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pro vyhledávání: '"Carissa M. Heath"'
Autor:
Carissa M. Heath, Sarah M. Wignall
Publikováno v:
Molecular Biology of the Cell
Oocytes of many species lack centrioles and therefore form acentriolar spindles. Despite the necessity of oocyte meiosis for successful reproduction, how these spindles mediate accurate chromosome segregation is poorly understood. We have gained insi
Publikováno v:
Journal of Virology
These results provide the basis for the development of drugs that target enveloped virus budding that can be used ultimately to control multiple virus infections in humans.
In many enveloped virus families, including human immunodeficiency virus
In many enveloped virus families, including human immunodeficiency virus
In many enveloped virus families, including HIV and HSV, a crucial, yet unexploited, step in the viral life cycle is releasing particles from the infected cell membranes. This release process is mediated by host ESCRT complex proteins, which is recru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b746f47c20d8419e0bae2f74053acef5
https://doi.org/10.1101/2020.05.04.075036
https://doi.org/10.1101/2020.05.04.075036
Autor:
Sayantan Bose, Robert A. Lamb, Maher Alayyoubi, Priya A. Shah, Theodore S. Jardetzky, Carissa M. Heath
Publikováno v:
Journal of virology. 87(24)
Paramyxovirus membrane glycoproteins F (fusion protein) and HN, H, or G (attachment protein) are critical for virus entry, which occurs through fusion of viral and cellular envelopes. The F protein folds into a homotrimeric, metastable prefusion form