Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Carinne Borges de Souza Moraes Rego Gomes"'
Autor:
Adrhyann Jullyanne de Sousa Portilho, Emerson Lucena da Silva, Emanuel Cintra Austregésilo Bezerra, Carinne Borges de Souza Moraes Rego Gomes, Vitor Ferreira, Maria Elisabete Amaral de Moraes, David Rodrigues da Rocha, Rommel Mário Rodriguez Burbano, Caroline Aquino Moreira-Nunes, Raquel Carvalho Montenegro
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8105 (2022)
The multidrug resistance (MDR) phenotype is one of the major obstacles in the treatment of chronic myeloid leukemia (CML) in advantage stages such as blast crisis. In this scenario, more patients develop resistance mechanisms during the course of the
Externí odkaz:
https://doaj.org/article/c4098d235a2644e9822c069e492282ca
Autor:
Ronaldo Rodrigues de Sousa, Carolina da Costa Lázaro, Carinne Borges de Souza Moraes Rego Gomes, Ayla Sant’Ana da Silva, Roberto Fernandez-Lafuente, Viridiana Santana Ferreira-Leitão
Publikováno v:
Process Biochemistry. 128:158-166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72c8d427e38a63b3ac8a73a8cec141e9
https://doi.org/10.1016/j.procbio.2023.02.030
https://doi.org/10.1016/j.procbio.2023.02.030
Autor:
Emerson Lucena da Silva, Felipe Pantoja Mesquita, Ingryd Nayara de Farias Ramos, Carinne Borges de Souza Moraes Rego Gomes, Caroline dos Santos Moreira, Vítor Francisco Ferreira, David Rodrigues da Rocha, Marcelo de Oliveira Bahia, Caroline Aquino Moreira-Nunes, Carolina Rosal Teixeira de Souza, Rommel Mario Rodrigues Burbano, Raquel Carvalho Montenegro
Publikováno v:
Toxicology and applied pharmacology. 456
Colorectal cancer (CRC) is estimated as the third most incident cancer and second in mortality worldwide. Moreover, CRC metastasis reduces patients' survival rates. Thus, the study and identification of new compounds with anticancer activity selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a42d240182ca7b3fd3f466d34179f9f
https://pubmed.ncbi.nlm.nih.gov/36208702
https://pubmed.ncbi.nlm.nih.gov/36208702
Autor:
Adrhyann Jullyanne de Sousa Portilho, Pâmella da Silva Cordeiro, Vanessa Nascimento, Caroline Aquino Moreira-Nunes, Luana da S. M. Forezi, Raquel Carvalho Montenegro, Caroline S. Moreira, Carinne Borges de Souza Moraes Rego Gomes, Maria Elisabete Amaral de Moraes, David R. da Rocha, Julio P. Daniel, Vitor F. Ferreira, Marne Carvalho de Vasconcellos
Publikováno v:
Computational Toxicology. 20:100197
In this work, 16 new thio-1,4-naphthoquinones were synthesized, and their antiproliferative effects against tumor cell lines SK-MEL-19, AGP-01, ACP-02, HL-60, K-562, K-562-Lucena-1, FEPS, and non-neoplastic human fibroblast MRC-5, were examined. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a64a39cef7981d73018eba566eee388f
https://doi.org/10.1016/j.comtox.2021.100197
https://doi.org/10.1016/j.comtox.2021.100197
Evaluation of 5-hydroxy-1,4-naphthoquinone-cobalt(III) complexes for hypoxia-activated drug delivery
Autor:
Gerardo Cebrián-Torrejón, Elaine Maria de Souza Fagundes, David R. da Rocha, Marcos Vinícius Palmeira de Mello, Glaucio B. Ferreira, Jonas Ramos Pereira, Caroline S. Moreira, Carinne Borges de Souza Moraes Rego Gomes, Mauricio Lanznaster
Publikováno v:
Journal of Inorganic Biochemistry. 199:110756
Three novel Py2N2-cobalt(III) complexes with the 5-hydroxy-1,4-naphthoquinone nuclei (NQ) were evaluated as potential hypoxia-activated anticancer prodrugs. The complexes were synthesized and fully characterized by IR and UV-Visible spectroscopies, E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44fcbe6a74e525ffa38c9cd20f5b8e5
https://doi.org/10.1016/j.jinorgbio.2019.110756
https://doi.org/10.1016/j.jinorgbio.2019.110756