoassociated with the colitogenic E. coli strain UNC or with the probiotic E. coli strain Nissle. Intestinal inflammation was induced by treating the
Publikováno v:
Applied and environmental microbiology. 76(15)
To study the adaptation of an intestinal bacterium to its natural environment, germfree mice were associated with commensal Escherichia coli MG1655. Two-dimensional gel electrophoresis was used to identify proteins differentially expressed in E. coli
Publikováno v:
Current issues in molecular biology. 10(1-2)
Human microbiota associated rats are frequently used as a model to study host microbe interactions. This study investigated the long-term stability of the bacterial community in such rats. Following the association of two strains of germ-free rats (1