Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.

Autor: Guirguis AA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia.; Department of Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, Victoria, Australia., Ofir-Rosenfeld Y; Storm Therapeutics Ltd, Cambridge, United Kingdom., Knezevic K; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Blackaby W; Storm Therapeutics Ltd, Cambridge, United Kingdom., Hardick D; Storm Therapeutics Ltd, Cambridge, United Kingdom., Chan YC; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Motazedian A; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Gillespie A; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Vassiliadis D; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Lam EYN; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Tran K; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Andrews B; Storm Therapeutics Ltd, Cambridge, United Kingdom., Harbour ME; Storm Therapeutics Ltd, Cambridge, United Kingdom., Vasiliauskaite L; Storm Therapeutics Ltd, Cambridge, United Kingdom., Saunders CJ; Storm Therapeutics Ltd, Cambridge, United Kingdom., Tsagkogeorga G; Storm Therapeutics Ltd, Cambridge, United Kingdom.; Milner Therapeutics Institute, University of Cambridge, Cambridge, United Kingdom., Azevedo A; Storm Therapeutics Ltd, Cambridge, United Kingdom., Obacz J; Storm Therapeutics Ltd, Cambridge, United Kingdom., Pilka ES; Evotec (UK) Ltd, Abingdon, United Kingdom., Carkill M; Charles River Laboratories, Portishead, United -Kingdom., MacPherson L; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Wainwright EN; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Liddicoat B; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Blyth BJ; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Albertella MR; Storm Therapeutics Ltd, Cambridge, United Kingdom., Rausch O; Storm Therapeutics Ltd, Cambridge, United Kingdom., Dawson MA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia.; Department of Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, Victoria, Australia.; Centre for Cancer Research, University of Melbourne, Melbourne, -Victoria, Australia.

Publikováno v: Cancer discovery [Cancer Discov] 2023 Oct 05; Vol. 13 (10), pp. 2228-2247.

Clinician's Guide to Epitranscriptomics: An Example of N 1 -Methyladenosine (m 1 A) RNA Modification and Cancer.

Autor: Kvolik Pavić, Ana^1,2 (AUTHOR) imumlek@gmail.com, Čonkaš, Josipa³ (AUTHOR) jconkas@irb.hr, Mumlek, Ivan² (AUTHOR), Zubčić, Vedran^1,2 (AUTHOR) zubcic.vedran@kbco.hr, Ozretić, Petar³ (AUTHOR) pozretic@irb.hr

Publikováno v: Life (2075-1729). Oct2024, Vol. 14 Issue 10, p1230. 18p.

Regulation of m 6 A Methylome in Cancer: Mechanisms, Implications, and Therapeutic Strategies.

Autor: Bhattarai, Poshan Yugal¹ (AUTHOR) poshanb@chosun.ac.kr, Kim, Garam¹ (AUTHOR), Bhandari, Dibikshya¹ (AUTHOR), Shrestha, Pratikshya¹ (AUTHOR), Choi, Hong Seok¹ (AUTHOR) chs@chosun.ac.kr

Publikováno v: Cells (2073-4409). Jan2024, Vol. 13 Issue 1, p66. 13p.