Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Carine M Boustany"'
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
Externí odkaz:
https://doaj.org/article/2e61fb2ee39746faa2d30dc3f23407d9
Autor:
Stephen eOrena, Tristan eMaurer, Rena eEudy, Li eShe, Darla eDash, Paula eLoria, Mary Ellen eBanker, Vincent eBernardo, Meera eTugnait, Carlin eOkerberg, Jessie eQian, Carine M Boustany-Kari
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
The mineralocorticoid receptor (MR) antagonists PF 03882845 and eplerenone were evaluated for renal protection against aldosterone mediated renal disease in uninephrectomized Sprague Dawley (SD) rats maintained on a high salt diet and receiving aldos
Externí odkaz:
https://doaj.org/article/600f14b8dfbc45138544c2ea1bcd1506
Autor:
Anissa A. Widjaja, Sivakumar Viswanathan, Shamini G. Shekeran, Eleonora Adami, Wei-Wen Lim, Sonia Chothani, Jessie Tan, Joyce Wei Ting Goh, Hui Mei Chen, Sze Yun Lim, Carine M. Boustany-Kari, Julie Hawkins, Enrico Petretto, Norbert Hübner, Sebastian Schafer, Thomas M. Coffman, Stuart A. Cook
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Repair processes in kidney are impaired in severe disease. Here, the authors show that in kidney failure, genetic or pharmacologic inhibition of IL11 releases the brake on regeneration, reverses tissue damage and restores kidney function.
Externí odkaz:
https://doaj.org/article/60e0f4d907fc4280bc1f88c1b900af64
Autor:
Lorena Pantano, George Agyapong, Yang Shen, Zhu Zhuo, Francesc Fernandez-Albert, Werner Rust, Dagmar Knebel, Jon Hill, Carine M. Boustany-Kari, Julia F. Doerner, Jörg F. Rippmann, Raymond T. Chung, Shannan J. Ho Sui, Eric Simon, Kathleen E. Corey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. In adults with NAFLD, fibrosis can develop and progress to liver cirrhosis and liver failure. However, the underlying molecular mechanisms of fibr
Externí odkaz:
https://doaj.org/article/d2713bcbab254dd8beaf4a1d8cdde925
Autor:
Glenn A. Reinhart, Paul C. Harrison, Kathleen Lincoln, Hongxing Chen, Peng Sun, Jon Hill, Hu Sheng Qian, Mark C. McHugh, Holly Clifford, Khing Jow Ng, Hong Wang, Danielle Fowler, Kristina Gueneva-Boucheva, Jehrod B. Brenneman, Todd Bosanac, Diane Wong, Ryan M. Fryer, Chris Sarko, Carine M. Boustany-Kari, Steven S. Pullen
Publikováno v:
The Journal of pharmacology and experimental therapeutics.
Activation of soluble guanylate cyclase (sGC) to restore cyclic guanosine monophosphate (cGMP) and improve functionality of nitric oxide (NO) pathways impaired by oxidative stress is a potential treatment for diabetic and chronic kidney disease. We r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62247eda3ea47ef82756bd1ee47aafe3
https://pubmed.ncbi.nlm.nih.gov/36507845
https://pubmed.ncbi.nlm.nih.gov/36507845
Autor:
Amin Abedini, Ziyuan Ma, Julia Frederick, Poonam Dhillon, Michael S. Balzer, Rojesh Shrestha, Hongbo Liu, Steven Vitale, Kishor Devalaraja-Narashimha, Paola Grandi, Tanmoy Bhattacharyya, Erding Hu, Steven S. Pullen, Carine M Boustany-Kari, Paolo Guarnieri, Anil Karihaloo, Hanying Yan, Kyle Coleman, Matthew Palmer, Lea Sarov-Blat, Lori Morton, Christopher A. Hunter, Mingyao Li, Katalin Susztak
Kidneys have one of the most complex three-dimensional cellular organizations in the body, but the spatial molecular principles of kidney health and disease are poorly understood. Here we generate high-quality single cell (sc), single nuclear (sn), s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef1d19933dc237011cb55146afd17db
https://doi.org/10.1101/2022.10.24.513598
https://doi.org/10.1101/2022.10.24.513598
Autor:
Amin, Abedini, Yuan O, Zhu, Shatakshee, Chatterjee, Gabor, Halasz, Kishor, Devalaraja-Narashimha, Rojesh, Shrestha, Michael S, Balzer, Jihwan, Park, Tong, Zhou, Ziyuan, Ma, Katie Marie, Sullivan, Hailong, Hu, Xin, Sheng, Hongbo, Liu, Yi, Wei, Carine M, Boustany-Kari, Uptal, Patel, Salem, Almaani, Matthew, Palmer, Raymond, Townsend, Shira, Blady, Jonathan, Hogan, Lori, Morton, Katalin, Susztak, Yan, Zhong
Publikováno v:
J Am Soc Nephrol
Background Microscopic analysis of urine sediment is probably the most commonly used diagnostic procedure in nephrology. The urinary cells, however, have not yet undergone careful unbiased characterization. Methods Single-cell transcriptomic analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aecdd46cc7b24323f737c5968ff4cc1
https://doi.org/10.1681/asn.2020050757
https://doi.org/10.1681/asn.2020050757
Autor:
Junnan Wu, Matthew J. Seasock, Pazit Beckerman, Jeffrey B. Kopp, Andreas Linkermann, Joseph Wahba, Xin Sheng, Jay J. Kuo, Katalin Susztak, Archana Raman, Steven S. Pullen, Carine M. Boustany-Kari, Nathan J Coffey, Ziyuan Ma, Matthew Palmer, Dorottya Laczkó
Publikováno v:
J Clin Invest
Coding variants in apolipoprotein L1 (APOL1), termed G1 and G2, can explain most excess kidney disease risk in African Americans; however, the molecular pathways of APOL1-induced kidney dysfunction remain poorly understood. Here, we report that expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dd6eb1999cb9898ee39e78487de6a1
https://doi.org/10.1172/jci136329
https://doi.org/10.1172/jci136329
Autor:
Jon Hill, Kathleen E. Corey, Dagmar Knebel, Raymond T. Chung, Lorena Pantano, Eric Simon, Shannan J. Ho Sui, George Agyapong, Zhu Zhuo, Julia F Doerner, Carine M. Boustany-Kari, Francesc Fernandez-Albert, Yang Shen, Jörg F. Rippmann, Werner Rust
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. In adults with NAFLD, fibrosis can develop and progress to liver cirrhosis and liver failure. However, the underlying molecular mechanisms of fibrosis prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ec28ef9f5d0f2d3e96806fe5317345
https://doi.org/10.1038/s41598-021-96966-5
https://doi.org/10.1038/s41598-021-96966-5
Autor:
Behzad Najafian, Helen C. Looker, Robert G. Nelson, Cordell A. Esplin, Paolo Guarnieri, Jennifer L. Harder, Michael Mauer, Jon Hill, Carine M. Boustany-Kari, Matthias Kretzler, Pierre Jean Saulnier, Viji Nair
Publikováno v:
J Am Soc Nephrol
Background In type 1 diabetes, changes in the GFR and urine albumin-to-creatinine ratio (ACR) are related to changes in kidney structure that reflect disease progression. However, such changes have not been studied in type 2 diabetes. Methods Partici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fa5eeb94b5df3d129d08ca0c3bc26b
https://doi.org/10.1681/asn.2018111166
https://doi.org/10.1681/asn.2018111166