Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carine Winkler"'
Autor:
Patrick Meylan, Christine Pich, Carine Winkler, Stefanie Ginster, Lionel Mury, Marie Sgandurra, René Dreos, Dennie Tompers Frederick, Marc Hammond, Genevieve Marie Boland, Liliane Michalik
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The thioredoxin system plays key roles in regulating cancer cell malignancy. Here we identify the Thioredoxin-interacting protein (TXNIP) as a gene, which expression is regulated by PPARγ in melanoma cells. We show that high TXNIP expressio
Externí odkaz:
https://doaj.org/article/afba53c8238a4f37922879d894340072
Autor:
Maria-Bernadette Madel, He Fu, Dominique D. Pierroz, Mariano Schiffrin, Carine Winkler, Anne Wilson, Cécile Pochon, Barbara Toffoli, Mahdia Taïeb, Jean-Yves Jouzeau, Federica Gilardi, Serge Ferrari, Nicolas Bonnet, Claudine Blin-Wakkach, Béatrice Desvergne, David Moulin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Long bones from mammals host blood cell formation and contain multiple cell types, including adipocytes. Physiological functions of bone marrow adipocytes are poorly documented. Herein, we used adipocyte-deficient PPARγ-whole body null mice to inves
Externí odkaz:
https://doaj.org/article/b53b90ec113941678457684bbb7bf3ca
Autor:
Mariano Schiffrin, Carine Winkler, Laure Quignodon, Aurélien Naldi, Martin Trötzmüller, Harald Köfeler, Hugues Henry, Paolo Parini, Béatrice Desvergne, Federica Gilardi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9969 (2021)
Men with nonalcoholic fatty liver disease (NAFLD) are more exposed to nonalcoholic steatohepatitis (NASH) and liver fibrosis than women. However, the underlying molecular mechanisms of NALFD sex dimorphism are unclear. We combined gene expression, hi
Externí odkaz:
https://doaj.org/article/fa81b10b1f3e4f689e7cd6b6a437344d
Autor:
Anne Wilson, He Fu, Mariano Schiffrin, Carine Winkler, Meriem Koufany, Jean-Yves Jouzeau, Nicolas Bonnet, Federica Gilardi, François Renevey, Sanjiv A. Luther, David Moulin, Béatrice Desvergne
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Adult hematopoiesis takes place in the perivascular zone of the bone cavity, where endothelial cells, mesenchymal stromal/stem cells and their derivatives such as osteoblasts are key components of bone marrow (BM) niches. Defining the contribution of
Externí odkaz:
https://doaj.org/article/830f18bf1dc14880a4039984b850a53a
Autor:
Barbara Toffoli, Federica Gilardi, Carine Winkler, Magnus Soderberg, Laura Kowalczuk, Yvan Arsenijevic, Krister Bamberg, Olivier Bonny, Béatrice Desvergne
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171474 (2017)
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-dependent transcription factor involved in many aspects of metabolism, immune response, and development. Total-body deletion of the two Pparg alleles provoked generalized lipoatrophy
Externí odkaz:
https://doaj.org/article/4ff6c1385d6148348a565d93def9243d
Autor:
Gabriele Dammone, Sonia Karaz, Laura Lukjanenko, Carine Winkler, Federico Sizzano, Guillaume Jacot, Eugenia Migliavacca, Alessio Palini, Béatrice Desvergne, Federica Gilardi, Jerome N. Feige
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 2044 (2018)
Skeletal muscle is a regenerative tissue which can repair damaged myofibers through the activation of tissue-resident muscle stem cells (MuSCs). Many muscle diseases with impaired regeneration cause excessive adipose tissue accumulation in muscle, al
Externí odkaz:
https://doaj.org/article/f0dad2e6b3ed4c36828ba16715e6c873
Autor:
Van Du T. Tran, Gabriela Aguileta, Béatrice Desvergne, Aurélien Thomas, Nasim Bararpour, Carine Winkler, Anne Wilson, Nicolas Guex, Greta Maria Paola Giordano Attianese, Marco Pagni, Federica Gilardi, Khanh B. Trang, Tiziana Caputo
Publikováno v:
Cellular and molecular life sciences, vol. 78, no. 1, pp. 227-247
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences
Chronic inflammation that affects primarily metabolic organs, such as white adipose tissue (WAT), is considered as a major cause of human obesity-associated co-morbidities. However, the molecular mechanisms initiating this inflammation in WAT are poo
Autor:
Jean-Gael Diserens, Laure Quignodon, Federica Gilardi, Chiara Sardella, Béatrice Desvergne, Barbara Toffoli, Frédéric Preitner, Carine Winkler, Mariano Schiffrin
Publikováno v:
Metabolism, vol. 95, pp. 8-20
The peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-dependent transcription factor involved in many aspects of metabolism, immune response and development. Numerous studies relying on tissue-specific invalidation of the Pparg gene
Autor:
Christine Pich, René Dreos, Marie Sgandurra, Patrick Meylan, Liliane Michalik, Stefanie Ginster, Genevieve M. Boland, Lionel Mury, Carine Winkler, Marc R. Hammond, Dennie T. Frederick
Publikováno v:
Scientific reports, vol. 11, no. 1, pp. 7847
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
The thioredoxin system plays key roles in regulating cancer cell malignancy. Here we identify the Thioredoxin-interacting protein (TXNIP) as a gene, which expression is regulated by PPARγ in melanoma cells. We show that high TXNIP expression levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3232c3b364e309b63b97919bebfaf8
https://serval.unil.ch/resource/serval:BIB_E6198EE2A6D0.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_E6198EE2A6D0.P001/REF.pdf
Autor:
Béatrice Desvergne, Mariano Schiffrin, Cécile Pochon, Serge Ferrari, D. D. Pierroz, David Moulin, Barbara Toffoli, Nicolas Bonnet, He Fu, Jean-Yves Jouzeau, Anne Wilson, Maria-Bernadette Madel, Claudine Blin-Wakkach, Federica Gilardi, Carine Winkler
Summary Long bones from mammals host blood cell formation and contain multiple cell types, including adipocytes. Overabundance of adipocytes in bone marrow is associated with pathological conditions such as age-related osteoporosis or marrow aplasia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb1750d234860147b63ce63fb076024