Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carine Mounier"'
Autor:
Serena Diazzi, Alberto Baeri, Julien Fassy, Margaux Lecacheur, Oskar Marin‐Bejar, Christophe A Girard, Lauren Lefevre, Caroline Lacoux, Marie Irondelle, Carine Mounier, Marin Truchi, Marie Couralet, Mickael Ohanna, Alexandrine Carminati, Ilona Berestjuk, Frederic Larbret, David Gilot, Georges Vassaux, Jean‐Christophe Marine, Marcel Deckert, Bernard Mari, Sophie Tartare‐Deckert
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 3, Pp n/a-n/a (2022)
Abstract Lineage dedifferentiation toward a mesenchymal‐like state displaying myofibroblast and fibrotic features is a common mechanism of adaptive and acquired resistance to targeted therapy in melanoma. Here, we show that the anti‐fibrotic drug
Externí odkaz:
https://doaj.org/article/671e1303a548439c811055b9bfe4b17f
Autor:
M.-A. Dagnelie, Brigitte Dréno, Amir Khammari, Emmanuel Montassier, Stéphane Corvec, Carine Mounier
Publikováno v:
Experimental dermatology. 28(8)
Acne is the most common inflammatory skin disease, affecting up to 85% of the 11-30 years old world population. Skin microbiota appears as a key player involved in several skin dermatoses physiopathology. Here, we show that inflammatory skin is assoc
Autor:
Yves Rival, B. Chignon-Sicard, Robert Ballotti, Bruno Mehul, Florence Joly, Carine Marty, Claire Regazzetti, Pascale Reiniche, Thierry Passeron, M. Cavalié, Johannes Voegel, Michel Rivier, David Piwnica, Carine Mounier
Publikováno v:
The Journal of investigative dermatology
Vitiligo affects 1% of the worldwide population. Halting disease progression and repigmenting the lesional skin represent the two faces of therapeutic challenge in vitiligo. We performed transcriptome analysis on lesional, perilesional, and non-depig
Autor:
Sophie Deret, Carine Mounier, Florence Joly, Francesca Zolezzi, Bastien Gamboa, Corinne Ménigot, John T. Lear, Jérôme Aubert, Farzaneh Sidou, Pascale Reiniche, Johannes Voegel, Anthony A. Fryer, Paul Fogel
Publikováno v:
Journal of dermatological science.
Background Actinic keratoses (AK) are proliferations of neoplastic keratinocytes in the epidermis resulting from cumulative exposure to ultraviolet radiation (UVR), which are liable to transform into squamous cell carcinoma (SCC). Organ Transplant Re
Autor:
Brigitte Dréno, Jérôme Aubert, Etienne Thoreau, P. Rosso, Carine Mounier, Jonathan Pascau, Michel Rivier, Emmanuel Vial, Johannes Voegel, B. Bertino, I. Pelisson, T. Portal, Isabelle Carlavan, Sophie Deret, A.P. Luzy, S. Blanchét-Rethore
Publikováno v:
Journal of Investigative Dermatology. 138:B17
Autor:
Nadia Meddad-Bel Habich, Jean-Edouard Ombetta, Aazdine Lamouri, Françoise Heymans, Léon Assogba, Azali Ahamada-Himidi, Chang-Zhi Dong, Jean-Jacques Godfroid, Darina Aoun, Jack Huet, Latifa Boukli, Carine Mounier
Publikováno v:
European Journal of Medicinal Chemistry. 40:850-861
Starting from 4-tetradecyloxybenzamidine ( PMS815 ), a non-specific inhibitor of GI and GII PLA 2 s, we report in this work the discovery of the specificity through design, synthesis and structure–activity relationships studies of different kinds o
Publikováno v:
FEBS Letters. 471:12-16
Anandamide (ANA), a cannabinoid receptor ligand, stimulated platelet aggregation at concentrations similar to those of arachidonic acid (AA). The aggregating effect of ANA was inhibited by aspirin but not by SR-141716, a cannabinoid receptor antagoni
Autor:
John H. Griffin, Francis Schaeffer, Carine Mounier, Grazyna Faure, Tilman M. Hackeng, Cassian Bon
Publikováno v:
Journal of Biological Chemistry. 273:23764-23772
Human group II secretory phospholipase A2 (hsPLA2) exhibits significant anticoagulant activity that does not require its enzymatic activity. We examined which coagulation factor was targeted by hsPLA2 and analyzed which region of the protein may be i
Publikováno v:
European Journal of Biochemistry. 237:778-785
Blood platelets play a central role in haemostasis by leading to plug formation and by increasing the efficiency of blood coagulation. We have previously shown that blood platelets contain a group II secretory phospholipase A2 (sPLA2 grII) which is r
Autor:
Cassian Bon, Hubertus M. Verheij, Lhousseine Touqui, Peet A. Franken, B. Boris Vargaftig, Carine Mounier
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1214:88-96
The ability of platelet secretory phospholipase A2 (sPLA2) to induce platelet activation was investigated. sPLA2 (group II) contained in an activated platelet supernatant, as well as high concentrations of purified recombinant platelet sPLA2, failed