Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carina S Debes Marun"'
Autor:
Jitra Kriangkum, Sarah N Motz, Carina S Debes Marun, Sandrine T Lafarge, Spencer B Gibson, Christopher P Venner, James B Johnston, Andrew R Belch, Linda M Pilarski
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64927 (2013)
Clonal diversity in multiple myeloma (MM) includes both MM-related and MM-unrelated clonal expansions which are subject to dominance exerted by the MM clone. Here we show evidence for the existence of minor but highly expanded unrelated B-cell clones
Externí odkaz:
https://doaj.org/article/8f7197a1402f47988aaf48a320c703d0
The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma
Autor:
Morie A. Gertz, Martin M. Oken, Jerry M. Winkler, Gordon W. Dewald, Rafael Fonseca, Robert A. Kyle, Emily A. Blood, Natalia Gonzalez-Paz, Carina S. Debes-Marun, Philip R. Greipp, Martha Q. Lacy, Sandra C. Bryant, Angela Dispenzieri, Rafael Santana-Davila, Elisa B. Picken
Publikováno v:
Blood. 102:2562-2567
Aneuploid is ubiquitous in multiple myeloma (MM), and 4 cytogenetic subcategories are recognized: hypodiploid (associated with a shorter survival), pseudodiploid, hyperdiploid, and near-tetraploid MM. The hypodiploid, pseudodiploid, and near-tetraplo
Publikováno v:
Lab on a chip. 8(12)
Fluorescence in-situ hybridization (FISH) is more sensitive than classical cytogenetics for detecting cryptic chromosomal abnormalities. H; however, the protocol complexity, high reagent cost and long hybridization time associated with a typical inte
Publikováno v:
Blood. 116:4045-4045
Abstract 4045 Multiple Myeloma (MM) is characterized by accumulations of chromosomal abnormalities throughout the course of disease. Recurrent IgH translocations such as t(4;14) or deletion (del)13 occur during early stages of disease or perhaps as o
Publikováno v:
Blood. 106:500-500
Multiple Myeloma (MM) is clinically characterized by accumulations of plasma cells in the bone marrow (BM). We have identified drug resistant clonotypic B lymphocytes in the peripheral blood of MM patients that have malignant characteristics and the
Publikováno v:
Lab on a Chip; Dec2008, Vol. 8 Issue 12, p2151-2156, 6p