Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Carissa C. James"'
Autor:
Michael J. Zeitz, Patrick J. Calhoun, Carissa C. James, Thomas Taetzsch, Kijana K. George, Stefanie Robel, Gregorio Valdez, James W. Smyth
Publikováno v:
Cell Reports, Vol 27, Iss 9, Pp 2737-2747.e5 (2019)
Summary: Connexin43 (Cx43; gene name GJA1) is the most ubiquitously expressed gap junction protein, and understanding of its regulation largely falls under transcription and post-translational modification. In addition to Cx43, Gja1 mRNA encodes inte
Externí odkaz:
https://doaj.org/article/e390c97a0eb14226a53c300afdc81320
Autor:
Robert G. Gourdie, James W. Smyth, Carissa C. James, Gregory S. Hoeker, Allison N. Tegge, Steven Poelzing
Publikováno v:
Am J Physiol Heart Circ Physiol
Myocardial ischemia leads to conduction slowing, cell-to-cell uncoupling, and arrhythmias. We previously demonstrated that varying perfusate sodium (Na(+)) and calcium (Ca(2+)) attenuates conduction slowing and arrhythmias during simulated ischemia w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea19bf0c00d0184fb3dbdcc3bf8652a2
https://doi.org/10.1152/ajpheart.00112.2020
https://doi.org/10.1152/ajpheart.00112.2020
Publikováno v:
Mitochondrion
Complex I is the largest and most intricate of the protein complexes of mitochondrial electron transport chain (ETC). This L-shaped enzyme consists of a peripheral hydrophilic matrix domain and a membrane-bound orthogonal hydrophobic domain. The inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c575752b20866a9b564c588ebb3d5bb7
https://europepmc.org/articles/PMC8113094/
https://europepmc.org/articles/PMC8113094/
Autor:
Jordan D Taylor, Michael J. Zeitz, Rachel L Padget, James W. Smyth, Carissa C. James, Patrick J Calhoun, Allen V Phan
Publikováno v:
FASEB J
Adenoviruses are responsible for a spectrum of pathogenesis including viral myocarditis. The gap junction protein connexin43 (Cx43, gene name GJA1) facilitates rapid propagation of action potentials necessary for each heartbeat. Gap junctions also pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1175dc90ac040ed923d74c350ffd48c8
https://pubmed.ncbi.nlm.nih.gov/32485054
https://pubmed.ncbi.nlm.nih.gov/32485054
Autor:
James W. Smyth, Carissa C. James
Publikováno v:
Life Sciences. 212:138-144
Eukaryotic mRNAs were historically thought to rely exclusively on recognition and binding of their 5' cap by initiation factors to effect protein translation. While internal ribosome entry sites (IRESs) are well accepted as necessary for the cap-inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee894d6f7b808ae42757b74f2178b118
https://doi.org/10.1016/j.lfs.2018.09.054
https://doi.org/10.1016/j.lfs.2018.09.054
Publikováno v:
Circulation Research. 125
Introduction: Myocarditis leads to pathologic remodeling of the myocardium and arrhythmia. A leading etiological agent of viral myocarditis is human Adenovirus type 5 (Ad5). Individuals affected are at a higher risk of arrhythmogenesis which can lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef2588bf6c5294aa71effbb5b5d8293
https://doi.org/10.1161/res.125.suppl_1.505
https://doi.org/10.1161/res.125.suppl_1.505
Autor:
Carissa C. James, John C. Chappell, Huaning Zhao, Jordan Darden, James W. Smyth, Sarah Taylor, David McGuire, Laura Beth Payne
Publikováno v:
Microcirculation
Vascular pericytes provide critical contributions to the formation and integrity of the blood vessel wall within the microcirculation. Pericytes maintain vascular stability and homeostasis by promoting endothelial cell junctions and depositing extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce5ea74d17141175025866b4822eaaf
https://doi.org/10.1111/micc.12554
https://doi.org/10.1111/micc.12554
Publikováno v:
Molecular Biology of the Cell
Connexin43 mRNA can be internally translated to generate N-terminally truncated isoforms including GJA1-20k. GJA1-20k expression is suppressed during TGF-β–induced epithelial–mesenchymal transition, stabilizing full-length Connexin43 in the Golg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::372312dd9e32e2864bc8c96301509841
https://pubmed.ncbi.nlm.nih.gov/29467255
https://pubmed.ncbi.nlm.nih.gov/29467255
Epithelial–mesenchymal transition (EMT) is activated during development, wound healing, and pathologies including fibrosis and cancer metastasis. Hallmarks of EMT are remodeling of intercellular junctions and adhesion proteins, including gap juncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d6f1ba07869f409d0c59f06b5f3f8a
https://hdl.handle.net/10919/89722
https://hdl.handle.net/10919/89722
Publikováno v:
Biophysical Journal. 114:623a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5569156a2b0ee8c2ef7c68d836a91ef2
https://doi.org/10.1016/j.bpj.2017.11.3368
https://doi.org/10.1016/j.bpj.2017.11.3368