Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Carina Stenfors"'
Autor:
Sammeli Liikkanen, Mika Mäkinen, Teppo Huttunen, Toni Sarapohja, Carina Stenfors, Christopher Eccleston
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
IntroductionChronic low back pain (CLBP) is a major public health problem. Reliably measuring the effects of chronic pain on movement and activity, and any changes due to treatment, is a healthcare challenge. A recently published paper demonstrated t
Externí odkaz:
https://doaj.org/article/a6aa897cee8e4a0090375bbd7aa1f892
Autor:
Christopher Eccleston, Emma Fisher, Sammeli Liikkanen, Toni Sarapohja, Carina Stenfors, Satu K. Jääskeläinen, Andrew S.C. Rice, Leena Mattila, Taru Blom, J. Raymond Bratty
Publikováno v:
Eccleston, C, Fisher, E, Liikkanen, S, Sarapohja, T, Stenfors, C, Jääskeläinen, S K, Rice, A S C, Mattila, L, Blom, T & Bratty, J R 2022, ' A prospective, double-blind, pilot, randomized, controlled trial of an "embodied" virtual reality intervention for adults with low back pain ', Pain, vol. 163, no. 9, pp. 1700-1715 . https://doi.org/10.1097/j.pain.0000000000002617
Adults with chronic low back pain, disability, moderate-to-severe pain, and high fear of movement and reinjury were recruited into a trial of a novel, automated, digital therapeutics, virtual reality, psychological intervention for pain (DTxP). We co
Autor:
Andrew S.C. Rice, Camilla I. Svensson, Rosie Morland, Anton Pekcec, Natalie J. Gardiner, Marcin Ligocki, Sabrina Voß, Ada Delaney, Thomas Christoph, Luke A. Bryden, Carina Stenfors, Rolf-Detlef Treede, Ian Machin, Kris Rutten, Camilla Ultenius, Katsuhiro Uto, A. Robens, Ombretta Caspani, Nick Andrews, Annika Lindsten, Dominic L. Li, Kazumi Yamamoto, Suguru Koyama, Wenlong Huang, Märta Segerdahl, Jeffrey D. Kennedy, Rachel Wodarski, Catherine Baastrup, Sanziana M. Rotariu
Publikováno v:
Wodarski, R, Delaney, A, Ultenius, C, Morland, R, Andrews, N, Baastrup, C, Bryden, L, Caspani, O, Christoph, T, Gardiner, N, Huang, W, Kennedy, J D, Koyama, S, Li, D, Ligocki, M, Lindsten, A, Machin, I, Pekcec, A, Robens, A, Rotariu, S M, Voss, S, Segerdahl, M, Stenfors, C, Svensson, C I, Treede, R-D, Uto, K, Yamamoto, K, Rutten, K & Rice, A S C 2016, ' Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study ', Pain, vol. 157, no. 10, pp. 2350-2365 . https://doi.org/10.1097/j.pain.0000000000000657
Pain
Pain
Supplemental Digital Content is Available in the Text. This unique multicenter approach provides high-quality evidence validating burrowing as a robust and reproducible outcome measure to infer the global effect of pain on rodents.
Burrowing, an
Burrowing, an
Publikováno v:
European Journal of Pharmacology. 756:75-84
Lack of predictive power for drug effects has been a major criticism against animal pain models. It is therefore important to define the utility and limitations of different models. The aim of this study was to extend previous work on gait analysis a
Autor:
Jarmo Immonen, Carina Stenfors, Johanna Holappa, Kristina Ängeby Möller, Heta Svärd, Anni Suominen
Publikováno v:
Journal of neuroscience methods. 300
Background There is a need for better joint pain treatment, but development of new medication has not been successful. Pre-clinical models with readouts that better reflect the clinical situation are needed. In patients with joint pain, pain at rest
Monosodium iodoacetate-induced monoarthritis develops differently in knee versus ankle joint in rats
Autor:
Anja Finn, Camilla I. Svensson, Frank Seeliger, Kristina Ängeby Möller, Stephanie Klein, Carina Stenfors
Publikováno v:
Neurobiology of Pain
Highlights • Ankle versus knee joint injection of MIA in rats resulted in different behavioural profiles. • Levels of biochemical mediators differs between ankle and knee injection of MIA in rats. • Histopathological analysis show different res
Autor:
Rachel Wodarski, Andrew S.C. Rice, Margarita Calvo, Ombretta Caspani, K.L. Knopp, Rolf-Detlef Treede, Isabel A Lefevre, Ian Machin, H. Rees, Jordi Serra, Kris Rutten, Wenlong Huang, Malcolm R. Macleod, Nanna B. Finnerup, A.W. Bannon, Cathrine Baastrup, Jeffrey D. Kennedy, Gillian L. Currie, M. Segerdahl, Carina Stenfors, O.-G. Berge
Publikováno v:
Knopp, K L, Stenfors, C, Baastrup, C S, Bannon, A W, Calvo, M, Caspani, O, Currie, G, Finnerup, N B, Huang, W, Kennedy, J D, Lefevre, I, Machin, I, Mcleod, M, Rees, H, Rice, A S C, Rutten, K, Segerdahl, M, Serra, J, Wodarski, R, Berge, O-G & Treede, R-D 2015, ' Experimental design and reporting standards for improving the internal validity of pre-clinical studies in the field of pain: Consensus of the IMI-Europain consortium ', Scandinavian Journal of Pain, vol. 7, pp. 58-70 . https://doi.org/10.1016/j.sjpain.2015.01.006
Background and aimsPain is a subjective experience, and as such, pre-clinical models of human pain are highly simplified representations of clinical features. These models are nevertheless critical for the delivery of novel analgesics for human pain,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86988b97aa1416382de31bfc2432c0c9
https://pure.au.dk/portal/da/publications/experimental-design-and-reporting-standards-for-improving-the-internal-validity-of-preclinical-studies-in-the-field-of-pain-consensus-of-the-imieuropain-consortium(17b0998a-0a6f-4147-8ea2-903e85dec209).html
https://pure.au.dk/portal/da/publications/experimental-design-and-reporting-standards-for-improving-the-internal-validity-of-preclinical-studies-in-the-field-of-pain-consensus-of-the-imieuropain-consortium(17b0998a-0a6f-4147-8ea2-903e85dec209).html
Autor:
Carin Wallsten, Ingalill Gagner Milchert, Göran Öjteg, Carina Stenfors, Eva Jerning, Nina Mohell, Svante B. Ross, Seth-Olov Thorberg
Publikováno v:
CNS Drug Reviews. 5:213-232
Autor:
Anders Eriksson, Pernilla Tellefors, Åsa Malmberg, Charlotte Ahlgren, Carina Stenfors, Svante B. Ross
Publikováno v:
European Journal of Pharmacology. 499:67-75
The in vitro pharmacological properties of AR-A000002 (( R )- N -[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide), a novel 5-hydroxytryptamine (5-HT) 1B receptor antagonist, were studied. AR-A000002 bound wit
Publikováno v:
Molecular Brain Research. 126:74-77
Glutamate transporters regulate the glutamate concentration in the synaptic cleft within the CNS, a regulation required for normal brain function. In several neurological conditions, the amount of glutamate is altered. One reason for the changes in g