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pro vyhledávání: '"Carine Raquel Richter Schmitz"'
Autor:
Carine Raquel Richter Schmitz, Rafael Moura Maurmann, Fatima T. C. R. Guma, Moisés Evandro Bauer, Florencia Maria Barbé-Tuana
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Aging is associated with an increased incidence of autoimmune diseases, despite the progressive decline of immune responses (immunosenescence). This apparent paradox can be explained by the age-related chronic low-grade systemic inflammation (inflamm
Externí odkaz:
https://doaj.org/article/afd6178a898243d6bedaae15a81ebd27
Autor:
Carine Raquel Richter Schmitz, Giselle A. Funchal, Moisés Evandro Bauer, Florencia María Barbé-Tuana, Rafael Moura Maurmann
Publikováno v:
Seminars in Immunopathology
The aging immune system (immunosenescence) has been implicated with increased morbidity and mortality in the elderly. Of note, T cell aging and low-grade inflammation (inflammaging) are implicated with several age-related conditions. The expansion of
Autor:
Viviane Glaser, Jovani Antônio Steffani, Aline Pertile Remor, Karina Giacomini Varela, Carine Raquel Richter Schmitz, Maria Victória Branco Flores, Tuany Eichwald, Diego de Carvalho, Analu Mantovani
Publikováno v:
Regulatory Toxicology and Pharmacology. 104:98-107
Introduction Manganese (Mn) is an essential element required for several biological systems. However, it is toxic in excessive accumulation. The toxic effects following Mn overexposure is well known in the CNS but other studies evaluating other targe
Autor:
Bruno de Souza Basso, Maria Claudia Rosa Garcia, Luiz Augusto Basso, Gabriela Viegas Haute, Márcio Vinícius Fagundes Donadio, Géssica Luana Antunes, Elisa Feller Gonçalves da Silva, Marcella Tornquist Nassr, Carine Raquel Richter Schmitz, Pablo Machado, Vitor Giancarlo Schneider Levorse, Leonardo Pfeiff Carlessi, Carolina Luft, Matheus Scherer Bastos, Jarbas Rodrigues de Oliveira, Eliane Romanato Santarém, Bruna Pasqualotto Costa, Florencia María Barbé-Tuana, Krist Helen Antunes Fernandes, Camille Kirinus Reghelin
Publikováno v:
European journal of pharmacology. 890
Potassium 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-olate (CPBMF65) is a potent inhibitor of the uridine phosphorylase 1 (UPP1) enzyme. Its non-ionized analog has already demonstrated biological properties by reducing adverse effects caused by the