Correction: The translesion DNA polymerases Pol ζ and Rev1 are activated independently of PCNA ubiquitination upon UV radiation in mutants of DNA polymerase δ.

Autor: Carine Tellier-Lebegue, Eléa Dizet, Emilie Ma, Xavier Veaute, Eric Coïc, Jean-Baptiste Charbonnier, Laurent Maloisel

Publikováno v: PLoS Genetics, Vol 14, Iss 2, p e1007236 (2018)

[This corrects the article DOI: 10.1371/journal.pgen.1007119.].

Externí odkaz: https://doaj.org/article/ba4343d950c641c28f528ae2004ba97d

Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation

Autor: Lepakshi Ranjha, Pierre Chervy, Valérie Borde, Marie-Hélène Le Du, Laurent Maloisel, Jean-Baptiste Charbonnier, Giordano Reginato, Aurélien Thureau, Virginie Ropars, Emmanuelle Martini, Pierre Legrand, Jessica Andreani, Aurore Sanchez, Céline Adam, Petr Cejka, Jingqi Dai, Raphael Guerois, Carine Tellier-Lebegue

Publikováno v: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (23), pp.e2022704118. ⟨10.1073/pnas.2022704118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (23), pp.e2022704118. ⟨10.1073/pnas.2022704118⟩

International audience; In budding yeast, the MutL homolog heterodimer Mlh1-Mlh3 (MutLγ) plays a central role in the formation of meiotic crossovers. It is also involved in the repair of a subset of mismatches besides the main mismatch repair (MMR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b3a333390522239b86cd01d2b897bf
https://europepmc.org/articles/PMC8201911/

The translesion DNA polymerases Pol ζ and Rev1 are activated independently of PCNA ubiquitination upon UV radiation in mutants of DNA polymerase δ

Autor: Carine Tellier-Lebegue, Eléa Dizet, Emilie Ma, Xavier Veaute, Eric Coïc, Jean-Baptiste Charbonnier, Laurent Maloisel

Publikováno v: PLoS Genetics
PLoS Genetics, Public Library of Science, 2018, 14 (2), pp.e1007236. ⟨10.1371/journal.pgen.1007236⟩
PLoS Genetics, 2018, 14 (2), pp.e1007236. ⟨10.1371/journal.pgen.1007236⟩
PLoS Genetics, Vol 14, Iss 2, p e1007236 (2018)

Replicative DNA polymerases cannot insert efficiently nucleotides at sites of base lesions. This function is taken over by specialized translesion DNA synthesis (TLS) polymerases to allow DNA replication completion in the presence of DNA damage. In e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693b2d365fe39430e36216febeab8ddb
https://hal.archives-ouvertes.fr/hal-02184421

PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF

Autor: Carine Tellier-Lebegue, Katheryn Meek, Mauro Modesti, Clément Nemoz, Satish K. Tadi, Jean-Baptiste Charbonnier, Stéphane Audebert, Sunetra Roy, Pascal Drevet

Publikováno v: Cell Reports
Cell Reports, Elsevier Inc, 2016, 17 (2), pp.541-555. ⟨10.1016/j.celrep.2016.09.026⟩
Cell Reports, Vol 17, Iss 2, Pp 541-555 (2016)
Cell Reports, 2016, 17 (2), pp.541-555. ⟨10.1016/j.celrep.2016.09.026⟩

International audience; In mammalian cells, classical non-homologous end joining (c-NHEJ) is critical for DNA double-strand break repair induced by ionizing radiation and during V(D)J recombination in developing B and T lymphocytes. Recently, PAXX wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac7cb99d53d9d5a0dc79c58b7fa1f5b
https://www.hal.inserm.fr/inserm-01401845/document

Structural analysis of the Smad2-MAN1 interaction that regulates transforming growth factor-β signaling at the inner nuclear membrane

Autor: Wikayatou Attanda, Jean-Baptiste Charbonnier, Bernard Gilquin, Sophie Zinn-Justin, Sylvaine Gasparini, Wei Wu, Howard J. Worman, Benjamin Bourgeois, Carine Tellier-Lebegue, Javier Pérez, Emilie Kondé, Sandrine Caputo

Publikováno v: Biochemistry
Biochemistry, American Chemical Society, 2010, pp.8020-8032. ⟨10.1021/bi101153w⟩
Biochemistry, 2010, 49, pp.8020-8032. ⟨10.1021/bi101153w⟩

MAN1, an integral protein of the inner nuclear membrane, influences transforming growth factor-β (TGF-β) signaling by directly interacting with R-Smads. Heterozygous loss of function mutations in the gene encoding MAN1 cause sclerosing bone dysplas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac574b8082695a2f7058af2c438619f
https://hal.archives-ouvertes.fr/hal-00583792