Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Carina Ng"'
Autor:
Nicholas A Graham, Aspram Minasyan, Anastasia Lomova, Ashley Cass, Nikolas G Balanis, Michael Friedman, Shawna Chan, Sophie Zhao, Adrian Delgado, James Go, Lillie Beck, Christian Hurtz, Carina Ng, Rong Qiao, Johanna ten Hoeve, Nicolaos Palaskas, Hong Wu, Markus Müschen, Asha S Multani, Elisa Port, Steven M Larson, Nikolaus Schultz, Daniel Braas, Heather R Christofk, Ingo K Mellinghoff, Thomas G Graeber
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 2, Pp n/a-n/a (2017)
Abstract Copy number alteration (CNA) profiling of human tumors has revealed recurrent patterns of DNA amplifications and deletions across diverse cancer types. These patterns are suggestive of conserved selection pressures during tumor evolution but
Externí odkaz:
https://doaj.org/article/ecca9cc2cad345a0a0b562644ca81d88
Autor:
Nikolaus Schultz, Michael C. Friedman, Carina Ng, Johanna ten Hoeve, Nicholas A. Graham, Hong Wu, Nikolas G. Balanis, Anastasia Lomova, Daniel Braas, Sophie Zhao, James Go, Ashley A. Cass, Rong Qiao, Christian Hurtz, Thomas G. Graeber, Adrian Delgado, Shawna Chan, Markus Müschen, Elisa Port, Nicolaos Palaskas, Aspram Minasyan, Steven M. Larson, Lillie Beck, Heather R. Christofk, Ingo K. Mellinghoff, Asha S. Multani
Publikováno v:
Molecular systems biology, vol 13, iss 2
Molecular Systems Biology
Molecular Systems Biology
Copy number alteration (CNA) profiling of human tumors has revealed recurrent patterns of DNA amplifications and deletions across diverse cancer types. These patterns are suggestive of conserved selection pressures during tumor evolution but cannot b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f716fc6b11a8964bca84976afd8ddc05
https://escholarship.org/uc/item/6vs2896r
https://escholarship.org/uc/item/6vs2896r
Autor:
Zhengshan Chen, Christian Hurtz, Chuanxin Huang, Mohammed Firas Sadiyah, Srividya Swaminathan, Richard C. Harvey, Carina Ng, Daniel Nowak, Markus Müschen, Kazuhiko Igarashi, Björn Titz, Andrew G. Hall, Gabriela B. Thoennissen, William L. Carroll, Thomas G. Graeber, Huimin Geng, Cheryl L. Willman, Vikki Rand, Huining Kang, Ari Melnick, H. Phillip Koeffler
Publikováno v:
Nature medicine, vol 19, iss 8
The B cell-specific transcription factor BACH2 is required for affinity maturation of B cells. Here we show that Bach2-mediated activation of p53 is required for stringent elimination of pre-B cells that failed to productively rearrange immunoglobuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b93ed5c8ac47ee8c48df3c84b13a7c5
https://doi.org/10.1038/nm.3247
https://doi.org/10.1038/nm.3247
Autor:
Kalika L. Bandamwar, Jessie Huang, David Cheung, Eric B. Papas, Ling Lee, Qian Garrett, Carina Ng
Publikováno v:
Contact Lens and Anterior Eye. 33:199-201
Purpose To evaluate the early phase time course of solution induced corneal staining. Methods and materials A double masked, single centred, prospective clinical trial was conducted. Twenty-five participants, either experienced or new contact lens we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7531ff1610f24b405679010ef76137a0
https://doi.org/10.1016/j.clae.2010.02.004
https://doi.org/10.1016/j.clae.2010.02.004
Autor:
Seyedmehdi Shojaee, Zhengshan Chen, Carina Ng, Andreas Hochhaus, Christian Hurtz, Grace Liu, Daniel Braas, Scott A. Armstrong, Huimin Geng, Lai N. Chan, Thomas G. Graeber, Keith R. Yamamoto, Ross A. Dickins, Steven M. Kornblau, H. Phillip Koeffler, Thomas Ernst, Valeria Cazzaniga, Thomas A. Milne, Giovanni Cazzaniga, Markus Müschen
Publikováno v:
Blood. 126:1255-1255
Oncogenic lesions in hematopoietic progenitor cells give rise to B-cell or myeloid malignancies. While often transformed by the same oncogenes, B-cell and myeloid leukemias markedly differ in biological and clinical characteristics. Our metabolic ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5acc075ca6b12d0065f82057a9db6739
https://doi.org/10.1182/blood.v126.23.1255.1255
https://doi.org/10.1182/blood.v126.23.1255.1255
Autor:
Thomas Ernst, Seyedmehdi Shojaee, Daniel Braas, Thomas G. Graeber, Andreas Hochhaus, Valeria Cazzaniga, Behzad Kharabi Masouleh, Steven M. Kornblau, Carina Ng, Giovanni Cazzaniga, Huimin Geng, Nianxiang Zhang, Yihua Qiu, Kevin R. Coombes, Lai N. Chan, Christian Hurtz
Publikováno v:
Cancer Research. 75:1124-1124
Oncogenic lesions in multi-potent progenitor cells often give rise to either B-cell or myeloid lineage leukemia. While transformed by the same oncogenes (e.g. BCR-ABL1, RAS), B-lineage and myeloid leukemias are distinct diseases. Given that oncogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba1d261e0c9e80f05671e23c8c486fe1
https://doi.org/10.1158/1538-7445.am2015-1124
https://doi.org/10.1158/1538-7445.am2015-1124
Autor:
Seyedmehdi Shojaee, Lai N. Chan, Christian Hurtz, Markus Müschen, Carina Ng, Huimin Geng, Behzad Kharabi
Publikováno v:
Cancer Research. 74:2447-2447
Background & Hypothesis: The serine-threonine liver kinase B1 (LKB1) activates AMP-activated protein kinase (AMPK) and negatively regulates aerobic glycoloysis (Warburg effect). LKB1 and AMPK have long been established as tumor suppressors, leading t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36420ac41e4b9a54374ca05ac7358766
https://doi.org/10.1158/1538-7445.am2014-2447
https://doi.org/10.1158/1538-7445.am2014-2447
Autor:
Christian Hurtz, Huimin Geng, Erica Ballabio, Gang Xiao, Carina Ng, Behzad Kharabi Masouleh, Cheryl L. Willman, Scott A. Armstrong, Thomas Milne, Ari Melnick, Markus Muschen
Publikováno v:
Blood. 122:72-72
Background BCL6 has been identified in diffuse large B cell lymphoma (DLBCL), where it is frequently translocated to immunoglobulin loci and acts as a protoncogene and transcriptional repressor. We found in Ph+ acute lymphoblastic leukemia (ALL) that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a229fbcbe41f997afa525b8293063fd3
https://doi.org/10.1182/blood.v122.21.72.72
https://doi.org/10.1182/blood.v122.21.72.72
Publikováno v:
Blood. 116:4199-4199
Abstract 4199 Background: The pre-B cell receptor promotes differentiation of normal pre-B cells and couples the immunoglobulin μ-chain to activating tyrosine kinases (e.g. SYK) via linker molecules (e.g. BLNK). We recently established that the pre-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f5c47b7d2d6a910a98a32a151644e56
https://doi.org/10.1182/blood.v116.21.4199.4199
https://doi.org/10.1182/blood.v116.21.4199.4199