Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Carine Parent"'
Autor:
Randriely Merscher Sobreira de Lima, Barbara Barth, Danusa Mar Arcego, Euclides José de Mendonça Filho, Sachin Patel, Zihan Wang, Irina Pokhvisneva, Carine Parent, Robert D. Levitan, Michael S. Kobor, Ana Paula Santana de Vasconcellos Bittencourt, Michael J. Meaney, Carla Dalmaz, Patrícia Pelufo Silveira
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
An expression-based polygenic risk score analysis of leptin receptor (LepR) genes suggests that LepR-specific genes co-expressed in the prefrontal cortex interact with exposure to postnatal adversity, potentially modulating eating behavior in childre
Externí odkaz:
https://doaj.org/article/d0b673224a9942d6a2306ea8eb546f0c
Autor:
Aashita Batra, Lawrence M. Chen, Zihan Wang, Carine Parent, Irina Pokhvisneva, Sachin Patel, Robert D. Levitan, Michael J. Meaney, Patricia Pelufo Silveira
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
While the co-morbidity between metabolic and psychiatric behaviors is well-established, the mechanisms are poorly understood, and exposure to early life adversity (ELA) is a common developmental risk factor. ELA is associated with altered insulin sen
Externí odkaz:
https://doaj.org/article/e0214ed692f94cf5beed26285244e4db
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
Pre-natal exposure to acute maternal trauma or chronic maternal distress can confer increased risk for psychiatric disorders in later life. Acute maternal trauma is the result of unforeseen environmental or personal catastrophes, while chronic matern
Externí odkaz:
https://doaj.org/article/54e1068eca2641d8909b0b62e976ec54
Autor:
Nirmala Arul Rayan, Vibhor Kumar, Jonathan Aow, Naghmeh Rastegar, Michelle Gek Liang Lim, Nicholas O’Toole, Edita Aliwarga, Danusa Mar Arcego, Hui Ting Grace Yeo, Jen Yi Wong, May Yin Lee, Florian Schmidt, Hajira Shreen Haja, Wai Leong Tam, Tie-Yuan Zhang, Josie Diorio, Christoph Anacker, Rene Hen, Carine Parent, Michael J Meaney, Shyam Prabhakar
Publikováno v:
Molecular Psychiatry. 27:4510-4525
Depression and anxiety are major global health burdens. Although SSRIs targeting the serotonergic system are prescribed over 200 million times annually, they have variable therapeutic efficacy and side effects, and mechanisms of action remain incompl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc06ddc305fbbd950921fb8126b2e3c
https://doi.org/10.1038/s41380-022-01725-1
https://doi.org/10.1038/s41380-022-01725-1
Autor:
Nathan R. Einhorn, Xianglan Wen, Huda Akil, Bruce S. McEwen, Francis S. Lee, Nicholas O’Toole, Michael J. Meaney, Jordan Marrocco, Mojun Shen, Carine Parent, Tie-Yuan Zhang, Salvatore G. Caradonna, Huzefa Khalil
Publikováno v:
Neuropsychopharmacology. 47:987-999
The multifactorial etiology of stress-related disorders necessitates a constant interrogation of the molecular convergences in preclinical models of stress that use disparate paradigms as stressors spanning from environmental challenges to genetic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff6723d1013284d797a15b5d048fce2
https://doi.org/10.1038/s41386-021-01219-8
https://doi.org/10.1038/s41386-021-01219-8
Autor:
Danielle Hessler, Victoria Keeton, Nancy E. Adler, Michael J. Meaney, Holly Wing, Kieran J. O’Donnell, Carine Parent, Gladi Thng, Patrícia Pelufo Silveira, Michelle Z. L. Kee, Euclides José de Mendonça Filho, Irina Pokhvisneva, Matthew S. Pantell, Laura M. Gottlieb
Publikováno v:
Brain, Behavior, and Immunity. 94:125-137
Some individuals exposed to early life stress show evidence of enhanced systemic inflammation and are at greater risk for psychopathology. In the current study, caregivers and their offspring (0–17 years) were recruited at a pediatric clinic visit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d790cc8eabd17161bf018a4bebc6b816
https://doi.org/10.1016/j.bbi.2021.02.025
https://doi.org/10.1016/j.bbi.2021.02.025
Autor:
Barbara Barth, Danusa Arcego Mar, Euclides José de Mendonça Filho, Randriely Merscher Sobreira de Lima, Sachin Patel, Omar Khedr, Zihan Wang, Carine Parent, Carla Dalmaz, André Krumel Portella, Irina Pokhvisneva, Michael J Meaney, Patricia Pelufo Silveira
Psychiatric and cardio-metabolic conditions are commonly comorbid, being a leading cause of disability. Early adversity is a risk factor for both conditions, however, biological pathways remain unknown. The dopamine (DA) system is sensitive to early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d377383b4d5887ce12f40faa4cb6f82
https://doi.org/10.1101/2022.04.23.22274209
https://doi.org/10.1101/2022.04.23.22274209
Autor:
Michael J. Meaney, Irina Pokhvisneva, Carine Parent, Hélène Gaudreau, Patrícia Pelufo Silveira
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 58:1115-1123
Objective The Avon Longitudinal Study of Parents and Children (ALSPAC) and Maternal Adversity, Vulnerability and Neurodevelopment (MAVAN) cohorts were used to determine whether repeated exposure to gastroenteritis in early life could predict risk for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7281013eedd432d20fd907ab4dd11be6
https://doi.org/10.1016/j.jaac.2019.01.007
https://doi.org/10.1016/j.jaac.2019.01.007
Autor:
Lawrence M. Chen, Julia L. MacIsaac, Sherif Karama, Hélène Gaudreau, Irina Pokhvisneva, Michael S. Kobor, Kieran J. O’Donnell, Andrée-Anne Bouvette-Turcot, Mavan Study Team, Marieke S. Tollenaar, Roseriet Beijers, Carine Parent, Michael J. Meaney, Patrícia Pelufo Silveira, Carolina de Weerth, Josie Diorio, Lisa M. McEwen, Shantala A. Hari Dass
Publikováno v:
DEV PSYCHOPATHOL, 32(5), 1810-1821. CAMBRIDGE UNIV PRESS
Development and Psychopathology, 32, 1810-1821
Development and Psychopathology, 32, 5, pp. 1810-1821
Development and Psychopathology, 32, 1810-1821
Development and Psychopathology, 32, 5, pp. 1810-1821
Maternal antenatal depression strongly influences child mental health but with considerable inter-individual variation that is, in part, linked to genotype. The challenge is to effectively capture the genotypic influence. We outline a novel approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f80dc2ecc0e25ddcdf2207d338caafd
http://hdl.handle.net/1887/3250326
http://hdl.handle.net/1887/3250326
Autor:
Marius Lahti-Pulkkinen, Kieran J. O’Donnell, Irina Pokhvisneva, Katri Räikkönen, Michael J. Meaney, Tuomas Kvist, Vivette Glover, Patrícia Pelufo Silveira, Thomas G. O'Connor, Lawrence M. Chen, Carine Parent, Jari Lahti
Publikováno v:
SSRN Electronic Journal.
Background: There is considerable evidence for an association between antenatal maternal symptoms of depression and anxiety and an increased risk for child mental health problems. One possible major factor that has not been given significant attentio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e94fff7ca093e72e44067a38bc2dec8a
https://doi.org/10.2139/ssrn.3837272
https://doi.org/10.2139/ssrn.3837272