Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Carina Mauersberger"'
Autor:
Ulrike Meyer-Lindemann, Carina Mauersberger, Anna-Christina Schmidt, Aldo Moggio, Julia Hinterdobler, Xinghai Li, David Khangholi, Jan Hettwer, Christian Gräßer, Alexander Dutsch, Heribert Schunkert, Thorsten Kessler, Hendrik B. Sager
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundInflammation strongly contributes to atherosclerosis initiation and progression. Consequently, recent clinical trials pharmacologically targeted vascular inflammation to decrease the incidence of atherosclerosis-related complications. Colch
Externí odkaz:
https://doaj.org/article/28df352c26204badaafd3cad9c9270cf
Autor:
Carina Mauersberger, Julia Hinterdobler, Heribert Schunkert, Thorsten Kessler, Hendrik B. Sager
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Atherosclerosis is the leading cause of death worldwide and leukocyte recruitment is a key element of this phenomenon, thus allowing immune cells to enter the arterial wall. There, in concert with accumulating lipids, the invading leukocytes trigger
Externí odkaz:
https://doaj.org/article/410e36e781ef42f3a18332b7c98ffd63
Publikováno v:
Cells, Vol 10, Iss 2, p 440 (2021)
Although the importance of inflammation in atherosclerosis is now well established, the exact molecular processes linking inflammation to the development and course of the disease are not sufficiently understood. In this context, modern genetics—as
Externí odkaz:
https://doaj.org/article/199cd9e34c9f47dc82c26b9ee8332b3f
Autor:
Nicholas H Adamstein, Wolfgang Koenig, Peter Libby, Christian Weber, Paul M. Ridker, Marcus-André Deutsch, Oliver Soehnlein, Carina Mauersberger, Hendrik B. Sager, Quinte Braster, Avril A. B. Robertson, Jan Hettwer, Benedikt Miritsch, Mark E. Cooper, Heribert Schunkert, Markus Krane, Xinghai Li, Aldo Moggio, Julia Hinterdobler, Hermann Gram, Olaf Groß, Thorsten Kessler
Publikováno v:
Cardiovascular Research, 118(13):337, 2778-2791. Oxford University Press
AIMS: Targeting vascular inflammation represents a novel therapeutic approach to reduce complications of atherosclerosis. Neutralizing the pro-inflammatory cytokine interleukin-1β (IL-1β) using canakinumab, a monoclonal antibody, reduces the incide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b40381ee58a84da0a5dd30ae3c8b8d7
https://doi.org/10.1093/cvr/cvab337
https://doi.org/10.1093/cvr/cvab337
Autor:
Peter Sandner, Lisa Dietz, Jana Wobst, Thorsten Kessler, Tan An Dang, Simon Koplev, Heribert Schunkert, Jens Schlossmann, Oliver Soehnlein, Frank Wunder, Hendrik B. Sager, N. Bettaga, J.L.M. Bjoerkegren, Carina Mauersberger, M. Stroth, Andreas Friebe, L. Lambrecht
AimThe role of platelets in atherosclerosis remains incompletely understood. Variants in genes encoding the soluble guanylyl cyclase (sGC) in platelets are associated with coronary artery disease (CAD) risk. Here we sought to investigate the contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c0793a52202643c561964e4a3538f9e
https://doi.org/10.1101/2021.11.15.467680
https://doi.org/10.1101/2021.11.15.467680
Autor:
Hendrik B. Sager, Carina Mauersberger
Publikováno v:
CardioVasc. 19:28-33
Inflammatorische Prozesse spielen eine wesentliche Rolle in der Entstehung und Progression kardiovaskularer Erkrankungen. Nachdem in praklinischen Studien gezeigt wurde, dass Inflammation auch ein therapeutisches Target darstellen kann, wurde in der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d5c8a36e78f7aafa3721043df95fd2
https://doi.org/10.1007/s15027-019-1539-8
https://doi.org/10.1007/s15027-019-1539-8
Publikováno v:
Cells, Vol 10, Iss 440, p 440 (2021)
Cells
Cells
Although the importance of inflammation in atherosclerosis is now well established, the exact molecular processes linking inflammation to the development and course of the disease are not sufficiently understood. In this context, modern genetics—as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01cbde24b1239119eb9018a72d2dae3
https://pubmed.ncbi.nlm.nih.gov/33669721
https://pubmed.ncbi.nlm.nih.gov/33669721
Autor:
Alexandra Baecklund, Hong Jin, Philipp Müller, Oliver Soehnlein, Peter Libby, Christian Weber, W.E. Kempf, Michael Hristov, Chien-Sin Chen, Philip Wenzel, Michael Molitor, Markus Krane, Matthias Nahrendorf, Lars Maegdefessel, Anna-Sophia Zimmermann, Karl-Heinz Ladwig, Christoph Scheiermann, Anna-Lena Steinsiek, Julia Hinterdobler, Jana Wobst, Almut Meesmann, Thorsten Kessler, Hendrik B. Sager, Quinte Braster, Aldo Moggio, Maarten Hulsmans, Ingo Hilgendorf, Baiba Vilne, Carina Mauersberger, Simin Schott, Heribert Schunkert
Publikováno v:
European Heart Journal, 42(39), 4077-+. Oxford University Press
European Heart Journal
European heart journal, Vol. 42, No 39 (2021) pp. 4077-4088
Eur. Heart J. 42, 4077–4088 (2021)
European Heart Journal
European heart journal, Vol. 42, No 39 (2021) pp. 4077-4088
Eur. Heart J. 42, 4077–4088 (2021)
Aims Mental stress substantially contributes to the initiation and progression of human disease, including cardiovascular conditions. We aim to investigate the underlying mechanisms of these contributions since they remain largely unclear. Methods an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5791577d2759f300f425588a3e5d0546
https://mediatum.ub.tum.de/doc/1639710/document.pdf
https://mediatum.ub.tum.de/doc/1639710/document.pdf
Autor:
Mauersberger C; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany.; These authors contributed equally: Carina Mauersberger, Hendrik B. Sager., Sager HB; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany.; These authors contributed equally: Carina Mauersberger, Hendrik B. Sager., Wobst J; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany., Dang TA; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany., Lambrecht L; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany., Koplev S; Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, UK., Stroth M; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany., Bettaga N; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany., Schlossmann J; Department of Pharmacology and Toxicology, University of Regensburg, Regensburg, Germany., Wunder F; Bayer AG, R&D Pharmaceuticals, Wuppertal, Germany., Friebe A; Institute of Physiology, Julius Maximilian University of Würzburg, Würzburg, Germany., Björkegren JLM; Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Neo, Karolinska Institutet, Karolinska Universitetssjukhuset, Huddinge, Sweden.; Department of Cardiac Surgery and The Heart Clinic, Tartu University Hospital and Department of Cardiology, Institute of Clinical Medicine, Tartu University, Tartu, Estonia., Dietz L; Bayer AG, R&D Pharmaceuticals, Wuppertal, Germany., Maas SL; Institute for Molecular Cardiovascular Research and Interdisciplinary Centre for Clinical Research, Rhine-Westphalia Technical University of Aachen, Aachen, Germany., van der Vorst EPC; Institute for Molecular Cardiovascular Research and Interdisciplinary Centre for Clinical Research, Rhine-Westphalia Technical University of Aachen, Aachen, Germany.; Institute for Cardiovascular Prevention, Ludwig Maximilian University of Munich, Munich, Germany., Sandner P; Bayer AG, R&D Pharmaceuticals, Wuppertal, Germany., Soehnlein O; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany.; Institute for Cardiovascular Prevention, Ludwig Maximilian University of Munich, Munich, Germany.; Institute for Experimental Pathology, University of Münster, Münster, Germany.; Department of Physiology and Pharmacology and Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Schunkert H; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany.; These authors jointly supervised this work: Heribert Schunkert, Thorsten Kessler., Kessler T; German Heart Centre Munich, Department of Cardiology, Technical University of Munich, Munich, Germany.; German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany.; These authors jointly supervised this work: Heribert Schunkert, Thorsten Kessler.
Publikováno v:
Nature cardiovascular research [Nat Cardiovasc Res] 2022 Dec; Vol. 1 (12), pp. 1174-1186. Date of Electronic Publication: 2022 Dec 12.