Zobrazeno 1 - 10
of 791
pro vyhledávání: '"Cariporide"'
Autor:
Shamseldin Ayman Hassan Metwally, Satya Siri Paruchuri, Lauren Yu, Okan Capuk, Nicholas Pennock, Dandan Sun, Shanshan Song
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13289 (2023)
To date, recanalization interventions are the only available treatments for ischemic stroke patients; however, there are no effective therapies for reducing stroke-induced neuroinflammation. We recently reported that H+ extrusion protein Na+/H+ excha
Externí odkaz:
https://doaj.org/article/6e918932ea8d4d4e9de51bb01f10dce5
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Doxorubicin (DOX) is a potent chemotherapeutic agent with limited usage due to its cumulative cardiotoxicity. The Na+/H+ exchanger isoform 1 (NHE1) is a known regulator of oxidative stress, inflammation, and apoptosis. The present study w
Externí odkaz:
https://doaj.org/article/6da447b0324340ec980f4c071f72e150
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background The Na+/H+ exchanger (NHE1) plays a crucial role in cancer cell proliferation and metastasis. However, the mechanism underlying chemotherapeutic resistance in cancer cells has not been completely elucidated. The NHE1 inhibitor car
Externí odkaz:
https://doaj.org/article/25c02605b7a04444815043d2f3c10c20
Autor:
Salameh, Aida, Zöbisch, Helena, Schröder, Bianca, Vigelahn, Jonas, Jahn, Mandy, Abraham, Getu, Seeger, Johannes, Dähnert, Ingo, Dhein, Stefan
Hypoxia often leads to severe cardiac malfunctions. It is assumed that intracellular calcium overload is -inter alia- responsible for left ventricular (LV) deterioration. Inhibition of the sodium-proton exchanger (NHE), which finally inhibits/slows c
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A84240
https://ul.qucosa.de/api/qucosa%3A84240/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A84240/attachment/ATT-0/
Autor:
Bartha, Maryam Mozaffari, Nivin N. Nyström, Alex Li, Miranda Bellyou, Timothy J. Scholl, Robert
Publikováno v:
Metabolites; Volume 13; Issue 7; Pages: 823
Acidification of cancerous tissue induced pharmacologically may slow tumor growth and can be detected using magnetic resonance imaging. Numerous studies have shown that pharmacologically inhibiting specific transporters, such as the Na+/H+ exchanger
Autor:
Jessica Iorio, Claudia Duranti, Tiziano Lottini, Elena Lastraioli, Giacomo Bagni, Andrea Becchetti, Annarosa Arcangeli
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Increasing evidence indicates that ion channels and transporters cooperate in regulating different aspects of tumor pathophysiology. In cancer cells, H+/HCO3- transporters usually invert the transmembrane pH gradient typically observed in non-neoplas
Externí odkaz:
https://doaj.org/article/821673a97a83469096644b119989f446
Autor:
Aida Salameh, Helena Zöbisch, Bianca Schröder, Jonas Vigelahn, Mandy Jahn, Getu Abraham, Johannes Seeger, Ingo Dähnert, Stefan Dhein
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Hypoxia often leads to severe cardiac malfunctions. It is assumed that intracellular calcium overload is -inter alia- responsible for left ventricular (LV) deterioration. Inhibition of the sodium-proton exchanger (NHE), which finally inhibits/slows c
Externí odkaz:
https://doaj.org/article/852e6df64eaf4cb2bcd2e8d776226593
Akademický článek
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Akademický článek
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