Novel methodology to discern predictors of remission and patterns of disease activity over time using rheumatoid arthritis clinical trials data

Autor: Tom, BDM, Symmons, D, Brockbank, S, Carini, C, Cope, AP, Ehrenstein, MR, Fisher, BA, Goodyear, CS, Gozzard, N, Harris, R, Hicks, K, Hollis, S, Hughes-Morley, A, Isaacs, J, Kola, B, McInnes, IB, Mela, CM, Parker, G, Pedersen, AW, Ponchel, F, Sabin, T, Scott, DL, Scott, IC, Sleeman, MA, Taylor, PC, Tsuji, W, Zhong, Y, Hilkens, C, Anderson, A, Stocks, P, Lendrem, D, Tarn, J, Smith, G, Allen, B, Casement, J, Diboll, J, Harry, R, Simpson, G, Toward, R, Noble, H, Parke, A, Wu, W, Clarke, F, Galloway, J, Lempp, H, Ibrahim, F, Schwank, S, Molyneux, G, Lazarov, T, Geissmann, F, Donnelly, I, Gilmour, A, Virlan, AT, Porter, D, Emery, P, El-Jawhari, J, Parmar, R, McDermot, MF, Buch, M, Buckley, C, Young, SP, Jones, P, Raza, K, Filer, A, Pitzalis, C, Barnes, MR, Watson, DS, Tzanis, E, Thorborn, G, Fossati-Jimack, L, Kelly, S, Humby, F, Bombardieri, M, Rana, S, Jia, Z, Goldmann, K, Lewis, M, Altobelli, G, John, C, Martins, S, Nguyen, D, Ali, H, Ciurtin, C, Worthington, J, Bruce, IN, Sergeant, JC, Verstappen, SMM, Stirling, F, Farewell, V, Keidel, S, Cuff, C, Levesque, M, Long, A, Liu, Z, Lipsky, S, Harvey, B, Macoritto, M, Hong, F, Kaymakcalan, S, Ward, N, Talbot, S, Padhji, D, Sleeman, M, Finch, D, Herath, A, Lindholm, C, Jenkins, M, Ho, M, Marshall, C, Page, M, Edwards, H, Cuza, A, Rowe, A, Capdevila, FB, Loza, M, Curran, M, Verbeeck, D, Baker, D, Vranic, I, Mela, CT, Wright, S, Rowell, L, Vernon, E, Joseph, N, Payne, N, Rao, R, Binks, M, Belson, A, Ludbrook, V, Tipney, H, Ellis, J, Hasan, S, Didierlaurent, A, Burny, W, Haynes, A, Larminie, C, Dastros-Pitel, D, Jelinsky, S, Hodge, M, Maciejewski, M, Ziemek, D, Schulz-Knappe, P, Zucht, H-D, Budde, P, Coles, MC, Butler, JA, Read, S, Consortium, RA-MAP

Objectives: To identify predictors of remission and disease activity patterns in patients with rheumatoid arthritis (RA) using individual participant data (IPD) from clinical trials. Methods: Phase II and III clinical trials completed between 2002 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::4ac11814e901364bf7dcec578a58a963
https://eprints.whiterose.ac.uk/143215/11/e000721.full.pdf

Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium

Autor: Rup, B, Pallardy, M, Sikkema, D, Albert, T, Allez, M, Broet, P, Carini, C, Creeke, P, Davidson, J, De Vries, N, Finco, D, Fogdell-Hahn, A, Havrdova, E, Hincelin-Mery, A, C Holland, M, H Jensen, P E, Jury, E C, Kirby, H, Kramer, D, Lacroix-Desmazes, S, Legrand, J, Maggi, E, Maillère, B, Mariette, X, Mauri, C, Mikol, V, Mulleman, D, Oldenburg, J, Paintaud, G, R Pedersen, C, Ruperto, N, Seitz, R, Spindeldreher, S, Deisenhammer, F

Publikováno v: Clinical and Experimental Immunology

Biopharmaceuticals (BPs) represent a rapidly growing class of approved and investigational drug therapies that is contributing significantly to advancing treatment in multiple disease areas, including inflammatory and autoimmune diseases, genetic def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1874cb3a7cbe367bc8c7f28b72d2eeb7
http://europepmc.org/articles/PMC4557374

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A new role for interleukin-7 in the induction of LFA-1 and VLA-4 adhesion molecules in Phorbol ¹²myristate ¹³acetate activated CD4⁺CD23⁺ T-cell subset.

Autor: Fratazzi, C.¹, Carini, C.²

Publikováno v: Clinical & Experimental Allergy. Nov1997, Vol. 27 Issue 11, p1335-1343. 9p.

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