Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carina Villacrés"'
Autor:
Benilde Mizero, Carina Villacrés, Victor Spicer, Rosa Viner, Julian Saba, Bhavinkumar Patel, Sergei Snovida, Penny Jensen, Andreas Huhmer, Oleg V. Krokhin
Publikováno v:
Journal of proteome research. 21(5)
We present the first detailed study of chromatographic behavior of peptides labeled with tandem mass tags (TMT and TMTpro) in 2D LC for proteomic applications. Carefully designed experimental procedures have permitted generating data sets of over 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd5e8b03af6ca96dfb8f627118aba66
https://pubmed.ncbi.nlm.nih.gov/35363494
https://pubmed.ncbi.nlm.nih.gov/35363494
Publikováno v:
Journal of biotechnology. 333
The control of glycosylation profiles is essential to the consistent manufacture of therapeutic monoclonal antibodies that may be produced from a variety of cell lines including CHO and NS0. Of particular concern is the potential for generating non-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c95185acc5fdd6ff2e1609bf609b781
https://pubmed.ncbi.nlm.nih.gov/33901620
https://pubmed.ncbi.nlm.nih.gov/33901620
Autor:
Leigh Owens, Vincent Jung, Kirsten Heimann, Narges Mashkour, Carina Villacrés, Michael Butler, Ali Razaghi
Publikováno v:
Experimental Cell Research. 359:20-29
Human interferon gamma (hIFNγ) affects tumour cells and modulates immune responses, showing promise as an anti-cancer biotherapeutic. This study investigated the effect of glycosylation and expression system of recombinant hIFNγ in ovarian carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09878eab155f8948ac9311129a85a30
https://doi.org/10.1016/j.yexcr.2017.08.014
https://doi.org/10.1016/j.yexcr.2017.08.014
Autor:
Ian C. Schoenhofen, Yves Durocher, Paul Lopez, Michael Butler, Edward Bodnar, Céline Raymond, Hélène Perreault, Carina Villacrés
Publikováno v:
Analytical and Bioanalytical Chemistry. 407:8945-8958
Metabolic engineering of glycans present on antibodies and other glycoproteins is becoming an interesting research area for improving our understanding of the glycome. With knowledge of the sialic acid biosynthetic pathways, the experiments described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd59e4c3c1890284c2d1ff456f64cf64
https://doi.org/10.1007/s00216-015-9010-x
https://doi.org/10.1007/s00216-015-9010-x
Publikováno v:
Biotechnology Journal. 10:1051-1066
Controlled feeding of glucose has been employed previously to enhance the productivity of recombinant glycoproteins but there is a concern that low concentrations of glucose could limit the synthesis of precursors of glycosylation. Here we investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4aa66117246c4b507bc04a00be055c
https://doi.org/10.1002/biot.201400662
https://doi.org/10.1002/biot.201400662
Autor:
Edward Bodnar, Céline Raymond, Paul G. Lopez, Carina Villacrés, Michael Butler, Ian C. Schoenhofen, Yves Durocher, Hélène Perreault
Publikováno v:
Analytical and Bioanalytical Chemistry. 407:9191-9193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::887a6087957e5122cc7cd53dbbf435dc
https://doi.org/10.1007/s00216-015-9158-4
https://doi.org/10.1007/s00216-015-9158-4
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1321
Nucleotide sugars are the donor substrates of glycosyltransferases and their availability is known to have an impact on the glycosylation of recombinant proteins including monoclonal antibodies. In addition, the intracellular concentration levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00773d5032974cec2242fed12faaf5de
https://pubmed.ncbi.nlm.nih.gov/26082234
https://pubmed.ncbi.nlm.nih.gov/26082234
Publikováno v:
Glyco-Engineering ISBN: 9781493927593
Nucleotide sugars are the donor substrates of glycosyltransferases and their availability is known to have an impact on the glycosylation of recombinant proteins including monoclonal antibodies. In addition, the intracellular concentration levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bb85d6eda37e0e68aa40d73b7903d89
https://doi.org/10.1007/978-1-4939-2760-9_24
https://doi.org/10.1007/978-1-4939-2760-9_24
