Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Carine Beaupere"'
Autor:
Carine Beaupere, Brian M. Wasko, Jared Lorusso, Brian K. Kennedy, Matt Kaeberlein, Vyacheslav M. Labunskyy
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 1884-1892 (2017)
Transcriptional regulation plays an important role in the control of gene expression during aging. However, translation efficiency likely plays an equally important role in determining protein abundance, but it has been relatively understudied in thi
Externí odkaz:
https://doaj.org/article/bffcdf2940bf49a0b7a1dcacbe9b2170
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 623 (2021)
Glucocorticoids (GCs) are steroids secreted by the adrenal cortex under the hypothalamic-pituitary-adrenal axis control, one of the major neuro-endocrine systems of the organism. These hormones are involved in tissue repair, immune stability, and met
Externí odkaz:
https://doaj.org/article/80de9fa1c19d4428b56f28bff88e27e7
Insulin resistance-driven beta-cell adaptation in mice: Mechanistic characterization and 3D analysis
Autor:
Alexandrine Liboz, Carine Beaupere, Natacha Roblot, Jean-Yves Tinevez, Sandra Guilmeau, Anne-Françoise Burnol, Dalale Gueddouri, Xavier Prieur, Bruno Fève, Ghislaine Guillemain, Bertrand Blondeau
Aims/hypothesisPancreatic beta cells secrete insulin to control glucose homeostasis. Beta cells can also adapt their function and mass when more insulin is required, especially in situations of insulin resistance (IR). Beta-cell mass adaptation can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0aeccc61c9f5cdb512ac83d882ac864
https://doi.org/10.1101/2023.01.09.523222
https://doi.org/10.1101/2023.01.09.523222
Autor:
Praveen K. Patnaik, Carine Beaupere, Hanna Barlit, Antonia María Romero, Mitsuhiro Tsuchiya, Michael Muir, María Teresa Martínez-Pastor, Sergi Puig, Matt Kaeberlein, Vyacheslav M. Labunskyy
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Iron dyshomeostasis contributes to aging, but little information is available about the molecular mechanisms. Here, we provide evidence that in Saccharomyces cerevisiae, aging is associated with altered expression of genes involved in iron homeostasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7838a31466ff6f2411c7c77b2e88062f
https://doi.org/10.1101/2022.02.25.480133
https://doi.org/10.1101/2022.02.25.480133
Autor:
Mitchell B. Lee, Matt Kaeberlein, Carine Beaupere, Lauren VanValkenburg, Michael G. Kiflezghi, Daniel E. L. Promislow, Weiwei Dang, Rosalyn B. Chen, Leticia Dinatto, Brian M. Wasko, Vyacheslav M. Labunskyy
Publikováno v:
Proceedings of the National Academy of Sciences. 115:9586-9591
The yeast genome becomes unstable during stress, which often results in adaptive aneuploidy, allowing rapid activation of protective mechanisms that restore cellular homeostasis. In this study, we performed a genetic screen in Saccharomyces cerevisia
During stress, accumulation of misfolded proteins in the endoplasmic reticulum (ER) triggers activation of the adaptive mechanisms that restore protein homeostasis. One mechanism that eukaryotic cells use to respond to ER stress is through activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab25268e4724ab6579bb5650f3ce9f60
https://europepmc.org/articles/PMC6421085/
https://europepmc.org/articles/PMC6421085/
Publikováno v:
Annales d'Endocrinologie. 81:188
Nous avons recemment demontre dans un modele murin d’insulinoresistance induit par la corticosterone la mise en place d’une adaptation des cellules beta pancreatiques caracterisee par la formation de nouvelles cellules beta (Courty et al, Diabete
Publikováno v:
Journal of Visualized Experiments.
Translation of mRNA into proteins is a complex process involving several layers of regulation. It is often assumed that changes in mRNA transcription reflect changes in protein synthesis, but many exceptions have been observed. Recently, a technique
Autor:
Jun Komatsu, Alba Cico, Raya Poncin, Maël Le Bohec, Jörg Morf, Stanislav Lipin, Antoine Graindorge, Hélène Eckert, Azadeh Saffarian, Léa Cathaly, Frédéric Guérin, Sara Majello, Damien Ulveling, Anaïs Vayaboury, Nicolas Fernandez, Dilyana Dimitrova, Xavier Bussell, Yannick Fourne, Pierre Chaumat, Barbara André, Elodie Baldivia, Ulysse Godet, Mathieu Guinin, Vivien Moretto, Joy Ismail, Olivier Caille, Natacha Roblot, Carine Beaupère, Alexandrine Liboz, Ghislaine Guillemain, Bertrand Blondeau, Pierre Walrafen, Stuart Edelstein
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Progress in sample preparation for scRNA-seq is reported based on RevGel-seq, a reversible-hydrogel technology optimized for samples of fresh cells. Complexes of one cell paired with one barcoded bead are stabilized by a chemical linker and
Externí odkaz:
https://doaj.org/article/a27fcb871ba44d87a05f139d18b0132e
Autor:
Brian M. Wasko, Jared S. Lorusso, Vyacheslav M. Labunskyy, Matt Kaeberlein, Brian K. Kennedy, Carine Beaupere
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 1884-1892 (2017)
Transcriptional regulation plays an important role in the control of gene expression during aging. However, translation efficiency likely plays an equally important role in determining protein abundance, but it has been relatively understudied in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656821658230658264af8b9af6509e51
https://europepmc.org/articles/PMC5327506/
https://europepmc.org/articles/PMC5327506/