Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Carina Mallard"'
Autor:
Tetyana Chumak, Amandine Jullienne, C. Joakim Ek, Maryam Ardalan, Pernilla Svedin, Ryan Quan, Arjang Salehi, Sirus Salari, Andre Obenaus, Zinaida S Vexler, Carina Mallard
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Infection during the perinatal period can adversely affect brain development, predispose infants to ischemic stroke and have lifelong consequences. We previously demonstrated that diet enriched in n-3 polyunsaturated fatty acids (n-3 PUFA) t
Externí odkaz:
https://doaj.org/article/171dee11aa984a618f77b1c77a287ac0
Autor:
Seyedeh Marziyeh Jabbari Shiadeh, Fanny Goretta, Pernilla Svedin, Thomas Jansson, Carina Mallard, Maryam Ardalan
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Children born to obese mothers are at increased risk of developing mood disorders and cognitive impairment. Experimental studies have reported structural changes in the brain such as the gliovascular unit as well as activation of
Externí odkaz:
https://doaj.org/article/b3b29d7042994deb929c981b96d56841
Autor:
Gisela Nilsson, Amin Mottahedin, Aura Zelco, Volker M. Lauschke, C. Joakim Ek, Juan Song, Maryam Ardalan, Sha Hua, Xiaoli Zhang, Carina Mallard, Henrik Hagberg, Jianmei W. Leavenworth, Xiaoyang Wang
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 8, Pp 336-353 (2023)
Abstract Abnormal myelination underlies the pathology of white matter diseases such as preterm white matter injury and multiple sclerosis. Osteopontin (OPN) has been suggested to play a role in myelination. Murine OPN mRNA is translated into a secret
Externí odkaz:
https://doaj.org/article/3051a4998a3a476e9b6f2a2f9b0668b3
Therapeutic Effect of Nicotinamide Mononucleotide for Hypoxic–Ischemic Brain Injury in Neonatal Mice
Autor:
Takuya Kawamura, Gagandeep Singh Mallah, Maryam Ardalan, Tetyana Chumak, Pernilla Svedin, Lina Jonsson, Seyedeh Marziyeh Jabbari Shiadeh, Fanny Goretta, Tomoaki Ikeda, Henrik Hagberg, Mats Sandberg, Carina Mallard
Publikováno v:
ASN Neuro, Vol 15 (2023)
A clinical challenge remains in the treatment of hypoxic–ischemic brain injury in newborns. Nicotinamide adenine dinucleotide (NAD + ) has beneficial effects in animal models of adult stroke. Here, we aimed to understand the short- and long-term ne
Externí odkaz:
https://doaj.org/article/b0ce2f7a267f4400b808330c8df39e82
Autor:
Giacomo Gravina, Maryam Ardalan, Tetyana Chumak, Anders K. Nilsson, Joakim C. Ek, Hanna Danielsson, Pernilla Svedin, Milos Pekny, Marcela Pekna, Karin Sävman, Ann Hellström, Carina Mallard
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107217- (2023)
Summary: Staphylococcus (S.) epidermidis is the most common nosocomial coagulase-negative staphylococci infection in preterm infants. Clinical signs of infection are often unspecific and novel markers to complement diagnosis are needed. We investigat
Externí odkaz:
https://doaj.org/article/a44cb6ecd6a142a8a294c75645383909
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Ischemic stroke induces the activation and recruitment of peripheral leukocytes to the injured brain. These cells can infiltrate the brain through multiple routes, either by penetrating blood–brain barrier or via blood–CSF bar
Externí odkaz:
https://doaj.org/article/3fcf7e253167454c9a44212fd978b08f
Autor:
Gisela Nilsson, Ana A. Baburamani, Mary A. Rutherford, Changlian Zhu, Carina Mallard, Henrik Hagberg, Regina Vontell, Xiaoyang Wang
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Osteopontin (OPN) is a matricellular protein that mediates various physiological functions and is implicated in neuroinflammation, myelination, and perinatal brain injury. However, its expression in association with brain injury in preterm i
Externí odkaz:
https://doaj.org/article/b3d39e980e9345bf96d936bd08505dfd
Publikováno v:
Heliyon, Vol 8, Iss 7, Pp e09871- (2022)
The dynamic geometry of neuronal development is an essential concept in theoretical neuroscience. We aimed to design a mathematical model which outlines stepwise in an innovative form and designed to model neuronal development geometrically and model
Externí odkaz:
https://doaj.org/article/810a87cf2ec449f694273968ffd6df83
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Background Neonatal encephalopathy often leads to lifelong disabilities with limited treatments currently available. The brain vasculature is an important factor in many neonatal neurological disorders but there is a lack of diagnostic tools
Externí odkaz:
https://doaj.org/article/4f4f566860f3458190cc2a014017f653
Autor:
Andrea Pozo-Rodrigálvarez, YiXian Li, Anna Stokowska, Jingyun Wu, Verena Dehm, Hana Sourkova, Harry Steinbusch, Carina Mallard, Henrik Hagberg, Milos Pekny, Marcela Pekna
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Hypoxic-ischemic neonatal encephalopathy due to perinatal asphyxia is the leading cause of brain injury in newborns. Clinical data suggest that brain inflammation induced by perinatal insults can persist for years. We previously showed that signaling
Externí odkaz:
https://doaj.org/article/7eaffa3174164f069d43137e2db8505b