Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carina Schludi"'
Autor:
Masin Abo-Rady, Norman Kalmbach, Arun Pal, Carina Schludi, Antje Janosch, Tanja Richter, Petra Freitag, Marc Bickle, Anne-Karin Kahlert, Susanne Petri, Stefan Stefanov, Hannes Glass, Selma Staege, Walter Just, Rajat Bhatnagar, Dieter Edbauer, Andreas Hermann, Florian Wegner, Jared L. Sterneckert
Publikováno v:
Stem Cell Reports, Vol 14, Iss 3, Pp 390-405 (2020)
Summary: In amyotrophic lateral sclerosis (ALS) motor neurons (MNs) undergo dying-back, where the distal axon degenerates before the soma. The hexanucleotide repeat expansion (HRE) in C9ORF72 is the most common genetic cause of ALS, but the mechanism
Externí odkaz:
https://doaj.org/article/15576128a76a4db4a3714084cbbcfe19
Active poly‐GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model
Autor:
Qihui Zhou, Nikola Mareljic, Meike Michaelsen, Samira Parhizkar, Steffanie Heindl, Brigitte Nuscher, Daniel Farny, Mareike Czuppa, Carina Schludi, Alexander Graf, Stefan Krebs, Helmut Blum, Regina Feederle, Stefan Roth, Christian Haass, Thomas Arzberger, Arthur Liesz, Dieter Edbauer
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 2, Pp 1-13 (2019)
Abstract The C9orf72 repeat expansion is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and/or frontotemporal dementia (FTD). Non‐canonical translation of the expanded repeat results in abundant poly‐GA inclusion pathology t
Externí odkaz:
https://doaj.org/article/94311c357d894315a7a860a7ca6f1ed6
Autor:
Florian Wegner, Selma Staege, Andreas Hermann, Stefan Stefanov, Hannes Glass, Susanne Petri, Dieter Edbauer, Rajat Bhatnagar, Antje Janosch, Petra Freitag, Anne-Karin Kahlert, Marc Bickle, Jared Sterneckert, Tanja Richter, Arun Pal, Carina Schludi, Walter Just, Norman Kalmbach, Masin Abo-Rady
Publikováno v:
Stem Cell Reports, Vol 14, Iss 3, Pp 390-405 (2020)
Stem Cell Reports
Stem cell reports 14(3), 390-405 (2020). doi:10.1016/j.stemcr.2020.01.010
Stem Cell Reports
Stem cell reports 14(3), 390-405 (2020). doi:10.1016/j.stemcr.2020.01.010
Summary In amyotrophic lateral sclerosis (ALS) motor neurons (MNs) undergo dying-back, where the distal axon degenerates before the soma. The hexanucleotide repeat expansion (HRE) in C9ORF72 is the most common genetic cause of ALS, but the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e36d802ed14d96d26a9814e300c2698
http://www.sciencedirect.com/science/article/pii/S221367112030031X
http://www.sciencedirect.com/science/article/pii/S221367112030031X
Autor:
Mareike Czuppa, Ashutosh Dhingra, Qihui Zhou, Carina Schludi, Laura König, Elisabeth Scharf, Daniel Farny, Anupriya Dalmia, Joachim Täger, Melissa Castillo-Lizardo, Eszter Katona, Kohji Mori, Tina Aumer, Florian Schelter, Markus Müller, Thomas Carell, Tuomo Kalliokoski, Josef Messinger, Patrizia Rizzu, Peter Heutink, Dieter Edbauer
Publikováno v:
Cell reports 39(10), 110913 (2022). doi:10.1016/j.celrep.2022.110913
An intronic (G4C2)n expansion in C9orf72 causes amyotrophic lateral sclerosis and frontotemporal dementia primarily through gain-of-function mechanisms: the accumulation of sense and antisense repeat RNA foci and dipeptide repeat (DPR) proteins (poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d80e5107309f6513c9082a9eb5c9ec
https://doi.org/10.1016/j.celrep.2022.110913
https://doi.org/10.1016/j.celrep.2022.110913
Autor:
Mareike, Czuppa, Ashutosh, Dhingra, Qihui, Zhou, Carina, Schludi, Laura, König, Elisabeth, Scharf, Daniel, Farny, Anupriya, Dalmia, Joachim, Täger, Melissa, Castillo-Lizardo, Eszter, Katona, Kohji, Mori, Tina, Aumer, Florian, Schelter, Markus, Müller, Thomas, Carell, Tuomo, Kalliokoski, Josef, Messinger, Patrizia, Rizzu, Peter, Heutink, Dieter, Edbauer
Publikováno v:
Cell reports. 39(10)
An intronic (G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c067819e5874bd78738b84d563aab3f
https://pubmed.ncbi.nlm.nih.gov/35675776
https://pubmed.ncbi.nlm.nih.gov/35675776
Active poly‐GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model
Autor:
Regina Feederle, Dieter Edbauer, Christian Haass, Qihui Zhou, Stefan Roth, Carina Schludi, Helmut Blum, Meike Michaelsen, Mareike Czuppa, Alexander Graf, Stefan Krebs, Samira Parhizkar, Thomas Arzberger, Arthur Liesz, Brigitte Nuscher, Steffanie Heindl, Daniel Farny, Nikola Mareljic
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 2, Pp n/a-n/a (2020)
EMBO Mol. Med. 12:e10919 (2020)
EMBO molecular medicine 12(2), e10919 (2020). doi:10.15252/emmm.201910919
EMBO Molecular Medicine
EMBO Mol. Med. 12:e10919 (2020)
EMBO molecular medicine 12(2), e10919 (2020). doi:10.15252/emmm.201910919
EMBO Molecular Medicine
The C9orf72 repeat expansion is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and/or frontotemporal dementia (FTD). Non‐canonical translation of the expanded repeat results in abundant poly‐GA inclusion pathology throughout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75696b017d11a320e8ff35c1f6d55cc7
https://doaj.org/article/94311c357d894315a7a860a7ca6f1ed6
https://doaj.org/article/94311c357d894315a7a860a7ca6f1ed6