Výsledky vyhledávání

ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA

Autor: Ariana Huebner, James R. M. Black, Francesca Sarno, Roberto Pazo, Ignacio Juez, Laura Medina, Rocio Garcia-Carbonero, Carmen Guillén, Jaime Feliú, Carolina Alonso, Carlota Arenillas, Ana Belén Moreno-Cárdenas, Helena Verdaguer, Teresa Macarulla, Manuel Hidalgo, Nicholas McGranahan, Rodrigo A. Toledo

Publikováno v: Scientia

Circulating tumour DNA; Pancreatic cancer; Tumour evolution ADN tumoral circulant; Càncer de pàncrees; Evolució tumoral ADN tumoral circulante; Cáncer de páncreas; Evolución tumoral Background Liquid biopsies and the dynamic tracking of somatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a67a32fe0850e273f057c6ec8a4bf8
https://doi.org/10.1186/s13073-023-01171-w

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Standardization of Cell Culture Conditions and Routine Genomic Screening under a Quality Management System Leads to Reduced Genomic Instability in hPSCs

Autor: Francisco J. Molina-Ruiz, Clelia Introna, Georgina Bombau, Mireia Galofre, Josep M. Canals

Publikováno v: Cells; Volume 11; Issue 13; Pages: 1984

Human pluripotent stem cells (hPSCs) have generated unprecedented interest in the scientific community, given their potential applications in regenerative medicine, disease modeling, toxicology and drug screening. However, hPSCs are prone to acquire

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689eb951c77bc2d531048936605cab7f
http://hdl.handle.net/2445/195640

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Karyological study of some E Iberian threatened plants

Autor: Bosch i Daniel, Maria, Sáez, Llorenç, Simon Pallisé, Joan, Blanché i Vergés, Cèsar

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

In the framework of cytogenetic studies of rare and threatened plant species of the Catalan Countries and surrounding territories, a karyological study of some taxa - three populations of Delphinium bolosii and the only known one of D. mansanetianum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::402a8e1a0f4f452bf8cf0b352705120e
http://hdl.handle.net/2445/164093

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Generation of two compound heterozygous HGSNAT-mutated lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo C syndrome

Autor: Daniel Grinberg, María García-Morant, Edgar Creus-Bachiller, Isaac Canals, Noelia Benetó, Mónica Cozar, Lluïsa Vilageliu

Publikováno v: Stem Cell Research. 41:101616

Sanfilippo C syndrome (Mucopolysaccharidosis IIIC) is a rare lysosomal storage disorder caused by mutations in the HGSNAT gene. It is characterized by a progressive and severe neurodegeneration, for which there is no treatment available. Here, we rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a799264443e37b82554b6f028fc36e1
https://doi.org/10.1016/j.scr.2019.101616

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Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of TP53/ATM FISH deletions

Publikováno v: Oncotarget
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC

Genomic complexity identified by chromosome banding analysis (CBA) predicts a worse clinical outcome in CLL patients treated either with standard or new treatments. Herein, we analyzed the clinical impact of complex karyotypes (CK) with or without hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c33ee14ec31e9747ff312aaabe5987a
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6351

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Inversion polymorphism in two Serbian natural populations of Drosophila subobscura: Analysis of long-term changes

Autor: Francesc Mestres, Concepción Arenas, Goran Zivanovic

Publikováno v: Scopus-Elsevier
Russian Journal of Genetics
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Europe PubMed Central

To study whether inversions (or arrangements) by themselves or karyotypes are the main global warming adaptive target of natural selection, two Drosophila subobscura Serbian populations (Apatin and Petnica) were re-analyzed using different statistica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cface1f39cf1b53437a93d392ebd8bdc
https://doi.org/10.1134/s1022795414060155

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Short- and Long-Term Changes in Chromosomal Inversion Polymorphism and Global Warming: Drosophila Subobscura From the Balkans

Autor: Zivanovic, Goran, Arenas Solà, Concepción, Mestres i Naval, Francesc

Publikováno v: Israel Journal of Ecology & Evolution
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

The chromosomal inversion polymorphism of Drosophila subobscura is adaptive to environmental changes. The population of Petnica, Serbia, was chosen to analyze short- and long-term changes in this polymorphism. Short-term changes were studied in the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::692cb5f6580fd9c66cfcb9876d596ea4
http://ibiss-r.rcub.bg.ac.rs/123456789/1214

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DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia

Autor: Javier Suela, Juan C. Cigudosa, Alba Maiques, Agustín F. Fernández, Xabier Agirre, Manel Esteller, Sara Alvarez, Sandra Rodriguez Perales, Mark Wunderlich, Francesco Acquadro, Ana Valencia, José I. Martín-Subero, Felipe Prosper, Miguel A. Sanz, María José Calasanz, José Cervera, Reiner Siebert, Jose Roman-Gomez, James C. Mulloy

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Dadun. Depósito Académico Digital de la Universidad de Navarra
PLoS ONE
PLoS ONE, Vol 5, Iss 8, p e12197 (2010)

Background: Aberrant promoter DNA methylation has been shown to play a role in acute myeloid leukemia (AML) pathophysiology. However, further studies to discuss the prognostic value and the relationship of the epigenetic signatures with defined genom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87b20873a210cbac675f136a9161dd8
http://hdl.handle.net/2445/69603

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Caracterización citogenética molecular de algunos representantes de los subgéneros Artemisia y Absinthium (género Artemisia, Asteraceae)

Autor: Pellicer, J., Garcia, S., Garnatje, T., Hidalgo, O., Siljak-Yakovlev, S., Vallès, J.

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya
Collectanea Botanica; Vol. 27 (2008); 19-27
Collectanea Botanica
Consejo Superior de Investigaciones Científicas (CSIC)

9 pages, 2 tables, 1 figure.
A molecular cytogenetic study has been performed in three species of the genus Artemisia, complementing previous works on two subgenera that had been scarcely studied from this standpoint, Artemisia (A. chamaemelifol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1cd1dd0cf4ed022b544712fc11945dd2
http://hdl.handle.net/2445/32627

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Genetic characterization of Sezary's syndrome by conventional cytogenetics and cross-species color banding fluorescent in situ hybridization

Autor: Blanca Espinet, Salido, M., Pujol, R. M., Florensa, L., Gallardo, F., Domingo, A., Servitje, O., Estrach, T., García-Muret, P., Woessner, S., Serrano, S., Solé, F.

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Scopus-Elsevier

Background and objectives: Sezary's syndrome is a peripheral T-cell neoplasm characterized by a pruritic exfoliative or infiltrated erythroderma, lymphadenopathies, and atypical T lymphocytes in the peripheral blood. Cytogenetic studies are scarce. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5492f5650042630c7b06f52342705302
http://hdl.handle.net/2445/172770

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